I-Ticagrelor Newgreen Supply APIs 99% Ticagrelor Powder
Incazelo Yomkhiqizo
I-Ticagrelor iyisidakamizwa se-antiplatelet, i-P2Y12 receptor antagonist, esetshenziselwa ngokuyinhloko ukuvimbela izenzakalo zenhliziyo, ikakhulukazi ezigulini ezine-acute coronary syndrome (ACS). Yehlisa ubungozi be-thrombosis ngokuvimbela ukuhlangana kweplatelet.
Oomakhenikha abakhulu
Vimbela ukuhlangana kweplatelet:
I-Ticagrelor ibophezela ngokuhlehla ku-receptor ye-P2Y12 endaweni yeplatelet, ivimbela ukusebenza kweplatelet kanye nokuhlanganiswa okubangelwa i-adenosine diphosphate (ADP), ngaleyo ndlela inciphisa ukubunjwa kwe-thrombus.
Izinkomba
I-Ticagrelor isetshenziswa ikakhulukazi ezimweni ezilandelayo:
I-Acute Coronary Syndrome:Kubandakanya iziguli ezine-angina engazinzile kanye ne-myocardial infarction, ngokuvamile esetshenziswa ngokuhambisana ne-aspirin ukuze kuncishiswe ingozi yezenzakalo zenhliziyo nemithambo yegazi.
Ukuvimbela okwesibili kwezenzakalo zenhliziyo nemithambo yegazi:Ezigulini esezivele zinesigameko senhliziyo ukuvimbela esinye.
I-COA
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | Impushana emhlophe | Iyahambisana |
| Oda | Isici | Iyahambisana |
| Isivivinyo | ≥99.0% | 99.8% |
| Kunambithile | Isici | Iyahambisana |
| Ukulahlekelwa Ekumisweni | 4-7(%) | 4.12% |
| Umlotha Ophelele | 8% Ubukhulu | 4.85% |
| Insimbi Enzima | ≤10(ppm) | Iyahambisana |
| I-Arsenic(As) | 0.5ppm Max | Iyahambisana |
| Ukuhola(Pb) | 1 ppm Max | Iyahambisana |
| I-Mercury(Hg) | 0.1ppm Max | Iyahambisana |
| Inani Lepuleti Eliphelele | 10000cfu/g Ubukhulu. | 100cfu/g |
| Imvubelo & Isikhunta | 100cfu/g Ubukhulu. | ＞20cfu/g |
| I-Salmonella | Okubi | Iyahambisana |
| E.Coli. | Okubi | Iyahambisana |
| I-Staphylococcus | Okubi | Iyahambisana |
| Isiphetho | Ufanelekile | |
| Isitoreji | Gcina endaweni evalwe kahle enezinga lokushisa eliphansi njalo futhi akukho ukukhanya kwelanga okuqondile. | |
| Impilo yeshelufu | Iminyaka emi-2 lapho igcinwe kahle | |
I-Side Effect
I-Ticagrelor ngokuvamile ibekezelelwa kahle, kodwa eminye imiphumela emibi ingase yenzeke, kuhlanganise:
Ukopha:Umthelela oseceleni ovame kakhulu, ongaholela ezenzakalweni zokopha okuncane noma okubi kakhulu.
Ukuphefumula kanzima:Ezinye iziguli zingase zibe nobunzima bokuphefumula noma ukukhwehlela.
Ukusabela kwamathumbu:njengokucanuzela kwenhliziyo, ubuhlungu besisu noma ukungagayeki kahle kokudla.
Amanothi
Ingozi yokopha:Ingozi yokopha kufanele ihlolwe njalo uma usebenzisa i-Ticagrelor, ikakhulukazi uma isetshenziswe ngokuhambisana nezinye izidakamizwa ze-anticoagulant.
Umsebenzi Wesibindi:Sebenzisa ngokuqapha ezigulini ezinokukhubazeka kwe-hepatic; ukulungiswa komthamo kungase kudingeke.
Ukusebenzisana kwezidakamizwa:I-Ticagrelor ingase ihlanganyele nezinye izidakamizwa. Kufanele utshele udokotela wakho ngazo zonke izidakamizwa ozithathayo ngaphambi kokuzisebenzisa.
Iphakheji Nokulethwa
