Bacopa monnieri, eyaziwa nangokuthi yiBrahmi eSanskrit naseBrain Tonic ngesiNgisi, ingumhlambi we-ayurvedic ovame ukusetshenziswa. Ukubukeza okusha kwesayensi kusho ukuthi i-Indian Ayurvedic herb bacopa monnieri ikhonjiswe ukusiza ukuvikela isifo sase-Alzheimer's. Ukubuyekezwa, okushicilelwe ejeni le-Science Drug Disturge Inthights, kwaqhutshwa yiqembu labaphenyi baseMalawi abavela eTaylor University e-United States bahlole imiphumela yezempilo yama-bacosides, ingxenye ye-bioactive yesitshalo.
Ukuqopha izifundo ezimbili ezenziwa ngonyaka ka-2011, abacwaningi bathi ama-bacosides angavikela ubuchopho ngomonakalo oxegative ukulimala okuhlobene nobudala ngezinqubo eziningi. Njenge-glycoside ye-non-polar, ama-bacosides angawela isithiyo segazi-ubuchopho nge-lipid-medied elungiselelwe ngokungenakuqhathaniswa. Ngokusekelwe ezifundweni ezedlule, abacwaningi bathi ama-bacosides nawo angathuthukisa umsebenzi wokuqonda ngenxa yezakhiwo zayo zamahhala ze-scavelling.
Ezinye izinzuzo zezempilo zeama-bacosidesFaka ama-neurons avikela ubuthi be-auness anβ, i-peptide edlala indima ebalulekile kwi-pathogenesis yesikhangiso ngoba ingahlangana kwi-amyloid fibrils. Lokhu kubuyekezwa kuveza ukusetshenziswa okusebenzayo kweBacopa Monnieri ezisetshenzisweni eziqondayo nezinezinzwane, futhi izitshalo zalo zemvelo zingasetshenziselwa ukuthuthukiswa kwezidakamizwa ezintsha ezinemininingwane ehlukahlukene nemvelo, ikakhulukazi iBacopa Monnieri, ikakhulukazi ekwakhiweni kwemikhiqizo yendabuko kanye nasekuthuthukisweni kwemikhiqizo yendabuko.
● Izinzuzo eziyisithupha zeBacopa monnieri
1.Ehlisa inkumbulo nokuqonda
I-BacoPa inezinzuzo eziningi zokudlidliza, kepha kungenzeka yaziwa kakhulu ngekhono layo lokuthuthukisa inkumbulo nokuqonda. Indlela yokuqala laphoIbhacAIthuthukisa inkumbulo nokuqonda ukuxhumana okuthuthukisiwe kwe-synaptic. Ngokukhethekile, i-herb ikhuthaza ukukhula nokwanda kwama-dendrites, athuthukisa ukusayina kwe-nerve.
Qaphela: Ama-Dendrites angezelwa kwe-nerve ye-nerve enjengezimpawu ezingenayo, ngakhoqinisa lokhu "izintambo" zokuxhumana kohlelo lwezinzwa ngokugcina kuthuthukisa umsebenzi wokuqonda.
Ucwaningo luthole ukuthi i-BACOSITE-a avusa amangqamuzana ezinzwa, okwenza ama-synapses amukeleke kakhulu ekutholeni izinzwa ezingenayo. I-BacoPa nayo ikhonjiswe ukuthuthukisa inkumbulo nokuqonda ngokuvuselela umsebenzi we-hippocampal ngokwandisa umsebenzi we-protein kinase emzimbeni, oguqula izindlela ezahlukahlukene zeselula.
Njengoba iHippocampus ibalulekile cishe kuyo yonke imisebenzi yokuqonda, abacwaningi bakholelwa ukuthi kungenye yezindlela eziyisisekelo iBacopa ethuthukisa ubuchopho.
Ezinye izifundo zikhombisile ukuthi ukusekelwa kwansuku zonkeBacopa monnieri(Ku-DOSES ka-300-640 mg ngosuku) kungathuthukisa:
Ukusebenzela inkumbulo
Imemori Yendawo
Inkumbulo engazi lutho
Ukuqaphela
Izinga lokufunda
Ukuhlanganiswa kwememori
Umsebenzi wokukhumbula
Khumbula amagama
Inkumbulo ebonakalayo
2.Redering nengcindezi nokukhathazeka
Noma ngabe yizezimali, ezenhlalo, ngokomzimba, ngokwengqondo, noma ezingokomzwelo, inkinga ephezulu kakhulu empilweni yabantu abaningi. Manje kunanini ngaphambili, abantu babheke ukubaleka nganoma yiziphi izindlela ezidingekayo, kufaka phakathi izidakamizwa notshwala. Kodwa-ke, izinto ezinjengezidakamizwa notshwala zingaba nemiphumela emibi empilweni yomuntu wengqondo nangokomzimba.
Ungahle ube nentshisekelo yokwazi lokhoIbhacAInomlando omude wokusebenzisa njengohlelo lwezinzwa lwezinzwa ukuze unciphise imizwa yokukhathazeka, ukukhathazeka, kanye nengcindezi.Lokhu ngenxa ye-bacopa's Properties, ethuthukisa amandla omzimba wethu wokubhekana, ubhekane nombuyisene ekucindezelekeni (ngengqondo, ngokomzimba nangokomzimba). I-Bacopa inezinhlaka eziguqukayo ngokwengxenye ngenxa yokulawulwa kwayo kwama-neurotransmitters, kepha lo mumbi wakudala unamazinga e-cortisol.
Njengoba kungenzeka wazi, iCortisol yi-hormone eyinhloko yomzimba. Ukuxineka okungamahlalakhona namazinga aphakeme ama-cortisol angalimaza ubuchopho bakho.Iqiniso, ama-neuroscientists athole ukuthi ukucindezelwa okungamahlalakhona kungadala izinguquko zesikhathi eside ngesakhiwo sobuchopho kanye nomsebenzi, okuholela ekucindezelweni kwamaprotheni athile okulimaza ama-neurons.
Ukucindezelwa okungamahlalakhona kuholela ekulimaleni oxIdative kuma-neurons, okungaba nemiphumela ehlukahlukene emibi, kufaka phakathi:
Ukulahleka Kwememori
Ukufa kweseli ye-Neuron
Ukwenza izinqumo okulimazayo
I-ATROPY yobuchopho bengqondo.
I-Bacopa Monnieri inezakhiwo ezinamandla zokunciphisa izingcindezi, ezi-neuroptoptive. Izifundo zabantu zibhale imiphumela ye-adadoogenic yeBacopa Monnieri, kubandakanya ukunciphisa i-cortisol. I-cortisol ephansi iholela ekunciphiseni imizwa yokuxineka, engakwazi ukuthuthukisa umoya kuphela, kepha futhi kwandise ukugxila nokukhiqiza. Ngaphezu kwalokho, ngoba iBacopa Monnieri ilawula i-dopamine ne-serotonin, ingabeka izinguquko ezibangelwa ukucindezelwa e-Dopamine nase-serotonin eHippocampus kanye ne-cortex yangaphambili, egcizelela futhi izimfanelo ze-admonogenic zale mbamba.
Bacopa monnieriFuthi kwandisa ukukhiqizwa kwe-tryptophan hydroxylase (TPH2), i-enzyme ebalulekile emisebenzini ehlukahlukene ye-Central Nerpy System, kufaka phakathi i-serotonin synthesis. Okubaluleke kakhulu, i-BACOSITE-A, esinye sezithako eziphambili ezisebenzayo eBacopa Monnieri, kukhonjisiwe ukukhulisa umsebenzi we-GABA. IGaba iyisisulu sokuthoba, inhibitory neurotransmitter. I-Bacopa Monieri ingabeka umsebenzi we-GABA futhi yehlise umsebenzi we-glutamate, okungasiza ukunciphisa imizwa yokukhathazeka ngokunciphisa ukwenziwa kwe-neurons okungahle kwenziwe ngengcindezi.
Isikhathi Sokuthumela: Oct-08-2024
