Yini?I-Coenzyme Q10?
I-Coenzyme Q10 (i-Coenzyme Q10, i-CoQ10), eyaziwa nangokuthi i-Ubiquinone (UQ) ne-Coenzyme Q (CoQ), iyi-coenzyme ekhona kuzo zonke izinto eziphilayo ze-eukaryotic ezenza ukuphefumula kwe-aerobic. Kuyinhlanganisela ye-benzoquinone encibilika ngamafutha enesakhiwo esifana ne-vitamin K. Q imele iqembu le-quinone, futhi u-10 umele inombolo ye-isoprene enamathiselwe emsileni wayo. Ikakhulukazi yakheka kulwelwesi lwangaphakathi lwe-mitochondria, kanti ingxenye encane ingabuye itholakale ngokudla, njengenkomo, amaqanda, izinhlanzi ezinamafutha, amantongomane, amawolintshi, i-broccoli nezinye izithelo nemifino.
I-Coenzyme Q10 isatshalaliswa kabanzi emzimbeni womuntu futhi ikhona ezithweni ezihlukahlukene, izicubu, izingxenye ezingaphansi kwe-subcellular kanye ne-plasma, kodwa okuqukethwe kwayo kuyahluka kakhulu. I-mass concentration iphezulu ezicutshini nasezithweni ezifana nesibindi, inhliziyo, izinso namanyikwe. Umsebenzi oyinhloko ukushayela amangqamuzana omuntu ukuze akhiqize amandla. I-Coenzyme Q10 ibandakanyeka kakhulu ku-mitochondrial oxidative phosphorylation kanye nenqubo yokukhiqiza ye-ATP, ilawula indawo ye-cell redox, ithwala ama-electron ancishisiwe iwayise ku-vesicle noma iwakhiphe engqamuzaneni ngesikhathi senqubo yokungena kwe-electron membrane, futhi ibamba iqhaza ekwakhiweni kwe-proton gradient ulwelwesi lwangaphakathi kanye nolwelwesi lwe-plasma. Ingasheshisa ukuvuselelwa kwamangqamuzana futhi ikhuthaze ukusebenza kwamangqamuzana, ngaleyo ndlela ikhuthaze kakhulu amandla amangqamuzana okumunca imisoco. Ukwengeza izithako ze-coenzyme Q10 emikhiqizweni yokunakekelwa kwesikhumba kungasiza ngempumelelo amangqamuzana esikhumba ukuthi amunce ezinye izakhamzimba emikhiqizweni yokunakekelwa kwesikhumba, futhi kunemiphumela egcina impilo njengokusheshisa ukugaya kanye nokunciphisa ukuguga.
Njengomkhiqizo wezempilo, i-coenzyme Q10 inemisebenzi yokuvikela inhliziyo, ukukhulisa amandla, nokwenza ngcono ukungatheleleki. Ilungele abasubathi, abasebenzi bengqondo abaphezulu, kanye nokuzinza nokubuyiselwa kweziguli ezinesifo senhliziyo, isifo sikashukela, njll.
Izakhiwo zePhysical And Chemical ofI-Coenzyme Q10
Ukubukeka kwe-Coenzyme Q10:I-crystalline powder ephuzi noma e-orange-yellow; ayinaphunga futhi ayinambitheki; ukubola kalula ngokukhanya.
Umbala:okusawolintshi okukhanyayo kuya kuwolintshi omnyama
Iphoyinti lokuncibilika:49-51℃
Indawo yokubilisa:715.32 ℃
Ukuminyana:0.9145 g/cm3
Inkomba ye-refractive:1.4760
Izimo zesitoreji:Ingagcinwa ekamelweni lokushisa isikhathi esifushane, okungcono ku-−20 ℃ ukuze igcinwe isikhathi eside.
Ukunyibilika:Incibilika kalula ku-chloroform.
Ukuzwela:ukuzwela kwesithombe
Ukuzinza:Izinzile, kodwa iyazwela ekukhanyeni noma ekushiseni, ayihambelani nama-oxidants aqinile.
Ukusabalalisa KweI-Coenzyme Q10Emzimbeni Womuntu
I-Coenzyme Q10 ikhona kakhulu kulwelwesi lwamaseli, ikakhulukazi kulwelwesi lwe-mitochondrial, futhi isatshalaliswa kakhulu enhliziyweni, amaphaphu, isibindi, izinso, ubende, amanyikwe nezindlala ze-adrenal. Ingqikithi yomzimba we-Coenzyme Q10 ingu-500 ~ 1500mg kuphela, kodwa idlala indima ebalulekile. I-Coenzyme Q10 iphakeme kakhulu enhliziyweni, izinso, isibindi nemisipha. Ngesikhathi esifanayo, i-95% ye-Coenzyme Q10 emzimbeni womuntu ikhona ngesimo se-ubiquinol (i-Ubiquinol encishisiwe), kodwa ubuchopho namaphaphu afakiwe. Kucatshangwa ukuthi kungase kube ngenxa yokucindezeleka okuphezulu kwe-oxidative kulezi zicubu ezimbili, okwenza i-ubiquinol ibe yi-ubiquinone ene-oxidized (i-Ubiquinone ene-oxidized).
Ngokuncipha kweminyaka yobudala, okuqukethwe kwe-Coenzyme Q10 emzimbeni womuntu kuzokwehla kancane kancane. Ukuthatha iminyaka engu-20 njengomugqa ojwayelekile, lapho uneminyaka engama-80, ukuncishiswa kwemvelo kweCoenzyme Q10 ezingxenyeni ezihlukahlukene zomzimba womuntu: isibindi: 83.0%; izinso: 65,3%; iphaphu: 51,7%; inhliziyo: 42.9%. Ngakho-ke, ngokuvamile kuyamukelwa ukuthi inhliziyo iyisitho esidinga kakhulu i-coenzyme Q10 supplementation, noma ukuthi izinkinga eziningi zenhliziyo asebekhulile zivela ngenxa yokuntuleka kwe-coenzyme Q10.
Yiziphi Izinzuzo ZazoI-Coenzyme Q10?
Ezinye zezinzuzo ezingaba khona ze-CoQ10 zifaka:
1. Impilo yenhliziyo ethuthukisiwe:I-CoQ10 iboniswe ukuthi isekela impilo yenhliziyo ngokusiza ukuthuthukisa ukukhiqizwa kwamandla emisipha yenhliziyo, kanye nokusebenza njenge-antioxidant yokuvikela ekucindezelekeni kwe-oxidative.
2. Ukwanda kokukhiqizwa kwamandla:I-CoQ10 ibandakanyeka ekukhiqizweni kwe-adenosine triphosphate (ATP), okuwumthombo wamandla oyinhloko wamaseli. Ukwengeza nge-CoQ10 kungasiza ekwandiseni amazinga wamandla, ikakhulukazi kubantu abanamazinga aphansi e-CoQ10.
3. Izakhiwo ze-Antioxidant:I-CoQ10 isiza ukunciphisa ama-radicals mahhala futhi inciphise ukulimala kwe-oxidative emzimbeni, engasiza ukuvikela ezifweni ezihlukahlukene ezingapheli futhi isekele impilo yonke.
4. Imiphumela engase ibe khona yokulwa nokuguga:Olunye ucwaningo luphakamisa ukuthi i-CoQ10 ingase ibe nemiphumela yokulwa nokuguga ngenxa yekhono layo lokuvikela amangqamuzana emonakalweni we-oxidative futhi isekele ukukhiqizwa kwamandla kwamaselula.
5. Ukwesekwa kwabasebenzisi be-statin:Imithi ye-Statin, evame ukunikezwa ukwehlisa i-cholesterol, ingaqeda amazinga e-CoQ10 emzimbeni. Ukwengeza nge-CoQ10 kungasiza ekwehliseni imiphumela emibi yokusetshenziswa kwe-statin, njengobuhlungu bemisipha nobuthakathaka.
Ziyini Izicelo ZeI-Coenzyme Q10?
I-Coenzyme Q10 (CoQ10) inezinhlelo zokusebenza ezimbalwa ngenxa yezinzuzo zayo zezempilo ezingaba khona. Ezinye zezinhlelo zokusebenza ezibalulekile ze-CoQ10 zifaka:
1. Impilo yenhliziyo:I-CoQ10 ivame ukusetshenziselwa ukusekela impilo yenhliziyo, ikakhulukazi kubantu abanesifo senhliziyo, umfutho wegazi ophakeme, noma ezinye izimo zenhliziyo. Kungasiza ukuthuthukisa ukukhiqizwa kwamandla emisipha yenhliziyo futhi kusebenze njenge-antioxidant yokuvikela ekucindezelekeni kwe-oxidative.
2. Ukuphazamiseka kweMitochondrial:I-CoQ10 ngezinye izikhathi isetshenziswa njengesengezo kubantu abanokuphazamiseka kwe-mitochondrial, njengoba idlala indima ebalulekile ekukhiqizweni kwamandla ngaphakathi kwe-mitochondria.
3. I-myopathy eyenziwe nge-statin:I-CoQ10 supplementation ngezinye izikhathi iyanconywa kubantu abaphuza imithi ye-statin ukuze behlise i-cholesterol, njengoba ama-statins ehlisa amazinga e-CoQ10 emzimbeni. Ukwengeza nge-CoQ10 kungasiza ekudambiseni ubuhlungu bemisipha nobuthakathaka obuhlobene nokusetshenziswa kwe-statin.
4. Anti-ukuguga nempilo yesikhumba:I-CoQ10 isetshenziswa kweminye imikhiqizo ye-skincare ngenxa yezakhiwo zayo ze-antioxidant, ezingasiza ukuvikela isikhumba emonakalweni we-oxidative futhi isekele impilo yesikhumba iyonke.
5. Ukuvimbela I-Migraine:Olunye ucwaningo lubonisa ukuthi ukwesekwa kwe-CoQ10 kungasiza ekunciphiseni imvamisa nobukhulu be-migraines, nakuba izifundo ezengeziwe zidingeka ukuze kuqinisekiswe ukusebenza kwayo kule njongo.
6. Ukuzivocavoca umzimba:I-CoQ10 ingasiza ukuthuthukisa ukusebenza kokuzivocavoca kanye nokululama ngokusekela ukukhiqizwa kwamandla nokunciphisa ukucindezeleka okwenziwe nge-oxidative emisipha.
Okuqukethwe kwe-Coenzyme q10 Ekudleni Okujwayelekile
| Okuqukethwe kwe-Coenzyme Q10 ngekhilogremu ngayinye yokudla (mg) | |||
| Ukudla | Okuqukethwe kwe-CoQ10 | Ukudla | Okuqukethwe kwe-CoQ10 |
| Amasardine | 33.6 | Ukolweni | 6.9 |
| I-Saury | 26.8 | Irayisi elinsundu | 5.4 |
| Inhliziyo yengulube | 25.6 | Isipinashi | 5.1 |
| Isibindi sengulube | 25.1 | Imifino eluhlaza | 3.2 |
| Izinhlanzi ezimnyama | 25.1 | Imbewu yokudlwengulwa | 2.7 |
| Inyama yengulube | 24.7 | Izaqathi | 2.6 |
| Uhlobo lwenhlanzi | 22.5 | Ulethisi | 2.5 |
| I-Mackerel | 21.8 | Utamatisi | 2.5 |
| Yenkomo | 21.2 | I-Kiwifruit | 2.4 |
| Inyama yengulube | 16.1 | Isilimo esidliwayo esinamagatsha anamanzi | 2.3 |
| Amantongomane | 11.3 | Ubhatata | 2.3 |
| I-broccoli | 10.8 | Amawolintshi | 2.3 |
| Ama-Cherries | 10.7 | Isitshalo seqanda | 2.3 |
| Ibhali | 10.6 | Uphizi | 2.0 |
| Ubhontshisi wesoya | 7.3 | Umsuka we-lotus | 1.3 |
Imibuzo Ehlobene Ongaba Nentshisekelo Kuyo:
Iyini imiphumela emibiI-Coenzyme Q10?
I-Coenzyme Q10 (CoQ10) ngokuvamile ibhekwa njengephephile kubantu abaningi uma ithathwa ngemithamo efanele. Nokho, abanye abantu bangase babe nemiphumela engemihle. Lokhu kungafaka:
1. Izinkinga zokugaya ukudla:Abanye abantu bangase babe nezimpawu ezithambile zesisu ezifana nokucanuzela kwenhliziyo, isifo sohudo, noma ukucasuka kwesisu lapho bethatha izithasiselo ze-CoQ10.
2. Ukuqwasha:Kwezinye izimo, ukwesekwa kwe-CoQ10 kuye kwahlotshaniswa nobunzima bokulala noma ukuqwasha, ikakhulukazi uma kuthathwa kusihlwa.
3. Ukungezwani komzimba:Nakuba kungavamile, abanye abantu bangase bangezwani ne-CoQ10 futhi bangase babe nezimpawu ezinjengokuqubuka, ukulunywa, noma ukuphefumula kanzima.
4. Ukusebenzisana nemithi:I-CoQ10 ingasebenzisana nemithi ethile, efana nemithi enciphisa igazi nemithi yomfutho wegazi ophakeme. Kubalulekile ukubonisana nochwepheshe bezempilo ngaphambi kokuthatha i-CoQ10 uma usebenzisa noma yimiphi imithi.
Kubalulekile ukuqaphela ukuthi iningi labantu liyibekezelela kahle i-CoQ10, futhi imiphumela emibi ayivamile. Kodwa-ke, njenganoma yisiphi isithasiselo, kuyatuseka ukuthintana nomhlinzeki wezempilo ngaphambi kokuqala i-CoQ10 supplementation, ikakhulukazi uma unezimo zempilo ezicashile noma uphuza imithi.
Ingabe kufanele uthathe i-CoQ10 nsuku zonke?
Isinqumo sokuthatha i-Coenzyme Q10 (CoQ10) nsuku zonke kufanele sisekelwe ezidingweni zezempilo zomuntu ngamunye kanye nezeluleko zochwepheshe bezempilo. I-CoQ10 ikhiqizwa ngokwemvelo emzimbeni futhi itholakala ngokudla okuthile. Nokho, njengoba abantu bekhula noma ezimeni ezithile zempilo, ukukhiqizwa kwemvelo komzimba kwe-CoQ10 kungase kwehle.
Kubantu abacabangela ukwesekwa kwe-CoQ10, kubalulekile ukuthintana nomhlinzeki wokunakekelwa kwezempilo ukuze unqume umthamo ofanele kanye nemvamisa ngokusekelwe esimweni sezempilo somuntu ngamunye, ukushiyeka okungenzeka, kanye nanoma yiziphi izimo zezokwelapha ezikhona. Kwezinye izimo, uchwepheshe wezokunakekelwa kwempilo angase atuse ukuthatha i-CoQ10 nsuku zonke, kuyilapho kwezinye izimo, ishejuli ehlukile yokudosa ingase ifaneleke kakhulu.
Ubani ongakwazi ukuthatha i-CoQ10?
Abantu abathile kufanele baqaphele noma bagweme ukuthatha i-Coenzyme Q10 (CoQ10) ngaphandle kokuthintana nochwepheshe bezempilo. Lokhu kungase kuhlanganise:
1. Abesifazane abakhulelwe noma abancelisa ibele:Nakuba i-CoQ10 ngokuvamile ibhekwa njengephephile, kunocwaningo olulinganiselwe mayelana nokuphepha kwayo phakathi nokukhulelwa nokuncelisa. Ngakho-ke, kuyatuseka ukuthi abesifazane abakhulelwe noma abancelisayo babonane nomhlinzeki wezempilo ngaphambi kokusebenzisa i-CoQ10.
2. Abantu abaphuza imithi yokunciphisa igazi:I-CoQ10 ingase ihlanganyele nemithi ye-anticoagulant efana ne-warfarin (Coumadin) noma izidakamizwa ze-antiplatelet njenge-aspirin. Kubalulekile ukuthi abantu abakule mithi bafune iseluleko sezokwelapha ngaphambi kokuqala i-CoQ10 supplementation.
3. Abantu abanezimo zezempilo ezikhona:Abantu abanezimo ezithile zezokwelapha, njengesifo sesibindi, isifo sezinso, noma isifo sikashukela, kufanele bathintane nomhlinzeki wezempilo ngaphambi kokuthatha i-CoQ10, njengoba ingase ihlanganyele nemithi esetshenziselwa ukuphatha lezi zimo.
4. Labo abanokungezwani komzimba owaziwayo:Abantu abaziyo ngokungezwani ne-CoQ10 noma izinhlanganisela ezihlobene kufanele bagweme ukusetshenziswa kwayo.
Yiziphi izimpawu zokudingaI-CoQ10?
Izimpawu zokudinga isithasiselo se-Coenzyme Q10 (CoQ10) aziqondile ngaso sonke isikhathi, njengoba zingase zicashe futhi zingase zidlulelane nezimpawu zezimo zezempilo ezahlukahlukene. Kodwa-ke, ezinye zezimpawu ezingase zibonise ukuntuleka kwe-CoQ10 zifaka:
1. Ukukhathala namazinga aphansi wamandla:I-CoQ10 idlala indima ebalulekile ekukhiqizeni amandla eselula. Ngakho-ke, ukukhathala okuqhubekayo kanye namazinga aphansi wamandla kungase kube uphawu lokuntuleka kwe-CoQ10.
2. Ubuthakathaka bemisipha nobuhlungu:Ukuntuleka kwe-CoQ10 kungase kube nomthelela ebuthakathakeni bemisipha, ubuhlungu, namajaqamba, njengoba kuhileleke ekukhiqizeni amandla ngaphakathi kwamaseli emisipha.
3. Umfutho wegazi ophezulu:Olunye ucwaningo lubonisa ukuthi amazinga aphansi e-CoQ10 angase ahlotshaniswe nomfutho wegazi ophakeme, futhi ukwesekwa kungasiza ukusekela impilo yenhliziyo nemithambo yegazi.
4. Isifo sezinsini:I-CoQ10 ihilelekile ekugcineni izicubu zezinsini ezinempilo, futhi ukuntula kungase kubangele isifo sezinsini noma izinkinga ze-periodontal.
5. Ikhanda elibuhlungu:Olunye ucwaningo luye lwabonisa ukuthi ukwesekwa kwe-CoQ10 kungasiza ekunciphiseni imvamisa nobukhulu be-migraines, okuphakamisa ukuthi amazinga aphansi e-CoQ10 angaba yimbangela ye-migraines kwabanye abantu.
Kuthatha isikhathi esingakanani ukubona izinzuzo?
Isikhathi esisithathayo ukuze ubone izinzuzo ze-Coenzyme Q10 (CoQ10) singahluka kuye ngesimo sezempilo somuntu ngamunye, isimo sezempilo esithile okukhulunywa ngaso, kanye nomthamo we-CoQ10 osetshenziswayo. Kwezinye izimo, abantu bangase bathole izinzuzo ngokushesha, kuyilapho kwezinye izimo, kungase kuthathe isikhathi eside ukuqaphela noma yimiphi imiphumela.
Ezimweni ezithile ezifana nokuhluleka kwenhliziyo noma umfutho wegazi ophakeme, kungase kuthathe amasonto ambalwa kuya ezinyangeni ze-CoQ10 engaguquki ukuze kubonwe ukuthuthuka kwezimpawu. Ngakolunye uhlangothi, abantu abathatha i-CoQ10 ukuze bathole ukwesekwa kwamandla okuvamile noma njenge-antioxidant bangase baqaphele izinzuzo ezinjengokwenyuka kwamazinga wamandla noma ukuphila kahle okuphelele phakathi nesikhathi esifushane, okungenzeka phakathi kwamaviki ambalwa.
Isikhathi sokuthumela: Sep-19-2024
