● Kungani umzimba womuntu uveza u-melanin?
Ukuvezwa kwelanga kuyimbangela enkulu yokukhiqizwa kwe-melanin. Imisebe ye-Ultraviolet ekulimaleni kwelanga i-Deoxyribonucleic acid, noma i-DNA, kumaseli. I-DNA eyonakalisiwe ingaholela ekulimaleni nasekuhlukeni kwemininingwane yofuzo, futhi idale ngisho nokuguqulwa kofuzo okulimazayo, noma ukulahlekelwa yizakhi zofuzo ze-supresressor, okuholela ekutheni kube nokuvela kwamathumba.
Kodwa-ke, ukuvezwa kwelanga akuyona "kubi", futhi konke "kunesikweletu" ku-melanin. Eqinisweni, ngezikhathi ezibucayi, uMelanin uzodedelwa ngempumelelo amandla emisebe ye-ultraviolet, ukuvimbela i-DNA ukuthi ilimele, ngaleyo ndlela yehlise umonakalo odalwe imisebe ye-ultraviolet emzimbeni womuntu. Yize uMelanin evikela umzimba womuntu kusuka kumonakalo we-ultraviolet, futhi angenza isikhumba sethu sibe mnyama futhi sithuthukise amabala. Ngakho-ke, ukuvimba ukukhiqizwa kwe-melanin kuyindlela ebalulekile yokumhlophe kwesikhumba embonini yobuhle.
● YiniI-Arbutin?
I-Arbutin, eyaziwa nangokuthi i-Arbutin, inefomula yamakhemikhali ye-C12h16o7. Kuyisithako esikhishwe emaqabungeni e-Ericaceae Plant Bearberry. Ingavimbela umsebenzi we-tyrosinase emzimbeni futhi ivikele ukukhiqizwa kuka-melanin, ngaleyo ndlela kunciphise imibala yesikhumba, ukususa amabala kanye nama-freckles. Ibuye ibe nemiphumela ye-bactericidal ne-anti-inflammatory futhi isetshenziswa ikakhulukazi kwezimonyo.
I-Arbutiningahlukaniswa ngohlobo lwe-α-β-hlobo ngokuya ngezakhiwo ezahlukahlukene. Umehluko omkhulu phakathi kwalezi ezimbili ezintweni ezibonakalayo ukujikeleza kwe-optical Bobabili banomphumela wokuvimbela iTyrosinase ukufeza mhlophe. Okusetshenziswa kakhulu yi-β-hlobo, eshibhile. Kodwa-ke, ngokocwaningo, engeza uhlobo lwe-α-olulingana no-1/9 lokuhlushwa kohlobo lwe-β-hlobo lungavimba ukukhiqizwa kwe-tyrosinase futhi kufinyeleleke mhlophe. Imikhiqizo eminingi yokunakekelwa kwesikhumba ene-α-Arbutin eyengeziwe inomphumela omhlophe ophakeme kayishumi kuphakeme kune-Arbutin yendabuko.
● Yiziphi izinzuzo zeI-Arbutin?
I-Arbutin ikhishwe ikakhulukazi emaqabungeni ebhere. Ingatholakala futhi kwezinye izithelo nezinye izitshalo. Inomphumela wokukhanyisa isikhumba. Ingangena ngokushesha esikhunjeni ngaphandle kokuthinta amaseli esikhumba. Kuhlanganisa ne-tyrosine, okubangela ukukhiqizwa kuka-melanin, futhi kungavimba ngempumelelo umsebenzi we-tyrosinase kanye nokukhiqizwa kuka-melanin, ukusheshisa ukubola nokuqedwa kwe-melanin. Ngaphezu kwalokho, i-Arbutin ingavikela isikhumba kusuka kuma-radicals samahhala futhi ine-hydrophility enhle. Ngakho-ke, kuvame ukungezwa emikhiqizweni yamhlophe emakethe, ikakhulukazi emazweni ase-Asia.
I-ArbutinIngabe into esebenzayo yemvelo ethathwe ezitshalweni eziluhlaza. Kuyingxenye ehlehlisayo yesikhumba ehlanganisa "izitshalo eziluhlaza, eziphephile futhi ezithembekile" kanye "nokuhlobisa okusebenzayo". Ingangena ngokushesha esikhunjeni. Ngaphandle kokuthinta okuhlushwa amaseli okuhlushwa, kungavimbela ngempumelelo umsebenzi we-tyrosinase esikhunjeni futhi uvimbe ukwakhiwa kwe-melanin. Ngokuhlanganisa ngokuqondile ne-tyrosinase, kusheshisa ukubola kanye nokukhipha i-melanin, kunciphisa imibala yesikhumba, ukususa amabala kanye nama-freckles, futhi akunangqondo neminye imiphumela emibi kuma-melanocytes. Iphinde ibe nemiphumela ye-bactericidal ne-anti-inflammatory. Kuyinto ephephe kakhulu futhi esebenza kahle kakhulu emhlophe ethandwayo ethandwa nanamuhla, futhi futhi iyisikhumba esimhlophe esimhlophe kanye ne-ejenti esebenzayo ngekhulu lama-21.
● Ukusetshenziswa okuyinhloko kweI-Arbutin?
Ingasetshenziswa ezimophini eziphezulu kakhulu futhi ingenziwa ngo-cream wesikhumba, ukhilimu we-freckle, ukhilimu we-pearl ophakeme, njll. Akukwazi ukwenza ubuhle be-pearl kuphela, kodwa futhi kube nokulwa nokuvuvukala kanye nokucasulwa.
Izinto ezivuthayo zomuthi ezishisiwe novalo: I-Arbutin isithako esiyinhloko somuthi omusha ovuthayo noweshweleka, obonakala ngokukhululeka okusheshayo kobuhlungu, okuqedwa okusheshayo kokuvuvukala nokuvuvukala okusheshayo, nokuphulukiswa okusheshayo, futhi akukho zibazi.
Ifomu lomthamo: fafaza noma ufake isicelo.
Izinto ezivuthiwe zemithi yokulwa nokuvuvukala kokuvuvukala: Imiphumela emihle yama-bactericidal kanye nokulwa nokuvuvukala, akukho miphumela emibi enobuthi.
● I-NewGreen Supply Alpha / Beta-I-ArbutinImpushana
Isikhathi sePosi: Dec-05-2024
