Kusukela kumshini wokusebenza oqinisekisiwe, i-NMN ikhethekileethuthelwa kumaseli nge-slc12a8 transporter kumaseli amathumbu amancane, futhi inyusa izinga le-NAD+ ezithweni ezahlukahlukene nezicubu zomzimba kanye nokujikeleza kwegazi.
Nokho, i-NMN yonakaliswa kalula ngemva kokuba umswakama nezinga lokushisa lifinyelele ukuphakama okuthile. Njengamanje, iningi le-NMN emakethe amaphilisi namaphilisi. Ngemuva kokuthatha amaphilisi noma amaphilisi e-NMN,iningi labo licekeleka phansi esiswini, futhi ingxenye encane kuphela ye-NMN efinyelela emathunjini amancane.
● Yiniliposomal NMN?
Ama-Liposomes "amasaka" ayindilinga enziwe ngama-molecule e-dicyclic fatty acid abizwa ngokuthi ama-phosphatidylcholine molecules (ama-phospholipid axhunywe ezinhlayiyeni ze-choline). "Amasaka" ayindilinga e-Liposome angasetshenziswa ukuhlanganisa izithasiselo zokudla okunomsoco njenge-NMN futhi zilethwe ngokuqondile kumaseli nezicubu zomzimba.
I-molecule ye-phospholipid iqukethe ikhanda le-hydrophilic phosphate kanye nemisila emibili ye-hydrophobic fatty acid. Lokhu kwenza i-liposome ibe umthwali wama-hydrophobic kanye nama-hydrophilic compounds. Ama-liposomes ama-lipid vesicles enziwe ngama-phospholipids ahlanganiswe ndawonye ukuze akhe ulwelwesi olukabili, njengawo wonke ulwelwesi lwamaseli emizimbeni yethu.
● Kwenzeka kanjaniliposome NMNukusebenza emzimbeni?
Esigabeni sokuqala sokusebenzisana kwe-liposome-cell,i-liposome NMN inamathela endaweni yeseli. Kulokhu kubopha, i-liposome NMN ifakwa ngaphakathi kuseli ngokusebenzisa indlela ye-endocytosis (noma i-phagocytosis).Ukulandela ukugaya kwe-enzymatic egunjini lamaselula,I-NMN ikhishelwa esitokisini, ukubuyisela umsebenzi wokuqala wokudla okunomsoco.
Inhloso yokuthatha noma yisiphi isithasiselo ukuqinisekisa ukuthi singena egazini ngolwelwesi lwamafinyila namaseli e-epithelial emathunjini. Kodwa-ke, ngenxa yezinga eliphansi lokumuncwa kanye nokuba khona kwe-bioavailability yamafomu endabuko e-NMN,isithako esisebenzayo silahlekelwa amandla ayo amaningi njengoba sidlula emgudwini wamathumbu, noma singamuncwa amathumbu amancane nhlobo.
Uma i-NMN ihlanganiswa ne-liposome, isiza kakhulu ekuthuthweni kwe-NMN futhi i-bioavailability ithuthukiswa kakhulu.
Ukulethwa okuhlosiwe
Ngokungafani nazo zonke ezinye izindlela zokulethwa kwe-NMN morphological,liposomal NMNinomsebenzi wokukhipha obambezelekile, okwandisa isikhathi sokujikeleza kwezakhi ezibalulekile egazini futhi kuthuthukisa kakhulu i-bioavailability.
Ukuphakama kwe-bioavailability yento esebenzayo, umphumela wayo omkhulu emzimbeni.
Ukumuncwa okuthuthukile
Liposome NMNimuncwa ngezinqubo ze-lymphatic kulwelwesi lwe-mucosal lomlomo namathumbu,i-metabolism ye-first pass kanye nokubola esibindini,ukuqinisekisa ukulondolozwa kobuqotho be-liposome NMN. I-synthesis yenziwa ukwenza i-NMN ibe lula ukuyihambisa ezithweni ezihlukahlukene.
Lokhu kumuncwa okuphezulu kusho ukusebenza kahle okuphezulu kanye nemithamo emincane ukuze uthole imiphumela engcono.
I-Biocompatibility
Atholakala kulwelwesi lwamaseli kuwo wonke umzimba, ama-phospholipids akhona ngokwemvelo, futhi umzimba uyawabona njengokuhambisana nomzimba futhi awuwaboni “njengobuthi” noma “owangaphandle” - ngakho-ke,ayiqalisi ukuhlasela kwamasosha omzimba ngokumelene ne-liposomal NMN.
Ukufihla ubuso
I-Liposomesvikela i-NMN ekubonweni amasosha omzimba,ukulingisa ama-biofilms kanye nokunikeza isithako esisebenzayo isikhathi esengeziwe sokufinyelela lapho siphokophele khona.
Ama-phospholipids afihla izithako ezisebenzayo ukuze amanani engeziwe akwazi ukumuncwa futhi abaleke umsebenzi okhethiwe wamathumbu amancane.
Yeqa umgoqo wegazi nobuchopho
I-Liposomes ikhonjisiweweqa umgoqo wegazi nobuchopho, okwenza ama-liposomes afake i-NMN ngokuqondile kumaseli futhi athuthukise ukujikeleza kwezakhi ngohlelo lwe-lymphatic.
● NEWGREEN Supply NMN Powder/Capsules/Liposomal NMN
Isikhathi sokuthumela: Oct-22-2024
