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Ukuchazwa Komkhiqizo
Ukwethulwa kwamaconsi e-folic acid
Amaconsi e-Folic acid anesengezo sokudla okunempilo nge-folic acid (Vitamin B9) njengesithako esiyinhloko. I-Folic acid iyi-vithan ethandwe ngamanzi kabanzi etholakala kabanzi emifino enamahlamvu aluhlaza, ubhontshisi, amantongomane kanye nezithelo ezithile. Idlala umsebenzi obalulekile womzimba emzimbeni, ikakhulukazi kwinqubo yokwahlukaniswa kweseli kanye nokuhlanganiswa kwe-DNA.
Izithako eziphambili
I-Folic acid: isakhi esiyinhloko, esibandakanyeka ekukhuleni kwamaseli nokuhlukaniswa, kubaluleke kakhulu empilweni yabesifazane abakhulelwe kanye nezingane.
Izinkomba
Abesifazane nabesifazane abakhulelwe bezama ukukhulelwa
Iziguli ezine-anemia
Abantu abadinga ukwandisa ukudla kwe-folic acid (njengama-imifino)
Umsebenzi
Amaconsi e-Folic acid avame ukuthathwa ngomlomo. Ukusetshenziswa okuqondile kanye nomthamo kufanele kulandele imiyalo yomkhiqizo noma izeluleko zikadokotela.
Amanothi
Abesifazane abakhulelwe kufanele balandele izeluleko zikadokotela babo lapho besebenzisa izithasiselo ze-folic acid ukuqinisekisa inani elifanele.
Abantu abangezwani ne-folic acid noma izithako zawo kufanele bagweme ukusetshenziswa.
Uma uzwa noma yikuphi ukungakhululeki ngesikhathi sokusebenzisa, yeka ukuthatha umuthi futhi ufune ukwelashwa ngokushesha.
Beka kafushane
Amaconsi e-Folic acid ayisengezo esibalulekile sokudla okunempilo, elungele ikakhulukazi abesifazane abakhulelwe nabantu abadinga ukwandisa ukudla kwe-folic acid. Lapho usebenzisa, kunconywa ukulandela ukuholwa kochwepheshe ukuqinisekisa ukuphepha nokusebenza ngempumelelo.
Coha
| Ukuzama | Amazinga | Umphumela | |
| Izici | I-ophuzi noma i-crystalline powder. Cishe i-infoluble emanzini nakuma-solvents amaningi we-organic. Iyancibilika kuma-dilifunces nasezixazululweni ze-alkaline | I-crystalline ephuzi. Cishe i-infoluble emanzini nakuma-solvents amaningi we-organic. Iyancibilika kuma-dilifunces nasezixazululweni ze-alkaline | |
|
Ukuhlonza (folic acid) | A: Ukujikeleza Okuthile Okubonakalayo | + 18 kuya ku- +22 (anhydrous into) | 19.2 |
| B: HPLC Ama-Chromatograms | Qhubelelayo | Qhubelelayo | |
| C: tlc Ukukhonjwa | Qhubelelayo | Qhubelelayo | |
|
Into ehlobene | Ukungcola okuvunyelwe ngaphezulu kwe-0.5% | 0.4 | |
| Ukungcola d hhayi ngaphezulu kwe-0.6% | 0.5 | ||
| Noma yikuphi okunye ukungcola okungabi ngaphezu kwe-0 5% | 0.4 | ||
| Isizonke okunye ukungcola okungabi ngaphezu kwe-1 0% | 0.8 | ||
| Isilinganiso sokutholwa kwe-UV | A256 / A365: 2.803.0 | I-2.90 | |
| Mahhala | Nmt 1/6 | 1/7 | |
| Ukungcola okuguquguqukayo | Kuvumelana | Kuvumelana | |
| Ubumsulwa be-chromatographic | Hhayi ngaphezulu kuka-25.0% | I-1.74% | |
| Umlotha ogcwele ama-sulphited | Hhayi ngaphezulu kuka-0.2% | 0. 13% | |
| Hola | 2ppm max | Kuvumelana | |
| Impilo yeshelufu | Iminyaka emi-2 lapho igcinwa kahle | ||
| Isiphetho: Kuhambisana ne-BP2002 / USP28 | Isiphetho: Kuhambisana ne-BP2002 / USP28 | ||
Sebenza
Imisebenzi yamaconsi e-folic acid ikakhulukazi ifaka phakathi izici ezilandelayo:
1. Khuthaza ukuhlukaniswa kweseli nokukhula:I-Folic acid iyilungu lamavithamini b. Kubandakanyeka ekuhlanganiseni kwe-DNA ne-RNA futhi kubalulekile ekuhlukaniseni okujwayelekile kanye nokukhula kwamaseli, ikakhulukazi kumaseli akhula ngokushesha (njengamaseli we-FETAL).
2. Ukuvimbela iziphambeko ze-neural tube:I-Folic acid ukwengeza ngesikhathi sokukhulelwa inganciphisa kakhulu ingozi yeziphetho ze-Fetal Neural tube iziphetho (njenge-spina bifida ne-amencephaly), abesifazane abakhulelwe bavame ukwelulekwa ukuthi bangeze nge-folic acid.
3. Ukusekela i-Erythropoietis:I-Folic acid isiza ukwakheka kwamangqamuzana abomvu egazi futhi ivimbela i-anemia, ikakhulukazi i-megaloblastic anemia.
4. Khuthaza impilo yenhliziyo: I-Folic acid isiza amazinga aphansi ama-homocysteine futhi ingasiza ukunciphisa ingozi yesifo senhliziyo.
5. Ithuthukisa impilo yengqondo:Ezinye izifundo zibonisa ukuthi i-folic acid ingahle ibe nemiphumela emihle kwimood nempilo yengqondo futhi ingasiza ukunciphisa izimpawu zokudangala.
6. Thuthukisa ukusebenza komzimba:I-Folic acid nayo idlala indima ebalulekile emsebenzini ojwayelekile wamasosha omzimba futhi isiza ukuthuthukisa izivikeli zomzimba.
Beka kafushane
Amaconsi e-Folic acid ayisengezo esibalulekile sokudla okunempilo, ikakhulukazi kwabesifazane abakhulelwe nabesifazane abahlela ukukhulelwa, okungasekela ukuthuthukiswa okunempilo kwesibeletho, bavikele iziphambeko, futhi babe nezinzuzo eziningi zempilo yonke. Lapho usebenzisa, kunconywa ukulandela ukuholwa ngudokotela ukuqinisekisa ukuphepha nokusebenza ngempumelelo.
Isicelo
Ukusetshenziswa kwamaconsi e-folic acid kugxile kakhulu kulezi zinto ezilandelayo:
1. Ukunakekelwa kokukhulelwa:
Vikela amaphutha we-neural tube: I-Folic acid iyizakhi ezibaluleke kakhulu kwabesifazane abakhulelwe ngaphambi nangesikhathi sokukhulelwa kusenesikhathi, ezinganciphisa ngempumelelo ingozi yeziphetho ze-Fetal Neural Tube (njenge-anesphaly).
Ukugqugquzela ukuthuthukiswa kwe-fetus: I-Folic acid inomthelela ekukhuleni okujwayelekile kanye nentuthuko ye-fetus, ukusekela ukuhlukaniswa kweseli kanye nokuhlanganiswa kwe-DNA.
2. Thuthukisa i-anemia:
Ukwelashwa kwe-megaloblastic anemia: amaconsi e-folic acid angasetshenziselwa ukwelapha i-anemia ebangelwa ukuntuleka kwe-folic acid futhi asize ukuthuthukisa impilo yegazi.
3. Impilo yenhliziyo:
Yehlisa amazinga we-homocysteine: I-Folic acid isiza amazinga aphansi ama-homocysteine egazini, ngokunciphisa ingozi yesifo senhliziyo.
4. Ixhasa amasosha omzimba:
Ikhulisa ukusebenza komzimba: I-Folic acid idlala indima ebalulekile ekuhlukaniseni iseli nokukhula futhi isize ukugcina umsebenzi ojwayelekile wamasosha omzimba.
5. Impilo yengqondo ethuthukisiwe:
Isekela i-Nervous System Health: I-Folic acid ibalulekile empilweni yohlelo lwezinzwa futhi ingasiza ukuthuthukisa umsebenzi wokuqonda kanye nomsebenzi wokuqonda.
Umsebenzi
Amaconsi e-Folic acid avame ukuthathwa ngomlomo. Ukusetshenziswa okuqondile kanye nomthamo kufanele kulandele imiyalo yomkhiqizo noma izeluleko zikadokotela.
Amanothi
Ngaphambi kokusebenzisa amaconsi e-folic acid, kunconyelwa ukubonana nodokotela, ikakhulukazi kwabesifazane abakhulelwe, abesifazane abancelisa abebele kanye nabantu abanezimo zempilo ezikhethekile.
Ukudla ngokweqile kwe-folic acid kungavimba izimpawu zokuntuleka kwevithamini B12, ngakho-ke kufanele kusetshenziswe ngaphansi kokuholwa ngudokotela.
Beka kafushane
Amaconsi e-Folic acid ayisengezo esibalulekile sokudla, esetshenziswa kabanzi ekunakekelweni kokukhulelwa, ukwelashwa kwe-anemia, impilo yenhliziyo, kunconywa ukuthi kulandelwe ukuholwa kochwepheshe ukuqinisekisa ukuphepha kanye nokusebenza ngempumelelo.
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