I-N-Acetylneuraminic acid powder Umkhiqizi I-Newgreen N-Acetylneuraminic acid Supplement
Incazelo Yomkhiqizo
I-N-acetylneuraminic acid (i-NANA, i-Neu5Ac) iyingxenye enkulu yama-glycoconjugates, njenge-glycolipids, glycoprotein, nama-proteoglycans (sialoglycoproteins), anikeza isici sokubopha okukhethekile kwezingxenye ze-glycosylated. I-Neu5Ac isetshenziselwa ukutadisha i-biochemistry, i-metabolism kanye nokuthatha kwayo ku-vivo kanye ne-in vitro. I-Neu5Ac ingasetshenziswa ekuthuthukiseni ama-nanocarriers.
I-COA
| Izinto | Imininingwane | Imiphumela | |
| Ukubukeka | Impushana emhlophe | Impushana emhlophe | |
| Isivivinyo |
| Dlula | |
| Iphunga | Lutho | Lutho | |
| Ukuminyana Okuxekethile(g/ml) | ≥0.2 | 0.26 | |
| Ukulahlekelwa Ekumisweni | ≤8.0% | 4.51% | |
| Izinsalela ekushiseni | ≤2.0% | 0.32% | |
| PH | 5.0-7.5 | 6.3 | |
| Isilinganiso sesisindo samangqamuzana | <1000 | 890 | |
| Izinsimbi Ezisindayo(Pb) | ≤1PPM | Dlula | |
| As | ≤0.5PPM | Dlula | |
| Hg | ≤1PPM | Dlula | |
| Ukubalwa Kwamagciwane | ≤1000cfu/g | Dlula | |
| I-Colon Bacillus | ≤30MPN/100g | Dlula | |
| Imvubelo & Isikhunta | ≤50cfu/g | Dlula | |
| Amagciwane e-Pathogenic | Okubi | Okubi | |
| Isiphetho | Vumelanisa nencazelo | ||
| Impilo yeshelufu | Iminyaka emi-2 lapho igcinwe kahle | ||
Umsebenzi
1. Thuthukisa ubuhlakani nenkumbulo yengane
I-N-Acetylneuraminic acid iyisakhiwo esibalulekile sama-gangliosides ebuchosheni. Okuqukethwe yi-asilic acid kulwelwesi lwezinzwa kuphindwe izikhathi ezingama-20 kunamanye amaseli. Ngoba ukudluliswa kolwazi lobuchopho kanye nokuqhutshwa kwemizwa yezinzwa kufanele kubonakale ngokusebenzisa ama-synapses, futhi i-N-Acetylneuraminic acid iyisakhi sobuchopho esisebenza ku-membrane yamangqamuzana obuchopho kanye nama-synapses, ngakho-ke i-N-Acetylneuramininic acid ingakhuthaza Ukuthuthukiswa kwenkumbulo nokuhlakanipha. Ucwaningo luye lwathola ukuthi ukwandisa okuqukethwe kwe-N-Acetylneuraminic acid ekudleni kokuncelisa kuzokwandisa okuqukethwe kwe-N-Acetylneuraminic acid ebuchosheni bengane, futhi izinga lokukhuluma lezakhi zofuzo ezihlobene nokufunda nalo lizokhula, ngaleyo ndlela lithuthukise amakhono ayo okufunda nenkumbulo. Ezinganeni, okuqukethwe kwe-N-Acetylneuraminic acid kungamaphesenti angama-25 kuphela obisi lwebele.
2. I-anti-senile dementia
I-N-Acetylneuraminic acid inomphumela wokuvikela nokuzinza kumaseli wezinzwa. Ngemuva kokuthi i-protease etholakala ebusweni be-nerve cell membrane ihlanganiswe ne-N-Acetylneuraminic acid, ayinakucekelwa phansi yi-extracellular protease. Ezinye izifo ze-neurological, ezifana ne-senile dementia kanye ne-schizophrenia, zizonciphisa okuqukethwe kwe-N-Acetylneuraminic acid egazini noma ebuchosheni, futhi ngemva kokululama ekwelashweni kwezidakamizwa, okuqukethwe kwe-N-Acetylneuraminic acid kuzobuyela kokujwayelekile, okubonisa ukuthi i-N-Acetylneuraminic acid ibamba iqhaza. enqubweni ye-metabolic yamangqamuzana ezinzwa .
3. Ukungahlonishwa
Phakathi kwama-molecule namaseli, phakathi kwamangqamuzana namangqamuzana, naphakathi kwamangqamuzana nezwe langaphandle, i-N-Acetylneuraminic acid ekugcineni kochungechunge loshukela ingasebenza njengendawo yokuqaphela noma imaski indawo yokuqaphela. I-N-Acetylneuraminic acid exhunywe ekupheleni kwe-glycosides ngokusebenzisa izibopho ze-glycosidic ingavimbela ngokuphumelelayo ezinye izingosi ezibalulekile ze-antigenic kanye nezimpawu zokuqaphela endaweni yeseli, ngaleyo ndlela ivikele lawa ma-saccharides ukuba angabonwa futhi awonakaliswe amasosha omzimba azungezile.
Izinhlelo zokusebenza
1. I-N-Acetylneuraminic acid isetshenziswa ekukhiqizeni ama-neuraminidase inhibitors ahlukahlukene, ama-glycolipids kanye neminye imikhiqizo ye-bioactive eyenziwe ngokwenziwa. Ingasetshenziswa njengesengezo sokudla okunomsoco.
2. I-N-Acetylneuraminic acid idlala indima ebalulekile ekwengezeni kokudla njenge-glyconutrient. Ilawula isigamu sempilo yamaprotheni egazi, i-acidification, i-neutralization yobuthi obuhlukahlukene, ukunamathela kwamaseli kanye nokuvikelwa kwe-glycoprotein lysis. Ingasetshenziswa njengesengezo sokudla.
3. I-N-Acetylneuraminic acid ingasetshenziswa njenge-reagent yokuqala yokuhlanganiswa kwe-biochemical derivatives yezidakamizwa. Ingasetshenziswa njenge-cosmetic.
Iphakheji Nokulethwa
