Hydroxypropyl Beta Cyclodextrin CAS 128446-35-5 hydroxypropyl-β-cyclodextrin
ọja apejuwe
Hydroxypropyl beta-cyclodextrin jẹ agbo-ara ti o wọpọ ti a lo gẹgẹbi oluranlọwọ ninu awọn eto ifijiṣẹ oogun. Ni aaye iṣoogun, o ni awọn ipa wọnyi:
Imudara isokuso oogun: Hydroxypropyl β-cyclodextrin le ṣe agbekalẹ awọn eka ifisi pẹlu diẹ ninu awọn oogun insoluble, mu ilọsiwaju oogun ati iduroṣinṣin pọ si, ati mu gbigba oogun ati bioavailability pọ si.
Ṣe ilọsiwaju iduroṣinṣin oogun: Hydroxypropyl β-cyclodextrin le daabobo diẹ ninu awọn oogun ti o ni irọrun ni ipa nipasẹ ina, ooru, atẹgun ati awọn ifosiwewe miiran, jijẹ iduroṣinṣin ati igbesi aye selifu ti awọn oogun.
Imudara itọwo: Hydroxypropyl β-cyclodextrin le boju-boju diẹ ninu awọn itọwo buburu gẹgẹbi kikoro ati ekan ti oogun, mu itọwo dara, ati jẹ ki oogun naa rọrun lati gba ati lo.
Idinku majele: Hydroxypropyl β-cyclodextrin le jẹ ibajẹ nipasẹ eto enzymu ninu ara sinu awọn nkan ti ko lewu ti o le yọkuro, eyiti o le dinku majele ati awọn ipa ẹgbẹ ti awọn oogun lori ara eniyan. Ni afikun si ohun elo ni aaye oogun, hydroxypropyl β-cyclodextrin tun jẹ lilo pupọ ni ounjẹ, awọn ohun ikunra ati awọn aaye miiran lati ni ilọsiwaju solubility, iduroṣinṣin ati itọwo.
Ounjẹ
Ifunfun
Awọn capsules
Ilé iṣan
Awọn afikun ounjẹ ounjẹ
Išẹ
Hydroxypropyl β-cyclodextrin jẹ moleku suga cyclic ati oluranlowo encapsulating molikula olomi-omi. O ni orisirisi awọn iṣẹ, pẹlu:
1.Solubilization: Hydroxypropyl β-cyclodextrin le mu ilọsiwaju ti awọn oogun ti a ko le yanju daradara ati igbelaruge itu wọn ninu omi, nitorina imudarasi bioavailability wọn.
2.Enhanced iduroṣinṣin: Hydroxypropyl β-cyclodextrin le daabobo awọn ohun elo oogun ti o ni imọlara lati ibajẹ nipasẹ awọn ifosiwewe ayika bii ina, atẹgun, ati iwọn otutu, ati mu iduroṣinṣin oogun ati igbesi aye selifu.
3.Encapsulation: Hydroxypropyl β-cyclodextrin le ṣe iyipada awọn ohun ti o wa ni aiduro, iyipada, tabi awọn ohun-ọrun ti ko dara ninu rẹ nipasẹ imudani ti molikula, nitorina imudarasi iduroṣinṣin rẹ ati iriri olumulo.
4.Taste-masking: Hydroxypropyl beta-cyclodextrin le ma ndan kikoro, pungent tabi awọn ohun elo oogun ti ko dun lati mu itọwo oogun ati gbigba alaisan dara.
5.Drug Ifijiṣẹ: Hydroxypropyl β-cyclodextrin le mu imudara ati pinpin awọn oogun sinu ara nipasẹ jijẹ solubility omi ati iduroṣinṣin ti awọn ohun elo oogun, nitorinaa imudara ipa ti awọn oogun.
Ohun elo
Hydroxypropyl β-cyclodextrin jẹ oluranlowo encapsulating molikula multifunctional ti o le mu solubility, iduroṣinṣin, itọwo ati ifijiṣẹ oogun, ati pe o lo pupọ ni oogun, ounjẹ, awọn ohun ikunra ati awọn aaye miiran.
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