I-Ticagrelor Newgreen Supply APIs 99% yeTicagrelor Powder
Ingcaciso yeMveliso
I-Ticagrelor yi-antiplatelet drug, i-P2Y12 i-receptor antagonist, esetyenziselwa ngokukodwa ukukhusela iziganeko ze-cardiovascular, ngakumbi kwizigulane ezine-acute coronary syndrome (ACS). Iyanciphisa umngcipheko we-thrombosis ngokuthintela ukuhlanganiswa kweplatelet.
Oomatshini abaphambili
Nqanda ukudityaniswa kweeplatelet:
I-Ticagrelor ibophelela ngokubuyisela kwi-P2Y12 i-receptor kwi-platelet surface, inqanda ukusebenza kweplatelet kunye nokuhlanganiswa okubangelwa yi-adenosine diphosphate (ADP), ngaloo ndlela inciphisa ukubunjwa kwe-thrombus.
Iimpawu
I-Ticagrelor isetyenziswa ikakhulu kwezi meko zilandelayo:
I-Acute Coronary Syndrome:Kubandakanya izigulane ezine-angina engazinzanga kunye ne-myocardial infarction, edla ngokusetyenziswa ngokudibanisa ne-aspirin ukunciphisa umngcipheko weziganeko ze-cardiovascular.
Uthintelo lwesibini lweziganeko zentliziyo:Kwizigulane esele zinesiganeko se-cardiovascular ukukhusela esinye.
I-COA
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo omhlophe | Iyahambelana |
| Umyalelo | Uphawu | Iyahambelana |
| Isivavanyi | ≥99.0% | 99.8% |
| Wangcamla | Uphawu | Iyahambelana |
| Ilahleko ekomisweni | 4-7(%) | 4.12% |
| IAsh iyonke | 8% Ubuninzi | 4.85% |
| Intsimbi enzima | ≤10(ppm) | Iyahambelana |
| Arsenic(As) | 0.5ppm Ubuninzi | Iyahambelana |
| Khokela(Pb) | 1ppm Max | Iyahambelana |
| IMercury(Hg) | 0.1ppm Max | Iyahambelana |
| Ukubalwa kwePleti iyonke | 10000cfu/g Ubuninzi. | 100cfu/g |
| Igwele kunye noMngundo | 100cfu/g Ubuninzi. | ＞20cfu/g |
| Salmonella | Ibi | Iyahambelana |
| E.Coli. | Ibi | Iyahambelana |
| Staphylococcus | Ibi | Iyahambelana |
| Ukuqukumbela | Ufanelekile | |
| Ugcino | Gcina kwindawo evaliweyo kunye neqondo lokushisa eliphantsi rhoqo kwaye akukho kukhanya kwelanga ngqo. | |
| Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo | |
Imiphumela
I-Ticagrelor ngokuqhelekileyo inyamezeleke kakuhle, kodwa ezinye iziphumo zecala zingenzeka, kuquka:
Ukopha:Esona siphumo sixhaphake kakhulu, esinokubangela ukopha okungephi okanye kubi kakhulu.
Ubunzima bokuphefumla:Ezinye izigulana zinokuba nobunzima bokuphefumla okanye ukukhohlela.
Iimpendulo zesisu:ezifana nesicaphucaphu, iintlungu zesisu okanye ukungagayi ngokwaneleyo.
Amanqaku
Umngcipheko Wokopha:Umngcipheko wokuphuma kwegazi kufuneka ubekwe iliso rhoqo xa usebenzisa i-Ticagrelor, ngakumbi xa isetyenziswe ngokuhambelana namanye amachiza e-anticoagulant.
Umsebenzi weHepatic:Ukusetyenziswa ngokuqaphela kwizigulane ezine-hepatic impairment; ukulungiswa kwethamo kunokufuneka.
Ukusebenzisana kweziyobisi:I-Ticagrelor inokusebenzisana namanye amachiza. Kufuneka uxelele ugqirha wakho malunga nazo zonke iziyobisi ozithathayo ngaphambi kokuba uyisebenzise.
Ukupakishwa kunye nokuhanjiswa
