Kwiminyaka yakutshanje, into ebizwaNicotinamide Riboside(NR) iye yatsala ingqalelo ebanzi kwindawo yenzululwazi kunye necandelo lezempilo. I-NR yi-precursor ye-vitamin B3 kwaye ithathwa njengento yokuchasana nokuguga kunye nokhathalelo lwempilo, kwaye iba yindawo eshushu yophando kunye nophuhliso.
NRkufunyaniswe ukunyusa amanqanaba e-intracellular e-NAD +, i-coenzyme ebalulekileyo ebandakanyekayo ekulawuleni imetabolism yeselula kunye nokuveliswa kwamandla. Njengoko iminyaka ikhula, amanqanaba e-NAD + emzimbeni womntu ehla kancinci, kwaye ukongezwa kwe-NR kunokunceda ukugcina amanqanaba aphezulu e-NAD +, ekulindeleke ukuba alibazise inkqubo yokuguga kunye nokuphucula ukusebenza kweeseli.
Ukongeza kumandla ayo okuthintela ukwaluphala,NRifunyenwe ineziphumo ezilungileyo kwimpilo ye-cardiovascular, impilo ye-metabolic, kunye ne-neuroprotection. Uphando lubonisa ukuba i-NR inokuphucula umsebenzi wemithambo yegazi, amanqanaba asezantsi e-cholesterol, ukunciphisa iimpendulo ezivuthayo, kwaye ineenzuzo ezinokubakho ekuthinteleni isifo sentliziyo. Ukongeza, i-NR ikholelwa ukuba inceda ukulawula amanqanaba eswekile yegazi, ukuphucula ukuvalelwa kwe-insulin, kunye nokudlala indima ekuthinteleni isifo seswekile kunye nokukhuluphala. Ngokubhekiselele kwi-neuroprotection, i-NR ifunyenwe yokuphucula ukuveliswa kwamandla kweeseli zengqondo kwaye kulindeleke ukuba idlale indima efanelekileyo ekuthinteleni izifo ze-neurodeergenerative.
Njengoko uphando kwi-NR luqhubeka lunzulu, iinkampani ezininzi zeemveliso zempilo ziqala ukongeza i-NR njengesithako esiphambili kwiimveliso zempilo ukuhlangabezana neemfuno zabantu zokuchasa ukuguga kunye nokhathalelo lwempilo. Ngaxeshanye, ezinye iimvavanyo zeklinikhi nazo ziyaqhubeka ukuqinisekisa ukusebenza kunye nokhuseleko lwe-NR kwiinkalo ezahlukeneyo zempilo.
NangonaNRinamandla amakhulu, uphando oluninzi luyafuneka ukuze kuqinisekiswe iziphumo zalo zexesha elide kunye nokhuseleko. Ukongeza, abantu nabo kufuneka bakhethe iimveliso ze-NR ngononophelo ukuze baqinisekise ukuba imithombo kunye nomgangatho wabo uthembekile. Njengoko uphando kunye nophuhliso lwe-NR luqhubeka lunzulu, ndiyakholelwa ukuba luya kuzisa impumelelo entsha kunye nethemba kwimpilo yabantu.
Ixesha lokuposa: Aug-29-2024
