Yintoni iI-resveratrol?
I-resveratural yindawo yendalo efumaneka kwizityalo ezithile, iziqhamo kunye newayini ebomvu. Yeyona qela leentambo ezibizwa ngokuba yipolyphenols, ezazisebenza njengeotioxidants kwaye zaziwa ngezibonelelo zazo zempilo. I-resveratrol ininzi kakhulu kulusu lweediliya ezibomvu kwaye ibingumxholo wezifundo ezininzi ngenxa yeziphumo zayo ezinokubakho kwiinkalo ezahlukeneyo zempilo.
Olunye uphando lubonisa ukuba i-resveratratrol inokuba nezibonelelo ezinokubakho ngempilo yentliziyo, njengoko inokunceda inkxaso imithambo yegazi kunye nokujikeleza. Ukongeza, ifundwe ngenxa yokulwa kwayo i-anti-insulmatory kunye neepropathi ze-antioxidant, ezinokuba nefuthe kwiinkqubo zempilo nezaluphekayo.
I-resveratrateral ikwaphandwa ngendima yayo enokubakho ekuxhaseni ukusebenza kwengqondo kunye nokusebenza kwengqondo, kunye neziphumo zayo kwi-metabolism kunye nezibonelelo ezinokubakho kulawulo lobuninzi.
Ipropathi yomzimba kunye nekhemikhali ye-resveratsasa
I-resveratrarol (3-4'-5-Trizddroxystilbene) yindawo engeyiyo i-polyphenol polyphenol ye-polyphenol. Igama lekhemikhali lekhemikhali ngu-3,4 ', 5-trihydroxy-1,2-diphenyethylene (3,4', i-5-trihydrokystilbene), ifomula yemolekyuli yi-C13, kwaye ubunzima bayo bemolekyuli bungama-228.25.
I-resveratrol ecocekileyo ibonakala njengemhlophe ukuba ibe ngumgubo ophuzi ophuzi, ongenakubulawa, kwaye inyibilikiswe ngokulula kwiinyibiliki, i-chlorol, ethanol, ne-ethanol, kunye ne-ethyl acetate. Inqaku lokunyibilika lingama-253-255 ° C, kwaye ubushushu obunqabileyo bungama-261 ° C. Ingaguqula i-Alkaline Solutions ezinje nge-Ammonia amanzi, kwaye inokusabela nge-ferric chloric ferrocyanide. Le propati inokusetyenziselwa ukukhangela i-resveratrol.
I-Redsveratrol yendalo inamacandelo amabini, i-cis kunye ne-trans. Kukuphakathi kwe-trans uthontelotion kwindalo. Ezi zinto zimbini zinokudityaniswa ne-glucose yokwenza i-cis kunye ne-trans resveratrol gelycossides. I-CIS-kunye ne-trans-resveratrol gelycossides inokukhupha i-resveratrorol phantsi kwesenzo se-glycosidase kwithumbu. Ngaphantsi kokukhanya kwe-ultraviolet, i-trans-resvesveratrol inokuguqulwa ibe yi-cis-isomers.
Indlela yokulungiselela
Indlela yendalo yokukhuphela
Iidiliya, i-knotweed kunye ne-peanuts zisetyenziswa njengezinto eziluhlaza okukhuphayo kunye ne-resveratrol eyahlukileyo, emva koko icoceke. Itekhnoloji yokukhuthaza i-caude ephambili ibandakanya ukuthunyelwa kweShorvent, iAlkaline yokukhupha kunye nokukhutshwa kwe-enzyme. Iindlela ezintsha ezinjenge-microwave-incedisi lokukhutshwa kwe-microwave, i-CO2 ye-CO2 ebalaseleyo kunye nokukhutshwa kwe-Ultrasonic-anced kuya kusetyenziswa. Injongo yokuhlanjululwa ikakhulu ukwahlula i-cis-ne-trans-isomers ye-resveratratral kunye ne-resveratrarol evela kwi-cruderalrol ye-crude ukuya kufumana i-transferal. Iindlela zokucoca eziqhelekileyo ziquka i-chromatography, i-Silica Gel Compacloction Chromatography, i-Maner romatography, i-chromatography ye-chromatography, njl.
Indlela ye-synthesis
Ukusukela okoi-resveratrolKwizityalo eziphantsi kakhulu kwaye iindleko zokukhupha ziphezulu, ukusetyenziswa kweekhemikhali, ubunjineli bebhayoloji, ubunjineli bendalo kunye nezinye iindlela zokufumana i-resveratrol ibe yinto ebalulekileyo kwinkqubo yayo yophuhliso. Ukuphendula kwe-Perkin, ukusabela kwe-Pech, kunye nokuphendula kweHet-rormer yindlela evuthiweyo yekhemikhali yokuvumela i-resveratrol, ngesivuno se-55.2%, kunye ne-35.7% ngokwahlukeneyo. Itekhnoloji yobunjineli bemfuza isetyenziselwa ukulawula okanye ukuphucula indlela yeBioSynthelis yendlela ye-resveratralrol ukufumana ubunzima obuphezulu; Iindlela ezifana nokusebenzisa i-mutagednesis ukukhetha imigca yeseli ephezulu yokonyusa isivuno se-resveractrol ngamaxesha angama-1.5 ~ 3.0.
Yintoni isibonelelo seI-resveratrol?
I-resveratrarol ibingumbandela wophando ngenxa yezibonelelo zempilo ezinokubakho. Ezinye zeenzuzo ezinokubakho ze-resveratsetsasazi:
I-1.ntiyi-ubudala
Ngo-2003, uNjingalwazi weYunivesithi yaseHarvard UDavid Siclair kunye neqela lakhe bafumanisa ukuba i-resveratrarol inokuvula i-acetylase kwaye yandise ixesha lokuphila, elibalekayo kuphando oluchasene ne-andationralrol. Howtz et al. Ifunyenwe ukuba i-resveratral inokusebenza njengeyona nto inamandla yommiselo wolwazi we-2 yeHomolog1 (i-SIRT1), inokulinganisa impendulo yokulwa i-allorie ye-calorie ye-calorie (CR), kwaye ithathe inxaxheba kwimigangatho yezinto eziphilayo. . I-CR yelondolozo eqinileyo lodaka, kwaye inokunyusa ukubonakaliswa kwe-stirt1 kwizibonda kunye nezicubu ezinjengengqondo, intliziyo, izintso, imisipha, izintso, imisipha. I-CR CR inokubangela utshintsho lomzimba oluyandisa ukwaluphala kwaye lwandise i-Lifepan, eyona nto ibalulekileyo enokwandiswa nge-50%. . Izifundo ziqinisekisile ukuba i-resveratsasa inokuthi yongeze ixesha lokuphila, ii-nematode, iimpukane zeziqhamo kunye neentlanzi ezisezantsi.
I-2.ntii-Tumor, i-anti-umhlaza
I-resveratsol ineempembelelo ezibalulekileyo ze-tumor kwiiseli ezahlukeneyo ze-tumor efana ne-hepatocellinal ye-hepatoni, umhlaza wamabele, umhlaza wekholoni, umhlaza we-colon, kunye noLeukemia. Abanye abafundi baqinisekisile ukuba i-resveratsasa inesiphumo esibalulekileyo kwi-Melanoma iiseli ngendlela ye-MTT kunye ne-cytometry.
Kukho iingxelo ezinokuthi i-resveraturatrol inokuphucula umhlaza radiotheratheratherapy kwaye ithintele ngokufanelekileyo imiphumo yeeseli zomhlaza. Kodwa ukuza kuthi ga ngoku, ngenxa yobunzima be-resveratral's ye-anti-tumaratis, abaphandi abakafiki kwimvumelwano malunga nendlela yayo yesenzo.
3.opilive kwaye uphathe isifo sentliziyo
Uhlobo lwezifundo zefobhuleni ufumene ukuba i-paradome ye "French Pradomen yinto yokuba abantu baseFrance batya amanqatha amakhulu yonke imihla, kodwa izehlo kunye nokusweleka kwamanye amazwe. Le phenomenon inokuhambelana nokusetyenziswa kwabo kwemihla ngemihla kwewayini enkulu yewayini. , kwaye i-resveratratrarol inokuba yiyona nto iphambili ikhuthazayo. Uphando lubonisa ukuba i-resveraturatral inokulawula amanqanaba e-cholesterol yegazi ngokubophelela kwimizimba yomzimba, ethintele iiplates ezivela kwisifo seentliziyo, kwaye sinciphise umngcipheko wesifo sentliziyo emzimbeni womntu. Umngcipheko wesifo se-vascular.
Inkxaso ye-4nisoxidant:I-resveratrolIzenzo njengomlinganiso, ukunceda ukukhusela iiseli zomonakalo obangelwe yi-radicals yasimahla. Oku kunokuba nefuthe kwiinkqubo zempilo kunye neenkqubo zokwaluphala.
6. Impilo yengqondo: Uphando luphonononge lendima ye-resveratsiral ekuxhaseni ukusebenza kwengqondo kunye nokusebenza kwengqondo, kunye nezinye izifundo ziphakamisa iipropathi ze-neuroproprocetive.
7.mettabolism kunye nolawulo lobunzima: I-resveratrateratrateratrateratset iphandwe ngeziphumo zayo ezinokubakho kwiMetabolism kunye nendima yazo ekuxhaseni ulawulo olusempilweni.
Zithini izicelo zeI-resveratrol?
I-resveratrarol ineenkqubo ezahlukeneyo kwaye isetyenziswa kwimihlaba eyahlukeneyo ngenxa yezibonelelo zempilo ezinokubakho. Ezinye zezicelo ze-resveratsetsetsetsetsetsetsetset
I-1. Izongezo zokutya: I-Redsverature isetyenziswa rhoqo kwizongezo zokutya, zihlala zithengiswa ngenxa yeepropathi zayo ze-antioiyoxidant kunye ne-anti-agagu.
2. Iimveliso ze-Skercare: I-StorCaratsasayiwa ifakwe kwiimveliso ezithile zolusu ngenxa yeepropathi zayo ze-antioxidant, ezinokunceda ukukhusela ulusu kwingozi yokusindisa isisiseko kunye nenkxaso impilo yolusu.
3. Ukutya okusebenzayo kunye neZiselo: I-Redsveratsasa ngamanye amaxesha yongezwe kukutya kunye neziselo, ezinjengeziselo zamandla kunye neemveliso zokutya ezempilo, ukubonelela ngezibonelelo zempilo ezijolise kuzo.
4. Uphando kunye nophuhliso: I-resveratratrarol iyaqhubeka nokuba ngumxholo wophando lwezesayensi, kunye nezifundo eziqhubekayo zikhangela izicelo zayo ezinokubakho kwiimeko ezahlukeneyo zempilo kunye neziphumo zalo ekwenzeni intlalo-ntle.
Yintoni eyona nto iphambili kwi-resveraterol?
Ngelixa i-resveratratral ifundwe ngenxa yezibonelelo zempilo ezinokubakho, kubalulekile ukuqwalasela iindawo ezinokubakho okanye ukunqongophala okunxulumene nokusetyenziswa kwayo. Abanye baqwalaselwa malunga ne-Dowside ye-resveratseratrol ibandakanya:
I-1. I-bioaaif i-bioaint: i-resveratratrol ine bhadiafayishini ephantsi, intsingiselo yokuba umzimba awunakuyifumana kwaye ayisebenzise ngokufanelekileyo xa kuthathwa ngomlomo. Oku kunokuchaphazela ukusebenza kwayo ekuveliseni iziphumo zempilo ezinqwenelekayo.
2. Ukunqongophala kokubekwa emgangathweni: Umgangatho kunye noxinzelelo lwezongezo ze-resveractrol ziyahluka, kwaye kukho ukungabikho kokubekwa emgangathweni ekuvelisweni kwezi zinto zongezo. Oku kunokwenza kube nzima abathengi ukuba bamisele idosi efanelekileyo kunye nomgangatho wemveliso.
3. Unxibelelwano olunokubakho: I-resveratsasa inokunxibelelana namayeza athile okanye kwiimeko zempilo. Kubalulekile ukuba unxibelelane noxinzelelo lwezempilo ngaphambi kokuba usebenzise i-resveratseratser, ngakumbi ukuba uthatha amanye amayeza okanye unenkxalabo ethile yezempilo.
4. Imida yoPhando: Ngelixa ezinye izifundo zibonise iziphumo ezithembisayo, kufuneka uphando ngakumbi ukuze uqonde ngokupheleleyo iziphumo zexesha elide, idosi efanelekileyo, kunye nengozi ezinokubakho kwi-resverancel eyongezelelweyo.
Njengayo nayiphi na eyongezelelweyo, kuyacetyiswa ukuba kusetyenziswe i-resveratralrol ngononophelo naphantsi kwesikhokelo sezempilo, ngakumbi ukuba unenkxalabo ethile yezempilo okanye uthatha amanye amayeza.
Imibuzo ehambelana nayo unokunomdla kwi:
Ngubani na omele aphephei-resveratrol?
Abanye abantu kufuneka balumke okanye baphephe i-resveratroli, ngakumbi kwifom yongezo egxile. Kucetyiswa ukuba la maqela alandelayo abonisane nezempilo ekusebenzeni kwezempilo ngaphambi kokusebenzisa i-resveratch:
I-1. Ukukhulelwa okanye ukhulelwe abafazi
2. Abantu abathatha impahla yegazi: i-resveratral inokuba nepropathi yase-Anticouailant, ke abantu abathatha amayeza okudlala ngegazi kufuneka banxibelelane ne-Procied Speciedscaraticarat Presserat.
3. Abo baneemeko ezibuthathaka zehomoni: i-resveratsasazi ye-hormone ifundwe ngenxa yemigaqo ye-HORMONE, ukuze abantu abane-hormone-meko ezibutshekileyo okanye abaphantsi konyango lwehomoni kufuneka basebenzise i-resveratives kunye neliso lonyango.
4. Abantu abaneemeko zesibindi: Ezinye izifundo ziphakamise ukuba iidosi eziphezulu ze-resveratseratsetset zinokuba neziphumo kwiSibindi. Abantu abanemibandela yesibindi okanye abo bathatha amayeza achaphazela isibindi kufuneka basebenzise i-resveratratroline ngononophelo nangonyango lweliso.
Njengayo nayiphi na eyongezelelweyo, kubalulekile ukuba unxibelelane noxinzelelo lwezempilo ngaphambi kokuba usebenzise i-resveratseral, ngakumbi ukuba unenkxalabo ethile yezempilo, okanye uzithathele ingqalelo amayeza, okanye ube neemeko zempilo.
Ithini i-resveratral kulusu?
Kukholelwa ukuba inike izibonelelo ezininzi ezinokubakho kulusu, oluye lwakhokelela ekubeninjwa kwemveliso yolusu. Ezinye zempembelelo ze-resveratch kwi-suphu zinokubandakanya:
I-1. I-Antioiyoclant ukhuseleko: Izenzo ze-Anti Oku kunokuba kukukhusela ulusu kulwemonakaliso lwendalo, njengemitha ye-UV kunye nongcoliseko.
2. Iipropathi ezichasene nolwaluko: i-resveratratchs kucingelwa ukuba ineziphumo zokwaluphala, njengoko kunokunciphisa ukucofa imigca emihle kunye nemibimbi, kunye nokuphucula impilo yesikhumba, kunye nenkxaso yempilo yolusu.
I-3. I-Anti-I-Intimatmatory: I-Redsveratratol ifundwe ngenxa yepropathi yayo yokulwa ne-insuramatory, enokuthi incede itolike kwaye ithole ulusu, ngakumbi ulusu oluthathekileyo.
4. Ukukhanya kolusu
Kukuphi ukutya okuphezulu kwi-resveratraterol?
Ukutya okuphezulu kwi-resveratseratrateratratset:
1. Iidiliya ezibomvu: I-resveratrarol ininzi kakhulu kulusu lweediliya ezibomvu, zenza iwayini ebomvu kumthombo we-resveratsasa. Nangona kunjalo, kubalulekile ukuba utyelele utywala ngokumodareyitha, kwaye eminye imithombo ye-resveratsasa inokuthathwa kubangenzi.
I-2. I-Peansos: Iindidi ezithile ze-peanuts, ngakumbi ulusu lwe-peanut, zineemali ezibonakalayo ze-resveratsasa.
I-3. Iibluepries: Iiblueberries zaziwa ngomxholo wazo we-antioxidant, kwaye zinendawo yokuvuma, nangona zincinci ezithelekiswa neediliya ezibomvu kunye ne-peanuts.
4. Iingcibi: Iicrenberries zenye iMthombo ye-resesveratseral, ibonelela ngenani elithobekileyo leli candelo.
I-5. Itshokholethi emnyama: Ezinye iintlobo zetshokholethi ezimnyama ziqukethe i-resveratseral, ihambisa indlela emnandi yokufaka le quaw.
Kulungile ukuthatha i-resveratchrol yonke imihla?
Isigqibo sokuthatha i-resveratiral yonke imihla kufuneka senziwe ngokubonisana nengcali yezempilo, ngakumbi ukuba ithathela ingqalelo ukongeza i-resesveration. Ngelixa i-resveratsasa ithathelwa ingqalelo ngokubanzi xa ithethwe rhoqo kwiimali ezifumaneka ngokutya, izibonelelo zokuncedisa zemihla ngemihla zinokwahluka ngokusekwe kwimeko yezempilo, ekhoyo yonyango, kunye namanye amayeza athathiweyo.
Ngaba i-resveratrol iyingozi kwisibindi?
I-resveratral ifundwe ngenxa yempembelelo yayo enokubakho kwisibindi, kwaye ngelixa ithathelwa ingqalelo ngokubanzi xa ithethwe rhoqo xa ifumaneka rhoqo kukutya, kukho ubungqina obucacileyo bokuba amadoli aphezulu anokuba nefuthe kwiSibindi. Olunye uphononongo lubonise ukuba iidosi eziphakamileyo ze-resveratrarol zinokukhokelela kwityhefu yesibindi kwiimeko ezithile.
Kubalulekile ukuba uqaphele ukuba uphando malunga nesi sihloko luyaqhubeka, kwaye amandla otyhefu esibindi anokuphenjelelwa zizinto ezinjengemithango, ixesha lokusetyenziswa, kunye neemeko zempilo, kunye neemeko zempilo, kunye neemeko zempilo, kunye neemeko zempilo, kunye neemeko zempilo, kunye neemeko zempilo, kunye neemeko zempilo, kunye neemeko zempilo. Njengayo nayiphi na eyongezelelweyo, kuyacetyiswa ukuba inxibelelane nenkqubo yezempilo ngaphambi kokuba isebenzise i-resveratseral, ngakumbi ukuba unenkxalabo ethile yezempilo okanye uthatha amanye amayeza anokuchaphazela umsebenzi we-Silr.
Ngaba i-resvetveratrol imbi kwizintso?
Kukho ubungqina obulinganiselweyo ukucebisa ukuba i-resveratveral imbi kwizintso. Nangona kunjalo, njengayo nayiphi na eyongeziweyo, kubalulekile ukuba usebenzise i-sult, ngakumbi ukuba unemeko yezintso okanye ukuthatha amayeza anokuchaphazela umsebenzi wesintso. Kucetyiswa ukuba unxibelelane nengcali yezempilo ukufumanisa ukuba ingaba i-RERVECRORT ifanelekile kwiimfuno zempilo yakho, ngakumbi ukuba unezinto ezimbi ngefuthe lempilo yezintso.
Yintoni onokuyidibanisa nayoi-resveratrol?
Xa ujonga ukongeza i-resveratication, kubalulekile ukuba uyazi ukusebenza okunokubakho nezinye izinto. Abanye baqwalasela into esingayi kudibana ne-resveratseratrol ibandakanya:
I-1. Amayeza okudlala igazi: I-Redsveratratratol inokuba nepropathi enobulali, ke kubalulekile ukusebenzisa isilumkiso xa sithatha amayeza aphantsi kwegazi, njengoko enyusa umngcipheko wokophela.
2. Ezinye izongezelelo ze-Antioxidant: Ngelixa i-antioxidants ziyingenelo ngokubanzi, ukuthatha iidosi eziphezulu zezongezo ezininzi ze-antioxidant ngaxeshanye kunokuba nazo iziphumo ezingahlelwanga. Kucetyiswa ukuba unxibelelane nenkqubo yezempilo ngaphambi kokuba udibanise i-resveratrol kunye nezinye izinto ezongeziweyo ze-Antioxidant.
3. Amayeza athile: i-resveratsasa inokunxibelelana namayeza athile, kubandakanya nawo wamenzela isibindi. Kubalulekile ukuxoxa ngonxibelelwano olunokubakho ngengcali yempilo, ngakumbi ukuba uthatha amanye amayeza.
Njengayo nayiphi na eyongezelelweyo, kubalulekile ukuba ufune ukhokelo kwingcali yezempilo ukumisela olona hlobo lusetyenziswayo kwi-resveratrol esekwe kwimeko yezempilo nganye kunye nezinye izinto ezinokubakho zezempilo.
Ndingayisebenzisa iVitamin C nge-resveratralrol?
Ewe, unokusebenzisa i-vitamin c nge-resveratralrol. Ngapha koko, olunye uphando lubonisa ukuba ukudibanisa i-resveratveral kunye ne-Vitamin C kunokuphucula iziphumo ze-antioxidant zezinto zombini. I-Vitamin C ingumoyimo owaziwayo onokuthi agqibe izibonelelo ezinokubakho ze-resveratsasa. Nangona kunjalo, njengayo nayiphi na indibaniselwano yongezo, kuyacetyiswa ukuba inxibelelane nengcali yezempilo ukuqinisekisa ukuba ukudityaniswa kufanelekile kwiimfuno zempilo yakho kunye nokuxoxa malunga nokunxibelelana okanye ukuqwalaselwa.
Ixesha lasemva: Sep-09-2024
