Ukusuka kwindlela eqinisekisiweyo yokusebenza, i-NMN ikhethekileyoithuthwa kwiiseli nge-slc12a8 transporter kwiiseli zamathumbu amancinci, kwaye yonyusa inqanaba le-NAD+ kumalungu ahlukeneyo kunye nezicubu zomzimba kunye nokujikeleza kwegazi.
Nangona kunjalo, i-NMN iyancipha ngokulula emva kokuba umswakama kunye nobushushu bufikelele kubude obuthile. Okwangoku, uninzi lwe-NMN kwimarike iicapsules kunye neetafile. Emva kokuthatha i-NMN capsules okanye iipilisi,uninzi lwazo luthotywa esiswini, kwaye kuphela inxalenye encinci ye-NMN ifikelela kumathumbu amancinci.
● Yintoniliposomal NMN?
I-Liposomes "ziingxowa" ze-spherical ezenziwe ngee-molecule ze-dicyclic fatty acid ezibizwa ngokuba yi-phosphatidylcholine molecules (i-phospholipids eqhotyoshelwe kumasuntswana e-choline). I-Liposome spherical "sacs" ingasetyenziselwa ukufaka izongezo zesondlo ezifana ne-NMN kwaye zihanjiswe ngokuthe ngqo kwiiseli kunye nezicubu zomzimba.
Imolekyuli ye-phospholipid inentloko ye-hydrophilic phosphate kunye nemisila emibini ye-hydrophobic fatty acid. Oku kwenza i-liposome ibe ngumthwali we-hydrophobic kunye ne-hydrophilic compounds. I-Liposomes zi-lipid vesicles ezenziwe nge-phospholipids ezidityanisiweyo ukuze zenze i-membrane ephindwe kabini, kanye njengazo zonke iiseli zeseli emizimbeni yethu.
● Kwenzeka njaniliposome NMNukusebenza emzimbeni?
Kwinqanaba lokuqala lokusebenzisana kwe-liposome-cell,liposome NMN ibambelela kumphezulu weseli. Kolu bophelelo, i-liposome NMN ifakwe ngaphakathi kwiseli ngokusebenzisa i-endocytosis (okanye i-phagocytosis).Ukulandela ukugaya kwe-enzymatic kwikhompatimenti yeselula,I-NMN ikhutshelwa kwiseli, ukubuyisela umsebenzi wokuqala wesondlo.
Injongo yokuthatha nayiphi na isongezelelo kukuqinisekisa ukuba ingena egazini ngokusebenzisa i-mucous membranes kunye neeseli ze-epithelial zamathumbu. Nangona kunjalo, ngenxa yezinga eliphantsi lokufunxa kunye ne-bioavailability yeefom ze-NMN zemveli,isithako esisebenzayo silahlekelwa ngamandla aso amaninzi njengoko sidlula kwi-gastrointestinal tract, okanye ayifuntshwanga ngamathumbu amancinci.
Xa i-NMN idityaniswe ne-liposome, inceda ngakumbi ekuthuthweni kwe-NMN kwaye i-bioavailability iphuculwe kakhulu.
Ukuhanjiswa okujoliswe kuko
Ngokungafaniyo nazo zonke ezinye iindlela ze-NMN zokuhanjiswa kwe-morphological,liposomal NMNinomsebenzi wokukhulula ulibazisekile, okwandisa ixesha lokujikeleza kwezondlo eziphambili egazini kunye nokuphucula kakhulu i-bioavailability.
Ukuphakama kwe-bioavailability yento esebenzayo, inkulu impembelelo yayo emzimbeni.
Ukufunxa okuphezulu
Liposome NMNifunxwa ngeendlela ze-lymphatic kumgca we-mucosal womlomo kunye namathumbu;ukubetha i-metabolism yokuqala kunye nokubola kwesibindi,ukuqinisekisa ukugcinwa kwe-liposome NMN imfezeko. I-Synthesis yenziwa ukwenza i-NMN ibe lula ukuyihambisa kumalungu ahlukeneyo.
Oku kufunxa kuphezulu kuthetha ukusebenza kakuhle kunye needosi ezincinci kwiziphumo ezingcono.
Biocompatibility
Ifunyanwe kwiimbumba zeeseli kuwo wonke umzimba, i-phospholipids ikhona ngokwemvelo, kwaye umzimba uyaziqonda njengehambelana nomzimba kwaye ungababoni "njengetyhefu" okanye "yangaphandle" - kwaye ngoko ke,ayiqalisi uhlaselo lwe-immune ngokuchasene ne-liposomal NMN.
Ukufihla
Iiposomeskhusela i-NMN ekubonweni ngamajoni omzimba,ukulinganisa iifilimu zebhayoloji kunye nokunika isithako esisebenzayo ixesha elininzi lokufikelela kwindawo ekujoliswe kuyo.
I-Phospholipids ifihla izithako ezisebenzayo ukwenzela ukuba iimali ezininzi zifakwe kwaye zibaleke umsebenzi okhethiweyo wamathumbu amancinci.
Wela umqobo wegazi-ubuchopho
I-Liposomes ibonisiweukuwela umqobo wegazi-ubuchopho, eyenza i-liposomes ifake i-NMN ngokuthe ngqo kwiiseli kunye nokuphucula ukujikeleza kwezondlo ngenkqubo ye-lymphatic.
● Unikezelo ngeNMN yomgubo/iCapsules/Liposomal NMN
Ixesha lokuposa: Oct-22-2024
