I-Newgreen Supply High QualityBrown Algae Extract 98% Fucoidan Powder
Ingcaciso yeMveliso:
I-Fucoidan, eyaziwa ngokuba yi-fucoidan, i-fucoidan sulfate, i-fucoidan gum, i-fucoidan sulfate, njl., ubukhulu becala ukusuka kwi-algae emdaka, luhlobo lwepolysaccharide equkethe i-fucose kunye namaqela e-sulfuric acid. Inemisebenzi eyahlukeneyo yebhayoloji, efana ne-anti-coagulation, i-anti-tumor, i-anti-thrombus, i-anti-virus, i-anti-oxidation kunye nokuphucula umsebenzi wokuzikhusela komzimba, ngoko ke isetyenziswa kakhulu kwicandelo lamayeza kunye neshishini lokutya lanamhlanje. .
I-COA:
| Igama lemveliso: | Fucoidan | Umhla woVavanyo: | 2024-07-19 |
| Inombolo yeBatshi: | NG24071801 | Umhla wokuveliswa: | 2024-07-18 |
| Ubuninzi: | 450kg | Umhla WOKUPHELELWA: | 2026-07-17 |
| IZINTO | UMGANGATHO | IZIPHUMO |
| Imbonakalo | Mhlophe Poda | Vumelana |
| Ivumba | Uphawu | Vumelana |
| Ngcamla | Uphawu | Vumelana |
| Isivavanyi | ≥98.0% | 98.4% |
| Isiqulatho sothuthu | ≤0.2％ | 0.15% |
| Iintsimbi ezinzima | ≤10ppm | Vumelana |
| As | ≤0.2ppm | ＜0.2 ppm |
| Pb | ≤0.2ppm | ＜0.2 ppm |
| Cd | ≤0.1ppm | ＜0.1 ppm |
| Hg | ≤0.1ppm | ＜0.1 ppm |
| Ukubalwa kwePleti iyonke | ≤1,000 CFU/g | ＜150 CFU/g |
| Umngundo kunye negwele | ≤50 CFU/g | ＜10 CFU/g |
| E. Coll | ≤10 MPN/g | ＜10 MPN/g |
| Salmonella | Ibi | Ayifunyanwa |
| Staphylococcus Aureus | Ibi | Ayifunyanwa |
| Ukuqukumbela | Ukuhambelana neenkcukacha zemfuno. | |
| Ugcino | Gcina kwindawo epholileyo, eyomileyo kwaye engenamoya. | |
| Beka ubomi kwishelufa | Iminyaka emibini ukuba ivaliwe kwaye igcine kude nokukhanya kwelanga kunye nokufuma. | |
Umsebenzi:
1. Ukuphucula isifo sesisu
Kwafunyaniswa ukuba umphumo we-polysaccharide kwizifo zesisu wawubonakaliswe ngokukodwa kule miba mithathu ilandelayo: (1) I-polysaccharide inefuthe lokususa i-Helicobacter pylori, inqanda ukwanda kwe-Helicobacter pylori kunye nokuvimbela ukubopha kwayo nge-gastric mucosa; (2) Inefuthe lokukhusela i-gastric mucosa kunye nokunyanga isilonda sesisu, kwaye inefuthe elihle lokunciphisa utywala kunye neziyobisi ezibangelwa ukwenzakala kwe-gastric mucosal kunye nesilonda esingapheliyo esiswini; (3) I-Fucoidan inefuthe elichasayo lomhlaza wesisu, inokuthintela ukwanda kweeseli zomhlaza wesisu, ukunciphisa imiphumo emibi ye-chemotherapy, kunye nokuphucula umgangatho wobomi bezigulane.
2. Impembelelo ye-Anticoagulant
I-Fucoidan inemisebenzi emininzi yebhayoloji, kodwa umsebenzi wayo we-anticoagulant ngowona ufundwe ngokubanzi. Uphononongo lubonise ukuba i-polysaccharides ekhutshwe kwii-algae ezahlukeneyo zaseLwandle ezimdaka zinemigangatho eyahlukeneyo yokusebenza kwe-anticoagulant. Ngokomzekelo, i-polysaccharides evela kwaye ibonise iqondo eliphezulu lomsebenzi we-anticoagulant, kunye nomsebenzi we-anticoagulant kunye nesiqingatha sangaphambili, kodwa phantse akukho msebenzi we-anticoagulant.
3. Impembelelo ye-Antithrombotic
Kwimodeli yovavanyo yezilwanyana eziphilayo, i-polysaccharide ye-fucoidan inefuthe lokuthintela kuzo zombini i-venous thrombosis kunye ne-arterial thrombosis. Rocha et al. yafumanisa ukuba i-polysaccharide ayinayo umsebenzi we-anticoagulant kwi-vitro, kodwa ibonise umphumo ocacileyo we-antithrombotic kwimodeli yezilwanyana yokwenza i-venous thrombosis, kwaye umphumo wawuxhomekeke kwixesha, ufikelele kwi-8h yokulawula. Umsebenzi we-anticoagulant we-polysaccharide mhlawumbi wawunxulumene nokukhuthaza ukuveliswa kwe-heparin sulfate ngeeseli ze-endothelial.
4. Impembelelo ye-Antiviral
Uphononongo lubonise ukuba i-polysaccharides ene-sulfate (kubandakanywa ne-fucoidan polysaccharides) ibonisa umsebenzi we-antiviral zombini kwi-vivo kunye ne-vitro. UHayashi et al. wafunda umphumo wokukhusela we-fucoidan kwi-herpes simplex virus (HSV). Baye bafumanisa ukuba i-fucoidan inokukhusela iimpuku kusulelo lwe-HSV, kwaye yachaza ukuba i-fucoidan inokuthintela usulelo lwe-HSV ngokuthintela ngokuthe ngqo ukuphindaphinda kwentsholongwane kunye nokuphucula umsebenzi wokukhusela womzimba kunye nokufumana. Ngelo xesha, kwafunyaniswa ukuba i-polysaccharide ibonise umsebenzi we-antiviral ngokumelene ne-HSV-1 kunye ne-HSV-2. UHidari et al. ingxelo yokuba i-fucoidan inokuthintela ngokufanelekileyo usulelo lwentsholongwane ye-dengue 2 (DEN2), kwaye yabonisa ukuba i-fucoidan ibophelela kumasuntswana e-DEN2 kwaye isebenzisana nokupakishwa kwayo kwe-glycoprotein. Ayinayo impembelelo ye-passivation ngokuthe ngqo kwi-virions, kwaye indlela yayo ye-antiviral kukuthintela ukubunjwa kwe-cytiocytes ye-virus ngokuthintela i-adsorption ye-virus.
5. Impembelelo ye-Anti-tumor
I-Fucoidan ithathwa njenge-agent ye-anti-cancer yendalo, kwaye umsebenzi wayo wokulwa ne-tumor uchazwe ngakumbi nangakumbi. UAlekseyenko et al. wafunda umsebenzi ochasayo we-fucoidan kwiimpuku ezihluphekayo kwi-Lewis lung adenocarcinoma, kwaye wondliwa i-fucoidan ngedosi ye-10mg / kg kwiimpuku, okukhokelela ekusebenzeni okuphakathi kokuchasana nethumba kunye nesiphumo sokuchasana ne-tumor metastasis. Olunye uphando luye lwafumanisa ukuba izinga lokuvinjelwa kwethumba le-fucoidan kwizilwanyana ezi-5 eziqulethe i-S180 sarcoma yi-30%, kunye ne-sarcoma yezilwanyana ezi-2 zaphela ngokupheleleyo. Kwisitya se-petri esimalunga ne-10,000 yeeseli zomhlaza wekolon eziphathwe nge-algae yendalo ye-polysaccharides efunyenwe kwi-kelp, i-50 yepesenti yeeseli zomhlaza zafa emva kweeyure ze-24, kwaye phantse zonke iiseli zomhlaza zafa emva kweeyure ezingama-72. Hyun et al. yafumanisa ukuba i-polysaccharide ye-algae yamatye inokuthintela ngokubonakalayo ukukhula kweeseli zomhlaza we-colon HCT-15. Emva kokunyangwa kwe-HCT-15 ye-cell line kunye ne-rock algae polysaccharide, iziganeko ze-apoptotic ezifana nokuphulwa kwe-DNA, ukuhlanganiswa kwe-chromosome, kunye nokwanda kweeseli ze-subdiploid kwisigaba se-G1.
6. Iziphumo ze-Antioxidant
Inani elikhulu lovavanyo lwe-in vitro lubonise ukuba i-polysaccharide ye-algae yamatye inomsebenzi omkhulu we-antioxidant, luhlobo lwe-antioxidant yendalo, kwaye inokuthintela ngokufanelekileyo isifo esibangelwa yi-radicals yamahhala. Costa et al. ikhutshwe i-polysaccharides ye-sulfated kwiintlobo ze-11 ze-seaweed, zonke zine-antioxidant umsebenzi, ukukwazi ukwenza i-chelates ye-ferrous kunye nokunciphisa amandla, i-5 eyayinamandla okususa i-hydroxyl radicals, kunye ne-6 eyayinamandla okususa i-peroxy radicals. UMicheline et al. ingxelo yokuba i-polysaccharides evela kwi-algae inokuthintela ukubunjwa kwe-hydroxyl radical kunye ne-superoxide radical.
7. Umsebenzi wamajoni omzimba
I-Fucoidan inemisebenzi emininzi ye-immune, kubandakanywa umsebenzi wokuchasana, impendulo echasayo kunye nemiphumo ye-immunomodulatory. Tissot et al. iqinisekisile ukuba i-polysaccharide ye-fucoite inokuthintela iprotheni ehambelanayo kwi-serum yabantu eqhelekileyo, ngaloo ndlela inqanda ukuchithwa kweeseli zegazi ezibomvu zezimvu ezibangelwa kukusebenza kokuncedisana, kunye nokuthintela ukusebenza kokuncedisa ngokuthintela isinyathelo sokuqala sendlela yokusebenza ye-classical (kubandakanywa icandelo lokuqala lomphelelisi, elesibini kunye nelesine). Yang et al. wafumanisa ukuba i-fucoidan inokuthintela ngokukhethekileyo ukubonakaliswa kwe-inducible nitric oxide synthase kwiiseli ezivuthayo kwaye inomsebenzi ochasayo. Mizuno et al. isebenzise inkqubo yenkcubeko ye-epithelial yamathumbu eCaco-2 kunye ne-macrophage RAW264.7 ukuvavanya isiphumo esichasayo sokudumba kwezinto zokutya, kwaye iziphumo zibonise ukuba i-polysaccharide ye-S. japonicum inokukhuthaza ukuveliswa kwe-tumor necrosis factor.α kwi-RAW264.7, ngaloo ndlela inqanda ukubonakaliswa kwe-mRNA ye-interleukin kwiiseli zeCaco-2.
8. Ukuphucula umgangatho wamadlozi
Ukulawulwa kwe-fucoidan kunokuphucula umgangatho wesidoda kunye nobuninzi ngokuphucula i-metabolites yegazi kunye ne-intestinal microbiota. Abaphandi bafumanisa ukuba emva kokulawulwa nge-polysaccharides yolwandle, amanqanaba okubonakaliswa kwemfuza ehambelana ne-spermatogenesis aye anda kakhulu kwiimvavanyo zeempuku. Ngelo xesha, kwakukho ulungelelwaniso oluhle phakathi kwe-intestinal microbiota kunye ne-metabolites yegazi. Ngokulawula ezi zimbini, i-polysaccharide ye-fucoite iphucule i-metabolites ye-testis, inyuse ukukhuselwa kwe-antioxidant, kunye nokulawula inqanaba lokubonakaliswa kweejene ezihambelanayo kwiiseli zentsholongwane, ngaloo ndlela igalelo kwi-spermatogenesis kunye nokuphucula umgangatho.
Isicelo:
I-Fucoidan isetyenziswa ngokubanzi kwiinkalo ezininzi, ngakumbi kubandakanya le miba ilandelayo:
1. Intsimi yezoNyango: I-Fucoidan isetyenziswe kwezinye iziyobisi, ngakumbi kwezinye izidakamizwa ze-immunomodulatory kunye ne-antioxidant, ukunceda ukuphucula izifo ezingapheliyo kunye nokukhuthaza ukubuyiswa.
2. Ishishini lokutya: I-Fucoidan isoloko isetyenziselwa ukongezwa kokutya ukunyusa ixabiso lesondlo kunye nokusebenza kokutya. Ingasetyenziswa kwizinto ezahlukeneyo zokutya, ezifana ne-ayisikrimu, iziselo, isonka, njl.
3. Izithambiso kunye neemveliso zokunakekelwa kwesikhumba: Ngenxa yeempawu zayo ze-antioxidant kunye ne-moisturizing, i-fucoidan isetyenziswa ngokubanzi kwiimveliso zokunakekelwa kwesikhumba kunye nezithambiso, ezinceda ukuphucula ukuthungwa kwesikhumba kunye nokunciphisa ukubonakala kwemigca emihle kunye nemibimbi.
4. Izixhobo zonyango: I-Fucoidan iphinda isetyenziswe kwezinye izixhobo zonyango kunye nezixhobo zonyango ukukhuthaza ukuphulukiswa kwesilonda kunye nokunciphisa ukusuleleka.
Ngokubanzi, i-fucoidan isetyenziswa ngokubanzi kumayeza, ukutya, izithambiso, kunye nezixhobo zonyango ngenxa yeenzuzo zayo ezininzi kunye nemisebenzi.
Ukupakishwa kunye nokuhanjiswa
