INewgreen eyona iThengisa kakhulu i-S-adenosyl methionine 99% Yongeza i-S-adenosyl methionine Powder eneXabiso eliPhezulu
Ingcaciso yeMveliso
I-S-Adenosyl Methionine (i-SAM okanye i-SAMe) i-compound eveliswa ngokwemvelo emzimbeni, ngokukodwa i-synthesized from adenosine triphosphate (ATP) kunye ne-methionine. I-SAMe idlala indima ebalulekileyo kwiimpendulo ezininzi ze-biochemical, ngakumbi kwiimpendulo ze-methylation.
Iimpawu eziphambili
1. Umnikeli we-Methyl: I-SAMe yi-methyl donor ebalulekileyo kwaye ithatha inxaxheba kwinkqubo ye-methylation ye-DNA, i-RNA kunye neprotheni. Ezi mpendulo ze-methylation zibalulekile kwi-gene expression, ukubonakaliswa kweeseli kunye nokulawulwa kwe-metabolic.
2. Ukwenziwa kweeamolekyu ze-bioactive: I-SAMe ibandakanyeka kwi-synthesis yee-molecule ze-bioactive, kuquka i-neurotransmitters (efana ne-dopamine kunye ne-norepinephrine) kunye ne-phospholipids (njenge-phosphatidylcholine).
3. I-Antioxidant Effect: I-SAMe ineempawu ze-antioxidant ezinokukunceda ukukhusela iiseli kumonakalo obangelwa uxinzelelo lwe-oxidative.
Ukuqukumbela, i-S-adenosylmethionine yi-biomolecule ebalulekileyo enemisebenzi emininzi yezinto eziphilayo kunye nezicelo zeklinikhi ezinokubakho, kodwa kufuneka isetyenziswe ngononophelo kwaye ngokuhambelana neengcebiso zeengcali.
I-COA
Isatifiketi sokuHlalutya
| Izinto | Iinkcukacha | Iziphumo | |
| Imbonakalo | Umgubo omhlophe ukuya kumhlophe | Iyahambelana | |
| Ivumba | I-infrared | Iyahambelana ne-reference spectrum | Iyahambelana |
| HPLC | Ixesha lokugcinwa kwencopho enkulu ihambelana nesampulu yereferensi | Iyahambelana | |
| Isiqulatho samanzi(KF) | ≤ 3.0% | 1.12% | |
| Uthuthu lweSulfate | ≤ 0.5% | Iyahambelana | |
| PH(5% isisombululo samanzi) | 1.0-2.0 | 1.2% | |
| S,S-Isomer(HPLC) | ≥ 75.0% | 82.16% | |
| SAM-e ION(HPLC) | 49.5%-54.7% | 52.0% | |
| I-P-Toluenesulfonic Acid | 21.0%-24.0% | 22.6% | |
| Umxholo weSulfate(SO4)(HPLC) | 23.5%-26.5% | 25.5% | |
| Uvavanyo (S-Adenosyl-L-methionine Disulfate Tosylate) | 95.0%-102% | 99.9% | |
| Izinto eziyeleleneyo(HPLC) | |||
| S-ADENOSYL-L-HOMOCYSTEINE | ≤ 1.0% | 0.1% | |
| ADENINE | ≤ 1.0% | 0.2% | |
| METHYLTHIOADENOSINE | ≤ 1.5% | 0.1% | |
| ADENOSINE | ≤ 1.0% | 0.1% | |
| UBUNGCOLA BONKE | ≤3.5% | 0.8% | |
| Unizi lolwapho kuyiwa khona | > 0.5g/ml | Iyahambelana | |
| Intsimbi enzima | <10ppm | Iyahambelana | |
| Pb | < 3ppm | Iyahambelana | |
| As | <2ppm | Iyahambelana | |
| Cd | <1ppm | Iyahambelana | |
| Hg | <0.1ppm | Iyahambelana | |
| IMicrobiology | |||
| Ukubalwa kwePleti iyonke | ≤ 1000cfu/g | <1000cfu/g | |
| Igwele kunye nokungunda | ≤ 100cfu/g | <100cfu/g | |
| E.Coli. | Ibi | Ibi | |
| Salmonella | Ibi | Ibi | |
| Ukuqukumbela
| Ihambelana ne-USP37 | ||
| Ugcino | Gcina kwi-2-8℃ kwindawo engakhenkcezi, gcina kude nokukhanya okuqinileyo kunye nobushushu | ||
| Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo | ||
Umsebenzi
I-S-Adenosine Methionine (i-SAMe) yinto eyenzeka ngokwemvelo emzimbeni, ngokuyinhloko iqulunqwe yi-adenosine kunye ne-methionine. Idlala indima ebalulekileyo kwiinkqubo ezininzi zebhayoloji. Nantsi eminye yemisebenzi ephambili ye-SAMe:
1. Umnikeli weMethyl:I-SAMe ngumnikeli we-methyl obalulekileyo kwaye ithatha inxaxheba kwiimpendulo ze-methylation emzimbeni. Ezi mpendulo zibalulekile kukuguqulwa kwe-DNA, i-RNA kunye neeprotheni, ezichaphazela ukubonakaliswa kofuzo kunye nokusebenza kweeseli.
2. Khuthaza i-neurotransmitter synthesis:I-SAMe inceda ukudibanisa iintlobo ngeentlobo zee-neurotransmitters kwinkqubo ye-nervous, njenge-serotonin kunye ne-dopamine, ehambelana ngokusondeleyo nommiselo wemo kunye nempilo yengqondo.
3. Iziphumo zokuthomalalisa uxinzelelo:Olunye uphando lubonise ukuba i-SAMe inokuba nefuthe elihle kuxinzelelo njengonyango olongezelelweyo, inceda ekuphuculeni isimo sengqondo kunye nokunciphisa iimpawu zokudakumba.
4. Impilo Yesibindi:I-SAMe idlala indima ebalulekileyo kwisibindi, ithatha inxaxheba kwinkqubo yokutshatyalaliswa kwesibindi kunye ne-fat metabolism, inceda ukukhusela iiseli zesibindi kunye nokukhuthaza impilo yesibindi.
5. Impilo edibeneyo:I-SAMe isetyenziselwa ukukhulula ukuvuvukala kunye neentlungu ezidibeneyo, kwaye inokuphucula umsebenzi odibeneyo ngokukhuthaza ukuhlanganiswa kunye nokulungiswa kwe-cartilage.
6. Impembelelo yeAntioxidant:I-SAMe ineempawu ezithile ze-antioxidant ezinceda ukukhusela iiseli kumonakalo obangelwa luxinzelelo lwe-oxidative.
Ngokubanzi, i-S-adenosylmethionine idlala indima ebalulekileyo kwiinkqubo ezahlukeneyo ze-physiological, ngokukodwa kwimpilo yengqondo, ukusebenza kwesibindi, kunye nempilo edibeneyo. Nangona ukusetyenziswa kwayo njengesongezelelo kuya kuxhaphaka, kungcono ukudibana nogqirha okanye ingcali ngaphambi kokuba uyisebenzise.
Isicelo
I-S-Adenosyl Methionine (SAMe) isetyenziswa ngokubanzi kwiinkalo ezininzi, ingakumbi ezibandakanya le miba ilandelayo:
1. Uxinzelelo kunye nokuphazamiseka kweemvakalelo
I-SAMe iye yaphononongwa njengesongezelelo sokunceda kunyango lokudakumba. Uphando lucebisa ukuba i-SAMe inokuphucula isimo sengqondo ngokunyusa amanqanaba e-neurotransmitters anjenge-dopamine kunye ne-norepinephrine. Olunye ulingo lwezonyango lubonise ukuba i-SAMe inokusebenza njengamayeza esintu okudakumba ekudambiseni iimpawu zokudakumba.
2. Impilo edibeneyo
I-SAMe isetyenziselwa ukunyanga i-osteoarthritis kunye nezinye iimeko ezidibeneyo. Inokunceda izigulane ngokunciphisa intlungu edibeneyo kunye nokuphucula umsebenzi. Olunye uphononongo lucebisa ukuba i-SAMe iyasebenza ngokufanayo njengamachiza achasene nokudumba (nonsteroidal anti-inflammatory drugs) (NSAIDs) ekudambiseni ukudumba kwamalungu kunye neentlungu, kodwa zineziphumo ebezingalindelekanga ezimbalwa.
3. Impilo yesibindi
I-SAMe ikwabonise amandla kunyango lwezifo zesibindi. Isetyenziselwa ukunyanga iimeko ezifana ne-steatosis yesibindi, i-hepatitis, kunye ne-cirrhosis. I-SAMe inokusebenza ngokukhuthaza ukuvuselelwa kweeseli zesibindi kunye nokuphucula ukusebenza kwesibindi.
4. Impilo ye-nervous system
I-SAMe ikwafumene ingqwalasela kuphando lwezifo ze-neurodeergenerative ezifana ne-Alzheimer's kunye ne-Parkinson's. Inokuxhasa impilo ye-nervous system ngokuphucula i-synthesis ye-neurotransmitters kunye nokunciphisa uxinzelelo lwe-oxidative.
5. IMpilo ye-Cardiovascular
Olunye uphando lucebisa ukuba i-SAMe inokuxhamla kwimpilo yentliziyo, ngokuthoba amanqanaba e-homocysteine (i-homocysteine ephezulu inxulunyaniswa nobungozi besifo sentliziyo).
6. Ezinye izicelo
I-SAMe ikwafundelwa eminye imiba yezempilo, efana ne-fibromyalgia, isifo esingapheliyo sokukhathala, kunye neentlobo ezithile zomhlaza. Nangona uphando kwezi zicelo lusaqhubeka, iziphumo zokuqala zibonisa isithembiso esithile.
Amanqaku
Ngaphambi kokusebenzisa i-SAMe njengesongezelelo, kuyacetyiswa ukuba udibane nogqirha, ngakumbi kubantu abaneengxaki ezithile zempilo okanye abathatha amanye amayeza. I-SAMe inokunxibelelana namayeza athile, afana ne-antidepressants, ngoko ke isikhokelo sobuchule sibalulekile.
Ekugqibeleni, i-S-adenosylmethionine inezicelo ezinokubakho kwiindawo ezininzi zempilo, kodwa uphando olongezelelweyo luyafuneka ukuze kuqinisekiswe ngakumbi ukusebenza kwayo kunye nokhuseleko.
Ukupakishwa kunye nokuhanjiswa
