Donepezil HCl Newgreen Supply High Quality APIs 99% Donepezil HCl Powder
Ingcaciso yeMveliso
I-Donepezil HCl lichiza elisetyenziselwa ukunyanga isifo se-Alzheimer kunye nezinye iintlobo ze-dementia ephakathi ukuya kwephakathi. Kukwiklasi yeziyobisi ezibizwa ngokuba yi-acetylcholinesterase inhibitors, ephucula umsebenzi wokuqonda ngokunyusa izinga le-acetylcholine engqondweni.
Oomatshini abaphambili
Ukuthintela i-acetylcholinesterase:
I-Donepezil inqanda umsebenzi we-acetylcholinesterase, ukunciphisa ukuthotywa kwe-acetylcholine, ngaloo ndlela iphucula ukuhanjiswa kwesignali phakathi kwe-neurons.
Ukuphucula ukusebenza kwengqondo:
Ngokwandisa i-acetylcholine concentrations, i-Donepezil inokuphucula imemori, ukucinga nokufunda, inceda ukunciphisa iimpawu kwizigulane ezine-Alzheimer's disease.
Iimpawu
I-Donepezil HCl isetyenziswa ikakhulu kwezi meko zilandelayo:
Isifo sika-Alzheimer:
Kunyango lwesifo se-Alzheimer esithambileyo ukuya kwimodareyitha, ukunceda ukuphucula umsebenzi wokuqonda kunye nobuchule bokuphila bemihla ngemihla.
Ezinye iintlobo zedementia:
Kwezinye iimeko, i-Donepezil ingasetyenziselwa ukulawula iimpawu zezinye iintlobo ze-dementia.
I-COA
Izinto | Iinkcukacha | Iziphumo |
Imbonakalo | Umgubo omhlophe | Iyahambelana |
Umyalelo | Uphawu | Iyahambelana |
Isivavanyi | ≥99.0% | 99.8% |
Wangcamla | Uphawu | Iyahambelana |
Ilahleko ekomisweni | 4-7(%) | 4.12% |
IAsh iyonke | 8% Ubuninzi | 4.85% |
Intsimbi enzima | ≤10(ppm) | Iyahambelana |
Arsenic(As) | 0.5ppm Ubuninzi | Iyahambelana |
Khokela(Pb) | 1ppm Max | Iyahambelana |
IMercury(Hg) | 0.1ppm Max | Iyahambelana |
Ubalo lwePleti lulonke | 10000cfu/g Ubuninzi. | 100cfu/g |
Igwele kunye noMngundo | 100cfu/g Ubuninzi. | >20cfu/g |
Salmonella | Ibi | Iyahambelana |
E.Coli. | Ibi | Iyahambelana |
Staphylococcus | Ibi | Iyahambelana |
Ukuqukumbela | Ufanelekile | |
Ugcino | Gcina kwindawo evaliweyo kunye neqondo lokushisa eliphantsi rhoqo kwaye akukho kukhanya kwelanga ngqo. | |
Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo |
Imiphumela
I-Donepezil HCl inokubangela iziphumo ebezingalindelekanga, kubandakanya:
Ukusabela kwamathumbu: njengesicaphucaphu, ukugabha, urhudo okanye ukungakucaceli ukutya.
Ukuphuthelwa: Ezinye izigulana zinokuphuthelwa okanye zinengxaki yokulala.
Izihlunu ezibuhlungu: Izihlunu okanye ukuxhuzula kunokwenzeka.
Iziphumo zentliziyo: njengesantya sentliziyo esicothayo (bradycardia) okanye uxinzelelo lwegazi oluphantsi.
Amanqaku
Ukubeka iliso: Izigulane kufuneka zibekwe esweni rhoqo ngomsebenzi wokuqonda kunye nemiphumo emibi ngelixa usebenzisa i-Donepezil.
Umsebenzi weHepatic: Sebenzisa ngokuqaphela kwizigulane ezine-hepatic impairment; ukulungiswa kwethamo kunokufuneka.
Ukusebenzisana kweziyobisi: I-Donepezil inokunxibelelana namanye amachiza. Kufuneka uxelele ugqirha wakho ngazo zonke iziyobisi ozithathayo ngaphambi kokuba uyisebenzise.