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Ingcaciso yeMveliso
I-Cyclosporin yi-immunosuppressant esetyenziswa ngokuyinhloko ukukhusela ukulahlwa kwe-organ transplant kunye nokunyanga izifo ezithile ezizimele. Ikhutshwe kwifungi yomhlaba kwaye inesiphumo sokuthintela ngokukhethiweyo ukusebenza kwe-T cell.
Oomatshini abaphambili
Inhibit T cell ukusebenza:
I-Cyclosporin inqanda umsebenzi we-phosphatase exhomekeke kwi-calcineurin (calcineurin) ngokuzibophelela kwiprotheni ye-cyclophilin-binding kwiiseli, ngaloo ndlela ikhusela ukusebenza kunye nokwanda kweeseli ze-T kunye nokunciphisa ukuphendula komzimba.
Iimpawu
I-Cyclosporin isetyenziswa kakhulu kwezi meko zilandelayo:
I-Organ Transplant: Isetyenziselwa ukunqanda ukugatywa kwamalungu afana nezintso, isibindi, kunye neentliziyo emva kokutshintshwa, ngokuqhelekileyo kudibaniswa namanye ama-immunosuppressants.
Izifo ezizimelayo: Ingasetyenziselwa ukunyanga izifo ezizimelayo ezifana ne-rheumatoid arthritis, i-psoriasis, i-Sjögren's syndrome, njl.
Ezinye izibonakaliso: Kwezinye iimeko, i-Cyclosporin ikwasetyenziselwa ukunyanga ukuguquguquka okukhulu kunye neemeko ezithile zolusu.
I-COA
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo omhlophe | Iyahambelana |
| Umyalelo | Uphawu | Iyahambelana |
| Isivavanyi | ≥99.0% | 99.8% |
| Wangcamla | Uphawu | Iyahambelana |
| Ilahleko ekomisweni | 4-7(%) | 4.12% |
| IAsh iyonke | 8% Ubuninzi | 4.85% |
| Intsimbi enzima | ≤10(ppm) | Iyahambelana |
| Arsenic(As) | 0.5ppm Ubuninzi | Iyahambelana |
| Khokela(Pb) | 1ppm Max | Iyahambelana |
| IMercury(Hg) | 0.1ppm Max | Iyahambelana |
| Ukubalwa kwePleti iyonke | 10000cfu/g Ubuninzi. | 100cfu/g |
| Igwele kunye noMngundo | 100cfu/g Ubuninzi. | ＞20cfu/g |
| Salmonella | Ibi | Iyahambelana |
| E.Coli. | Ibi | Iyahambelana |
| Staphylococcus | Ibi | Iyahambelana |
| Ukuqukumbela | Ufanelekile | |
| Ugcino | Gcina kwindawo evaliweyo kunye neqondo lokushisa eliphantsi rhoqo kwaye akukho kukhanya kwelanga ngqo. | |
| Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo | |
Umsebenzi
Imiphumela
I-Cyclosporin inokubangela iziphumo ebezingalindelekanga, kubandakanya:
Nephrotoxicity:Inokubangela ukukhubazeka kwezintso kwaye ifuna ukujongwa rhoqo komsebenzi wezintso.
Igazi elonyukayo:Ukusetyenziswa kweCyclosporin kunokubangela ukonyuka koxinzelelo lwegazi.
Umngcipheko wosulelo:Ngenxa ye-immunosuppression, izigulana zinokuchaphazeleka ngakumbi kusulelo.
Ezinye iziphumo ebezingalindelekanga:njengentloko ebuhlungu, ukungahambi kakuhle kwesisu, i-gingival hyperplasia, njl.
Amanqaku
Ukubeka iliso:Xa usebenzisa i-Cyclosporin, umsebenzi wezintso, uxinzelelo lwegazi kunye nokugxilwa kweziyobisi zegazi kufuneka zibekwe esweni rhoqo.
Ukusebenzisana kweziyobisi:I-Cyclosporin inokunxibelelana namanye amachiza. Kufuneka uxelele ugqirha wakho ngazo zonke iziyobisi ozithathayo ngaphambi kokuba uyisebenzise.
Ukukhulelwa kunye nokuncancisa:I-Cyclosporin kufuneka isetyenziswe ngokuqaphela ngexesha lokukhulelwa kunye nokuncelisa kunye nokubonisana nodokotela kuyadingeka.
Ukupakishwa kunye nokuhanjiswa
Umsebenzi
Umsebenzi kaNerol
I-Nerol i-alcohol ye-monoterpene yendalo kunye ne-chemical formula C10H18O. Ifumaneka kakhulu kwiioli eziyimfuneko zezityalo ezahlukeneyo, ezifana nerose, i-lemongrass kunye ne-mint. UNerol unemisebenzi emininzi kunye nezicelo, ingakumbi ezibandakanya le miba ilandelayo:
1. Ivumba nevumba:I-Nerol inevumba elitsha, intyatyambo kwaye ihlala isetyenziswa kwiziqholo kunye neziqholo njengesithako sevumba ukonyusa umtsalane wemveliso. Inokongeza amanqaku athambileyo eentyatyambo kwiziqholo.
2. Izithambiso: Kushishino lwezithambiso, i-Nerol isetyenziswa njengesithako sevumba kwaye iqhele ukufunyanwa kwiimveliso ezinjengeemveliso zokhathalelo lwesikhumba, ishampoos kunye nejeli zeshawa ukunyusa amava omsebenzisi.
3. Isongezo sokutya:I-Nerol ingasetyenziswa njengesiqholo sokutya kwaye yongezwe kwiziselo, iilekese kunye nokunye ukutya ukunika incasa yeentyatyambo.
4. Umsebenzi webhayoloji:Uphononongo lubonise ukuba i-Nerol inokuba ne-antibacterial, i-antioxidant kunye ne-anti-inflammatory imisebenzi ye-biological, eyenza ibe nomdla ekuphuhlisweni kweziyobisi kunye nezongezo zezempilo.
5. Ukugxotha izinambuzane:I-Nerol ifunyenwe ineziphumo zokugxotha izinambuzane kwaye inokusetyenziswa njengento yendalo yokugxotha izinambuzane ukunceda ukukhusela izinambuzane.
6. Aromatherapy:Kwi-aromatherapy, i-Nerol isetyenziselwa ukuphumla kunye nokukhululeka koxinzelelo ngenxa yevumba layo elipholileyo, inceda ukuphucula isimo sengqondo kunye nemeko yengqondo.
Ukuqukumbela, uNerol udlala indima ebalulekileyo kwiinkalo ezininzi ezifana neziqholo, izithambiso, ukutya, uphando lwamayeza kunye ne-aromatherapy ngenxa yevumba layo elahlukileyo kunye nemisebenzi emininzi yebhayoloji.
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