I-Baclofen Powder yeNdalo ecocekileyo yoMgangatho weBaclofen Powder
Ingcaciso yeMveliso
I-Baclofen, eyaziwa ngokuba yi-Becomphin, i-Becomphin, kunye ne-Li Luxing, igama leziyobisi yi-chirosol, i-Liolexin, i-chloraminobutyric acid, iphuma kwi-gamma-aminobutyric acid, ichiza le-spasmolytic, ngenxa yesenzo senkqubo ye-nervous central kunye ne-spinal cord skeletal. ukuphumla kwezihlunu, ukuthomalalisa. Inokuthintela ukukhutshwa kwe-amino acids enomdla njenge-glutamic acid kunye ne-aspartate ngokuvuselela i-receptor, kwaye ngaloo ndlela inqanda ukuhanjiswa kwe-synaptic enye kunye ne-multi-synaptic reflex kwingqondo kunye nentambo yomgogodla wenkqubo ye-nervous central, ukuze udlale indima spasmotic. Ngokweklinikhi, isetyenziswe njengolungiselelo lobuhlanga kunyango lwe-muscle ye-Chemicalbook spasticity ukususela phakathi kwe-1960s. Uphononongo lwakutsha nje luye lwafumanisa ukuba le mveliso inokunciphisa kakhulu i-reflux ye-gastroesophageal kwaye iphucule iimpawu zayo, ikhulule ngokufanelekileyo iimpawu ze-dystonia ebantwaneni, kwaye iphathe ukungasebenzi kakuhle kokuchama emva kokulimala okuphakathi kwe-spinal refractory. Ukongeza, ukusetyenziswa kweklinikhi yonyango lwenaliti ye-intrathecal kunokuphucula ngakumbi ukusebenza kweklinikhi kunye nokulungelelanisa umthamo weziyobisi nangaliphi na ixesha ukuzinzisa isiphumo sonyango. Kwiminyaka eyi-10 edlulileyo, ukusetyenziswa kweklinikhi ye-baclofen ye-muscle epholileyo yenze inkqubela phambili enkulu, ngakumbi kunyango lokuvuselela i-nerve yokunciphisa ithoni yemisipha kunye nokunciphisa intlungu.
I-COA
Izinto | Iinkcukacha | Iziphumo |
Imbonakalo | Umgubo omhlophe | Iyahambelana |
Umyalelo | Uphawu | Iyahambelana |
Isivavanyi | ≥99.0% | 99.5% |
Wangcamla | Uphawu | Iyahambelana |
Ilahleko ekomisweni | 4-7(%) | 4.12% |
IAsh iyonke | 8% Ubuninzi | 4.85% |
Intsimbi enzima | ≤10(ppm) | Iyahambelana |
Arsenic(As) | 0.5ppm Ubuninzi | Iyahambelana |
Khokela(Pb) | 1ppm Max | Iyahambelana |
IMercury(Hg) | 0.1ppm Max | Iyahambelana |
Ukubalwa kwePleti iyonke | 10000cfu/g Ubuninzi. | 100cfu/g |
Igwele kunye noMngundo | 100cfu/g Ubuninzi. | >20cfu/g |
Salmonella | Ibi | Iyahambelana |
E.Coli. | Ibi | Iyahambelana |
Staphylococcus | Ibi | Iyahambelana |
Ukuqukumbela | CoNONE | |
Ugcino | Gcina kwindawo evaliweyo kunye neqondo lokushisa eliphantsi rhoqo kwaye akukho kukhanya kwelanga ngqo. | |
Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo |
Umsebenzi
Uxinzelelo yi-skeletal muscle relaxant kunye ne-spasmolytic agent esebenza kumqolo. Kwi-skeletal femoral spasm kwi-multiple sclerosis; Ukusuleleka kwintambo yomgogodla, i-spasms yemisipha ewohlokayo; I-spasms ye-muscle eyothukileyo kunye neyongezelelweyo yentambo yomgogodla.
Isicelo
Okwangoku yeyona nto isebenzayo yokuphumza izihlunu kunye neziphumo ebezingalindelekanga ezincinci.