Ticagrelor Newgreen Supply APIs 99% Ticagrelor Powder
Product Description
Ticagrelor is an antiplatelet drug, a P2Y12 receptor antagonist, used primarily to prevent cardiovascular events, especially in patients with acute coronary syndrome (ACS). It reduces the risk of thrombosis by inhibiting platelet aggregation.
Main Mechanics
Inhibit platelet aggregation:
Ticagrelor reversibly binds to the P2Y12 receptor on the platelet surface, inhibiting platelet activation and aggregation caused by adenosine diphosphate (ADP), thereby reducing thrombus formation.
Indications
Ticagrelor is mainly used in the following situations:
Acute Coronary Syndrome: Including patients with unstable angina and myocardial infarction, usually used in combination with aspirin to reduce the risk of cardiovascular events.
Secondary prevention of cardiovascular events: For patients who have already had a cardiovascular event to prevent another one.
COA
Items | Specifications | Results |
Appearance | White powder | Complies |
Order | Characteristic | Complies |
Assay | ≥99.0% | 99.8% |
Tasted | Characteristic | Complies |
Loss on Drying | 4-7(%) | 4.12% |
Total Ash | 8% Max | 4.85% |
Heavy Metal | ≤10(ppm) | Complies |
Arsenic(As) | 0.5ppm Max | Complies |
Lead(Pb) | 1ppm Max | Complies |
Mercury(Hg) | 0.1ppm Max | Complies |
Total Plate Count | 10000cfu/g Max. | 100cfu/g |
Yeast & Mould | 100cfu/g Max. | >20cfu/g |
Salmonella | Negative | Complies |
E.Coli. | Negative | Complies |
Staphylococcus | Negative | Complies |
Conclusion | Qualified | |
Storage | Store in a well-closed place with constant low temperature and no direct sun light. | |
Shelf life | 2 years when properly stored |
Side Effect
Ticagrelor is generally well tolerated, but some side effects may occur, including:
Bleeding: The most common side effect, which may result in mild or severe bleeding events.
Difficulty breathing: Some patients may experience difficulty breathing or coughing.
Gastrointestinal reactions: such as nausea, abdominal pain or indigestion.
Notes
Bleeding Risk: The risk of bleeding should be monitored regularly when using Ticagrelor, especially when used concomitantly with other anticoagulant drugs.
Hepatic Function: Use with caution in patients with hepatic impairment; dose adjustment may be necessary.
Drug Interactions: Ticagrelor may interact with other drugs. You should tell your doctor about all the drugs you are taking before using it.