TanshinoneⅡA 99% Manufacturer Newgreen TanshinoneⅡA 99% Powder Supplement
Product Description
Tanshinone, also known as total tanshinone, is a fat-soluble phenanthrenequinone compound with antibacterial effect extracted from the traditional Chinese medicine Salvia miltiorrhiza (Lamiaceae plant Salvia miltiorrhiza root), from which tanshinone I, tanshinone IIA, tanshinone IIB, cryptotanshinone, and isocryptozolin are separated There are more than 10 tanshinone monomers including tanshinone, among which 5 monomers: cryptotanshinone, dihydrotanshinone II, hydroxytanshinone, methyl tanshinone, and tanshinone IIB, have antibacterial effects, as well as anti-inflammatory and cooling effects. Tanshinone IIA sodium sulfonate, the sulfonated product of tanshinone IIA, is soluble in water. Clinical trials have proven that it has significant effects in treating angina pectoris with few side effects. It is a new drug for the treatment of coronary heart disease. Tanshinone has many functions such as antibacterial, anti-inflammatory, promoting blood circulation and promoting wound healing. There are no obvious side effects after long-term use.
Tanshinone IIA is orange-red needle-like crystal (EtOAc), mp 209~210 ℃. Easily soluble in ethanol, acetone, ether, benzene and other organic solvents, slightly soluble in water.
COA
Items | Specifications | Results | |
Appearance | Brown Powder | Brown Powder | |
Assay |
|
Pass | |
Odor | None | None | |
Loose Density(g/ml) | ≥0.2 | 0.26 | |
Loss on Drying | ≤8.0% | 4.51% | |
Residue on Ignition | ≤2.0% | 0.32% | |
PH | 5.0-7.5 | 6.3 | |
Average molecular weight | <1000 | 890 | |
Heavy Metals(Pb) | ≤1PPM | Pass | |
As | ≤0.5PPM | Pass | |
Hg | ≤1PPM | Pass | |
Bacterial Count | ≤1000cfu/g | Pass | |
Colon Bacillus | ≤30MPN/100g | Pass | |
Yeast & Mold | ≤50cfu/g | Pass | |
Pathogenic Bacteria | Negative | Negative | |
Conclusion | Conform with specification | ||
Shelf life | 2 years when properly stored |
Function
1. Improve heart disease: Salvia miltiorrhiza extract has a certain protective effect on heart and blood vessels, can resist arrhythmia, resist arteriosclerosis, improve microcirculation, and is conducive to the auxiliary treatment of heart disease;
2. Inhibit platelet aggregation: Salvia miltiorrhiza extract can inhibit the activity of coronary artery platelets, and then inhibit platelet aggregation activity;
3. Reduce hyperlipidemia: Salvia miltiorrhiza extract can inhibit the activity of the fibrinolytic system to a certain extent, and play a role in reducing hyperlipidemia and stabilizing atherosclerosis.
Application
1. Antibacterial effect In vitro experiments show that tanshinone has a stronger antibacterial effect on Staphylococcus aureus than berberine. It also has an inhibitory effect on Mycobacterium tuberculosis H37RV strain (the lowest inhibitory concentration can reach less than 1.5 mg/mL) and two types of trichophyton.
2. Anti-inflammatory effect: Tanshinone administered by gavage to rats has obvious anti-inflammatory effect. In the first stage of inflammation model, it has a significant inhibitory effect on the increase in capillary permeability caused by histamine; it has an inhibitory effect on acute joint swelling caused by egg white, carrageenan and dextran; it has an inhibitory effect on exudative formaldehyde peritonitis. effect.
3.Anticoagulant effect Tanshinone has anticoagulant effect. The effect is stronger than that of protoethyl aldehyde.