Terbinafine Hydrochloride High Purity API Material CAS 78628-80-5
Tlhaloso ea Sehlahisoa
Terbinafine Hydrochlorideke moriana oa antifungal o sebelisoang ho phekola mafu a fapaneng. Hangata e etsoa ka mokhoa oa matlapa kapa litlolo. terbinafine hydrochloride ke moriana o sebetsang hantle oa antifungal o sebelisoang ho phekola mafu a fapaneng a fungal. Hore na e sebetsana le tšoaetso ea leoto kapa fungal manala, moriana ona o sebetsa ka ho sitisa tlhahiso ea ergosterol mme o fana ka likhetho tsa kopo ea lihlooho le tsa molomo bakeng sa boiketlo le katleho.
COA
| LINTLHA | TS'ELISO | SEphetho TEKO |
| Tlhahlobo | 99% | E lumellana |
| Mmala | Phofo e tšoeu | E lumellana |
| Monko o monate | Ha ho monko o khethehileng | E lumellana |
| Boholo ba likaroloana | 100% e feta 80mesh | E lumellana |
| Tahlehelo ka ho omisa | ≤5.0% | 2.35% |
| Masala | ≤1.0% | E lumellana |
| Tšepe e boima | ≤10.0ppm | 7ppm |
| As | ≤2.0ppm | E lumellana |
| Pb | ≤2.0ppm | E lumellana |
| Masalla a chefo e bolaeang likokoanyana | E mpe | E mpe |
| Kakaretso ea palo ea lipoleiti | ≤100cfu/g | E lumellana |
| Yeast & Mold | ≤100cfu/g | E lumellana |
| E.Coli | E mpe | E mpe |
| Salmonella | E mpe | E mpe |
| Qetello | Lumellana le Specification | |
| Polokelo | E bolokiloe sebakeng se Phodileng le se omileng, Qoba Leseli le Matla le Mocheso | |
| Shelf bophelo | Lilemo tse 2 ha li bolokiloe hantle | |
Mosebetsi
1.Terbinafine hydrochloride e entsoeng ka allyla antifungal. E na le lipophilic haholo ka tlhaho 'me e atisa ho bokellana letlalong, manala le lisele tse mafura.
2.Terbinafine·HCl setho sa allyl class of antifungals, e fumanoe e le inhibitor e itseng ea ergosterol synthesis ka squalene epoxidase inhibition. Squalene epoxidase ke enzyme e hlahisoang ke li-fungus tsa dermatophyte ho senya Squalene, e sitisang mosebetsi oa lera la sele le sebopeho sa lebota.
3.Terbinafine hydrochloride e na le phello ea fungicidal ho li-fungus tsa letlalo le phello ea inhibitory ho Candida albicans. E loketse bakeng sa mafu a letlalo le manala a bakoang ke li-fungus tse ka holimo, joalo ka seboko, seboko sa 'mele, seboko sa femur, seboko sa maoto, seboko sa manala le ts'oaetso ea Candida albicans ea letlalo e bakoang ke Trichophyton rubrum, Microsporum canis. le Flocculus epidermidis.
Kopo
Terbinafine hydrochloride ke phofo e tšoeu e hloekileng ea kristale e qhibilihang ka bolokolohi ho methan le dichlorome, e qhibilihang ka ethanol, 'me e qhibiliha hanyenyane metsing. Joalo ka li-allylamine tse ling, terbinafine e thibela ergosterol synthesis ka ho thibela squalene epoxidase,
enzyme eo e leng karolo ea fungal cell membrane synthesis pathway. Hobane terbinafine e thibela phetoho ea squalene ho lanosterol, ergosterol ha e khone ho etsoa. Sena se nahanoa hore se fetola ho kenella ha lera la sele, ho baka fungal cell lysis.
1. Terbinafine Hcl e sebetsa haholo-holo ho sehlopha sa dermatophyte sa li-fungus.
2. E le 1% ea tranelate kapa phofo, e sebelisoa ka holimo bakeng sa mafu a ka holimo a letlalo a kang jock itch (tinea cruris),
leoto la moatlelete (tinea pedis), le mefuta e meng ea liboko (tinea corporis). Setlolo sa Terbinafine se sebetsa hoo e ka bang halofo ea nako e hlokahalang
ka lithethefatsi tse ling tsa antifungal.
3. Lipilisi tsa molomo tsa 250mg hangata li laeloa bakeng sa phekolo ea onychomycosis, tšoaetso ea fungal ea lipekere, hangata ke dermatophyte.
kapa mefuta ea Candida. Ts'oaetso ea lipekere tsa fungal e fumaneha botebong ba manala ka har'a cuticle eo ho eona ho sebelisoang kalafo ka holimo
ha di kgone ho phunyeletsa ka bongata bo lekaneng. Matlapa a ka 'na, ka seoelo, a bakang hepatotoxicity, kahoo bakuli ba lemosoa ka sena le
e ka beoa leihlo ka liteko tsa tšebetso ea sebete. Mekhoa e meng ea tsamaiso ea molomo e ithutoe.
4. Terbinafine e ka 'na ea susumetsa kapa ea mpefatsa subacute cutaneous lupus erythematosus. Batho ba nang le lupus erythematosus ba lokela ho
ba buisane pele le ngaka ea bona ka likotsi tse ka bang teng pele ba qala kalafo.
Lihlahisoa tse Amanang
Fektheri ea Newgreen e boetse e fana ka li-amino acid ka tsela e latelang:
Sephutheloana le thomello
