Lilemong tsa morao tjena, ntho e bitsoangNicotinamide Riboside(NR) e hohetse tlhokomelo e atileng sechabeng sa mahlale le lefapheng la bophelo bo botle. NR ke selelekela sa vithamine B3 'me e nkoa e na le matla a khahlanong le botsofali le tlhokomelo ea bophelo bo botle,' me e fetoha sebaka se chesang sa lipatlisiso le nts'etsopele.
NRe fumanoe e eketsa maemo a intracellular a NAD +, coenzyme ea bohlokoa e amehang ho laola metabolism ea cellular le tlhahiso ea matla. Ha lilemo li ntse li eketseha, maemo a NAD+ 'meleng oa motho a fokotseha butle-butle, 'me tlatsetso ea NR e ka thusa ho boloka maemo a phahameng a NAD +, a lebelletsoeng ho liehisa ts'ebetso ea botsofali le ho ntlafatsa ts'ebetso ea lisele.
Ntle le matla a eona a ho thibela botsofali,NRe fumanoe e na le litlamorao tse ntle ho bophelo bo botle ba pelo le methapo, bophelo bo botle ba metabolic, le ts'ireletso ea methapo. Lipatlisiso li bonts'a hore NR e ka ntlafatsa ts'ebetso ea methapo ea mali, maemo a tlase a k'holeseterole, a fokotsa likarabo tsa ho ruruha, 'me a na le melemo e ka bang teng ho thibela lefu la pelo. Ho feta moo, NR e boetse e lumeloa hore e thusa ho laola maemo a tsoekere ea mali, ho ntlafatsa kutloisiso ea insulin, le ho bapala karolo ea ho thibela lefu la tsoekere le botenya. Mabapi le ts'ireletso ea methapo, NR e fumanoe e ntlafatsa tlhahiso ea matla ea lisele tsa boko 'me e lebelletsoe ho bapala karolo e ntle ho thibela mafu a neurodegenerative.
Ha lipatlisiso ka NR li ntse li tsoela pele ho teba, lik'hamphani tse ngata tsa lihlahisoa tsa bophelo bo botle li qala ho eketsa NR e le motsoako o ka sehloohong oa lihlahisoa tsa bophelo bo botle ho finyella litlhoko tsa batho bakeng sa ho thibela botsofali le tlhokomelo ea bophelo bo botle. Ka nako e ts'oanang, liteko tse ling tsa bongaka le tsona li ntse li tsoela pele ho netefatsa katleho le polokeho ea NR mafapheng a fapaneng a bophelo bo botle.
Leha ho le joaloNRe na le bokhoni bo boholo, ho hlokahala lipatlisiso tse ngata ho netefatsa liphello tsa eona tsa nako e telele le polokeho. Ho feta moo, batho ba boetse ba hloka ho khetha lihlahisoa tsa NR ka hloko ho netefatsa hore mehloli ea tsona le boleng ba tsona lia tšepahala. Ha lipatlisiso le nts'etsopele ea NR e ntse e tsoela pele ho teba, ke lumela hore e tla tlisa katleho e ncha le tšepo bophelong ba batho.
Nako ea poso: Aug-29-2024
