Epimedium (Horny poat theat) exarice- icariin e ba ts'epo e ncha

Setsi sa Grino-Tim ke e 'ngoe ea baemeli ba tloaelehileng ba lithako ka ho fetisisa, ka tumor refdurencerence and metastasis ho ba le lintlha tse kholo tsa moferefere. Ka 2023, linyeoe tse hakanyetsoang tse 168,5,560 tsa kankere ea mororako e tla fumanoa United States, e nang le lefu la 32 590; Hoo e ka bang 50% ea linyeoe tsena e le carcinomal ea urothel. Le hoja ho fumaneha ha likhetho tse ncha tsa kalafo, joalo ka chemotherapy e thehiloeng platinoum le pd1 antinomatherapy, batho ba fetang halofo ba sa arabele liphekolo tsena. Ka hona, ho na le tlhoko e potlakileng ea ho hlahloba li-agents tse ncha tsa kalafo ho ntlafatsa bokuli bakuli ba thepa ea li-carcinoma.

Icariin. Hang hoba needwed, ICA e ne e le Metabobelized ho ICARTIN (ICT), e leng seo e fanang ka litlamorao. ICA e na le mesebetsi ea likokoana-hloko, ho kenyelletsa ho laola lefu la ho ikamahanya le maemo, ho ba le thepa ea Antioxidant, le ho thibela ho hatela pele ho tmor. Ka 2022, li-capsules tsa icarin le Icarin tse ka sehloohong li amoheloa ke li-carchinomation tsa China tsa China (Nmpacemalaul carcinoma e ratehang. Ntle le moo, e bontšitse ts'ebetso ea bohlokoa ea ho phekola ho pholoha bakuli ka kakaretso ho pholoho ea bakuli ka kakaretso ea bakuli ba hirileng hipcinoma. Ict ha e bolae ka kotloloho ka ho toba ka kotloloho ka ho kopa tšoarelo le ho jala Leha ho le joalo, mochini o ikhethang oo u o busang tme, haholo-holo carcinoliame, ha a utloisisoe ka botlalo.

Haufinyane, bafuputsi ba tsoang Lefapheng la Urology, RUASAN PUSELETSO EA PUSELETSO EA MOTSOALLE OA MOTSOALLE OA MOTSOALLE OA HAUFORD LE TLHALOSO EA PUARROPITicariinMotsoako o fokotsehileng haholo o hasanya le ho tsoela pele ho phatloha ha neutrophil le net synthesions, ho bonts'a leqheka le lecha la ho urooal.

Bosiu le metastasis ke lisosa tsa mantlha tsa lefu ho la carcinolial carcinoma. Ka har'a likokoana-hloko tse hlatsoang hlama Likokoana-hloko tsa ho ruruha, tse amanang le mabanta a Nuterophlils le neutrophil, li khothalletsa Mastasis. Leha ho le joalo, hajoale ha ho na litlhare tse thibelang neutroic le matlooa.

Thutong ena, bafuputsi ba ile ba bontša lekhetlo la pele lekhetlo la pele seoicariin, tšoaro ea pele ea koloi e tsoetseng pele le e nang le moea o matla oa hepa, e ka fokotsa matlooa a bakoang ke ho emisa ho ipolaea le ho thibela ho kenella ha pelo. Ka mantsoe a mangata, ict e tlama le ho thibela polelo ea Padi2 ka ntle ho neuupphils, ka ho etsa joalo ho thibela pele ho patiolicing ea liphoofolo tsa parati2 tse ngotsoeng ka tsela. Ntle le moo, ict e thibela moloko oa mangoane, o thibela tsela ea matsoho a mapk, 'me e hatella mouoanesi ea thōko ea koetwas.

Ka nako e ts'oanang, ict e thibela li-timor papiso ea li-tempi2 tse ngotsoeng ka har'a eona, ka ho etsa joalo ho thibela sengoloa sa Lifate tsa Li-Neutrophil tse kang GM-CSF le IL-6. Ka lehlakoreng le leng, ho chesa lentsoe la Il-6 ho etsa feela loop ea tlhahiso ea jak2 / Stat3 / il-6 axis. Ka ho ithuta ka ho khutlisa mehlala ea lefutso, bafuputsi ba ile ba fumana tokoloho lipakeng tsa neutrohils, Nets, ho ba le ho ba le botsitso ba Uca. ICT e kopantsoeng le libilione tsa tlhahlobo ea tlhahlobo e ka ba le phello ea syonergin.

Ka kakaretso, thuto ena e fumane seoicariinMotsoako o fokotsehileng haholo o hasanya le ho tsoela pele ho phatloha ha neurophili Ntle le moo, ict e kopantsoe le anti-pd1 anti-Pd1 a na le phello e lumellanang, a fana ka tlhahiso ea leano la kalafo bakeng sa bakuli ba nang le carcinomal carcinoma