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Tlhaloso ea Sehlahisoa
Famotidine ke mohanyetsi oa H2 receptor, haholo-holo e sebelisetsoang ho phekola mafu a amanang le asiti ea gastric. E thibela li-receptor tsa histamine H2 liseleng tsa parietal tsa gastric, e fokotsa secretion ea asiti ea ka mpeng, 'me kahoo e imolla matšoao a bakoang ke asiti e feteletseng ea gastric. Lintlha tse latelang ke kenyelletso e qaqileng ea Famotidine:
Likarolo tse ka Sehloohong le Mesebetsi
1.Mokhoa: Famotidine e thibela tlhahiso ea asiti ea gastric mme e fokotsa acidity ka mpeng ka ho khetha ho hanyetsa li-receptor tsa H2 liseleng tsa parietal tsa gastric.
2. Lipontšo:
- Lefu la Reflux la Gastroesophageal (GERD): E sebelisoa ho imolla matšoao a bakoang ke acid reflux, joalo ka ho otloa ke pelo le ho khutla ha acid.
- Peptic ulcer: e sebelisoa ho phekola seso sa ka mpeng le seso sa duodenal le ho khothaletsa pholiso ea seso.
- Thibelo ea Mathata a amanang le Gastric Acid: Maemong a mang, Famotidine e ka sebelisoa ho thibela mathata a amanang le gastric acid a bakoang ke meriana e kang NSAIDs.
3. Foromo ea litekanyetso:Hangata Famotidine e fumaneha ka mokhoa oa matlapa a nooang le liente, 'me bakuli ba ka e noa ho latela keletso ea ngaka.
4. Maikutlo a Mabe:Ka kakaretso Famotidine e mamelloa hantle, empa litla-morao tse ling li ka hlaha, joalo ka hlooho, ho tsekela, lets'ollo kapa pipitlelano.
5. Litaelo tsa tšebeliso:Ha ba sebelisa Famotidine, bakuli ba lokela ho tsebisa lingaka tsa bona haeba ba e-na le mathata a mang a bophelo kapa ba noa meriana e meng ho qoba ho sebelisana le lithethefatsi.
Akaretsa
Famotidine ke mohanyetsi ea sebetsang oa H2 receptor, haholo-holo e sebelisetsoang ho phekola mafu a amanang le asiti ea gastric, joalo ka lefu la reflux la gastroesophageal le liso tsa peptic. Ka ho fokotsa secretion ea asiti ea gastric, Famotidine e ka imolla matšoao a amanang le eona le ho khothaletsa pholiso. Ha u e sebelisa, u lokela ho latela litaelo tsa ngaka ho netefatsa polokeho le katleho.
COA
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | Phofo e tšoeu kapa e tšoeu | Phofo e Tshweu |
| Boitsebiso ba HPLC | E tsamaellana le referense nako ea ho boloka sehlohlolong | E lumellana |
| Ho potoloha ho itseng | +20.0.-+22.0. | +21. |
| Litšepe tse boima | ≤ 10ppm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Tahlehelo ka ho omisa | ≤ 1.0% | 0.25% |
| Ketapele | ≤3ppm | E lumellana |
| Arsenic | ≤1ppm | E lumellana |
| Cadmium | ≤1ppm | E lumellana |
| Mercury | ≤0. 1ppm | E lumellana |
| Sebaka se qhibilihang | 250.0℃~265.0℃ | 254.7 ~ 255.8 ℃ |
| Masalla ha a tuka | ≤0. 1% | 0.03% |
| Hydrazine | ≤2ppm | E lumellana |
| Boima ba bongata | / | 0.21g/ml |
| Tekanyo e matla | / | 0.45g/ml |
| Assay (Famotidine) | 99.0%~ 101.0% | 99.65% |
| Kakaretso ea lipalo tsa aerobes | ≤1000CFU/g | <2CFU/g |
| Hlobo le Litomoso | ≤100CFU/g | <2CFU/g |
| E.coli | E mpe | E mpe |
| Salmonella | E mpe | E mpe |
| Polokelo | Boloka sebakeng se pholileng le se omisang, qoba khanya e matla. | |
| Qetello | Ea tšoanelehang | |
Mosebetsi
Famotidine ke mohanyetsi oa H2 receptor, haholo-holo e sebelisetsoang ho phekola mafu a amanang le asiti ea gastric. E sebetsa ka ho thibela li-receptor tsa histamine H2 liseleng tsa gastric parietal, ho fokotsa secretion ea asiti ea gastric. Tse latelang ke mesebetsi ea mantlha ea Famotidine:
1. Fokotsa tlhahiso ea asiti ea ka mpeng:Famotidine e fokotsa haholo secretion ea asiti ea gastric ka ho hanyetsa li-receptor tsa H2, ho thusa ho imolla matšoao a bakoang ke asiti e feteletseng ea gastric.
2. Phekolo ea lefu la reflux la gastroesophageal (GERD):Famotidine e ka sebelisoa ho phekola lefu la reflux la gastroesophageal, ho imolla ho otloa ke pelo le ho se thabise ho bakoang ke reflux ea gastric acid.
3. Kalafo ea seso sa peptic:Famotidine e sebelisetsoa ho phekola seso sa ka mpeng le seso sa duodenal, ho khothalletsa pholiso ea seso, le ho fokotsa kotsi ea ho ipheta hape.
4. Thibelo ea secretion ea acid e ka morao ka mor'a ho sebetsa:Ka mor'a ho buuoa ho itseng, Famotidine e ka sebelisoa ho thibela secretion e feteletseng ea asiti ea gastric le ho fokotsa kotsi ea mathata a ka mor'a ho buuoa.
5. Fokotsa matšoao a amanang le asiti ea mala:Famotidine e ka thusa ho imolla matšoao a bakoang ke asiti ea ka mpeng, joalo ka bohloko ba ka mpeng, ho hloleha ha lijo le ho ruruha.
Tšebeliso
Famotidine hangata e fumaneha ka mokhoa oa matlapa a nooang kapa liente, 'me tekanyo e khethehileng le makhetlo a tšebeliso li lokela ho fetoloa ho latela keletso ea ngaka ea hau.
Maikutlo a Mabe
Famotidine ka kakaretso e mamelloa hantle, empa litla-morao tse ling li ka hlaha, joalo ka hlooho, ho tsekela, lets'ollo, kapa ho patoa.
Qetellong, Famotidine ke mohanyetsi ea sebetsang oa H2 receptor, haholo-holo e sebelisetsoang ho phekola mafu a amanang le acidic acid, ho thusa bakuli ho imolla matšoao le ho khothalletsa pholiso. Ha u e sebelisa, u lokela ho latela litaelo tsa ngaka ho netefatsa polokeho le katleho.
Kopo
Tšebeliso ea Famotidine e shebane haholo le kalafo ea mafu a amanang le asiti ea gastric, ho kenyelletsa le lintlha tse latelang:
1. Lefu la Reflux la Gastroesophageal (GERD):Famotidine e sebelisoa ho imolla matšoao a bakoang ke acid reflux, joalo ka ho otloa ke pelo, ho khutla ha asiti, le bohloko ba sefuba. E imolla matšoao ana ka ho fokotsa secretion ea asiti ka mpeng.
2. Peptic ulcer:Famotidine e sebelisoa ho phekola seso sa ka mpeng le seso sa duodenal, ho thusa ho khothaletsa pholiso ea liso le ho kokobetsa bohloko bo amanang le tsona.
3. Thibelo ea mafu a amanang le asiti ea mala:Famotidine e ka sebelisoa ho thibela mafu a amanang le asiti ea mala a bakoang ke lithethefatsi tse kang li-nonsteroidal anti-inflammatory drugs (NSAIDs), haholo-holo ho bakuli ba kotsing e kholo.
4.Zollinger-Ellison syndrome:Famotidine e ka boela ea sebelisoa ho phekola lefu lena le sa tloaelehang, le bakang secretion e feteletseng ea asiti ea mala.
5.Postoperative gastric acid management:Ka mor'a ho buuoa ho itseng, Famotidine e ka sebelisoa ho laola secretion ea asiti ea gastric le ho fokotsa kotsi ea mathata a ka mor'a ho buuoa.
Tšebeliso
Famotidine hangata e fanoa ka mokhoa oa matlapa a molomo. Bakuli ba lokela ho e nka ho latela keletso ea ngaka ea bona. Tekanyo le makhetlo a tšebeliso li tla fapana ho latela boemo bo itseng.
Lintlha
Ha ba sebelisa Famotidine, bakuli ba lokela ho tsebisa lingaka tsa bona haeba ba e-na le mathata a mang a bophelo kapa ba noa meriana e meng ho qoba ho sebelisana le lithethefatsi. Ho feta moo, le hoja Famotidine e khona ho laola ho ntšoa ha asiti ea ka mpeng ka katleho, bakuli ba lokela ho ea ngakeng haeba matšoao a tsoela pele kapa a mpefala.
Qetellong, Famotidine ke mohanyetsi ea sebetsang oa H2 receptor e sebelisoang haholo ho phekola mafu a amanang le gastric acid, ho thusa bakuli ho imolla matšoao le ho khothalletsa pholiso. E lokela ho sebelisoa tlas'a tataiso ea ngaka ho netefatsa polokeho le katleho.
Sephutheloana le thomello
