Terbinafine Hydrochloride High Purity API Material CAS 78628-80-5
Sharaxaada Alaabta
Terbinafine Hydrochloridewaa dawo antifungal ah oo loo isticmaalo daawaynta caabuqyada kala duwan. Caadi ahaan waa qaab kaniiniyo ama kiriimyo. terbinafine hydrochloride waa dawo antifungal ah oo waxtar leh oo loo isticmaalo in lagu daweeyo caabuqyada fangas ee kala duwan. Haddi ay wax ka qabanayso cagaha ciyaartooyga ama caabuqyada ciddiyaha fangas, daawadani waxay u shaqaysaa iyada oo caqabad ku ah wax soo saarka ergosterol waxayna bixisaa ikhtiyaaro la mariyo iyo afka ah si ay ugu habboonaato iyo waxtarka.
COA
| WAXYAABAHA | HEERKA | NATIIJADA IMTIXAANKA |
| Qiimayn | 99% | waafaqsan |
| Midabka | budo cad | waafaqsan |
| ur | Ma jiro ur gaar ah | waafaqsan |
| Cabbirka walxaha | 100% dhaaf 80mesh | waafaqsan |
| Luminta qalajinta | ≤5.0% | 2.35% |
| Hadhaaga | ≤1.0% | waafaqsan |
| Bir culus | ≤10.0pm | 7ppm |
| As | ≤2.0pm | waafaqsan |
| Pb | ≤2.0pm | waafaqsan |
| Hadhaaga sunta cayayaanka | xun | xun |
| Wadarta tirada saxanka | ≤100cfu/g | waafaqsan |
| Khamiirka & Caaryada | ≤100cfu/g | waafaqsan |
| E.Coli | xun | xun |
| Salmonella | xun | xun |
| Gabagabo | Waafaqi sifada | |
| Kaydinta | Lagu kaydiyaa meel qabow & qallalan, ka fogow iftiinka xooggan iyo kulaylka | |
| Nolosha shelf | 2 sano marka si fiican loo kaydiyo | |
Shaqada
1.Terbinafine hydrochloride a allyla antifungal synthetic. Dabiiciga waa lipophilic heer sare ah waxayna u egtahay inay ku ururto maqaarka, cidiyaha, iyo unugyada dufanka leh.
2.Terbinafine · HCl oo xubin ka ah fasalka allyl ee antifungals, ayaa lagu ogaaday in uu yahay xakameyn gaar ah oo ka mid ah ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase waa enzim ay sii daayaan fangaska dermatophyte si ay u burburiyaan Squalene, taas oo faragelinaysa shaqada xuubka unugyada iyo isku dhafka derbiga.
3.Terbinafine hydrochloride waxay leedahay saameyn fungicidal ah oo ku saabsan fungi maqaarka iyo saameynta xannibaadda ee Candida albicans. Waxay ku habboon tahay cudurrada maqaarka iyo ciddiyaha ee uu keeno fangaska dusha sare, sida giraanta, gooryaanka jirka, gooryaanka femur, gooryaanka cagaha, gooryaanka ciddiyaha iyo Candida albicans caabuqa maqaarka ee uu keeno Trichophyton rubrum, Microsporum canis iyo Flocculus epidermidis.
Codsiga
Terbinafine hydrochloride waa budo crystalline cad oo si xor ah u milmay methan iyo dichlorome, ku milma ethanol, iyo wax yar oo biyo ah. Sida allylamines kale, terbinafine waxay joojisaa isku-dhafka ergosterol iyadoo la xakameynayo squalene epoxidase,
ensaymes oo ka mid ah dariiqa synthesis xuubka unugga fangas. Sababtoo ah terbinafine waxay ka hortagtaa beddelka ofsqualene ee lanosterol, ergosterol lama samayn karo. Tan waxaa loo maleynayaa inay beddesho xuubabka unugyada, taasoo keenta lysis unug fangas ah.
1. Terbinafine Hcl ayaa inta badan waxtar u leh kooxda dermatophyte ee fungi.
2. Kareem ahaan 1% ama budo ahaan, waxa si dug ah loogu isticmaalaa infekshannada maqaarka sare sida cuncunka jock-ka (tinea cruris),
cagaha ciyaartooyga (tinea pedis), iyo noocyada kale ee gooryaanka (tinea corporis). Kareemka Terbinafine wuxuu shaqeeyaa qiyaastii kala bar wakhtiga loo baahan yahay
by antifungals kale.
3. Kiniinada afka laga qaato ee 250mg ayaa inta badan loo qoraa daawaynta onychomycosis, caabuqa cidiyaha fangas, sida caadiga ah dermatophyte
ama noocyada Candida. Caabuqyada ciddiyaha fangasku waxay ku yaalliin qoto dheer ciddiyaha hoostiisa ee cirridka kaas oo daawaynta dusha loo mariyo
ma awoodaan inay galaan qadar ku filan. Kaniiniyada ayaa laga yaabaa, marar dhif ah, inay keenaan hepatotoxicity, sidaa darteed bukaanada ayaa looga digay tan iyo
waxaa lagula socon karaa baaritaanada shaqada beerka. Waxaa la darsay wax ka bedelka maamulka afka.
4. Terbinafine waxa laga yaabaa inuu kiciyo ama ka sii daro lupus erythematosus maqaarka hoostiisa. Dadka qaba lupus erythematosus waa in
marka hore kala hadal khataraha suurtogalka ah dhakhtarkooda ka hor inta aan la bilaabin daawaynta.
Alaabooyinka La Xiriira
Warshada Newgreen waxa kale oo ay siisaa Amino acids sida soo socota:
Xidhmada & Bixinta
