●Waa maxayAshwagandha ?
Ashwagandha, oo sidoo kale loo yaqaan Indian ginseng (Ashwagandha), ayaa sidoo kale loo yaqaan cherry jiilaalka, withania somnifera. Ashwagandha waxaa lagu aqoonsan yahay awoodaheeda antioxidant-ka ee muhiimka ah iyo sifooyinka kor u qaadista difaaca. Intaa waxaa dheer, ashwagandha ayaa loo isticmaalay in lagu kiciyo hurdo.
Ashwagandha waxaa ku jira alkaloids, lacttones steroid, withanolides iyo birta. Alkaloids-yadu waxay leeyihiin hawlo dejineed, xanuun joojiye iyo hoos u dhiga cadaadiska dhiigga. Withanolides waxay leeyihiin saameyn anti-bararka waxayna joojin karaan koritaanka unugyada kansarka. Waxa kale oo loo isticmaali karaa Caabuqyada daba-dheeraada sida lupus iyo rheumatoid arthritis-ka, yaraynta leucorrhea, hagaajinta shaqada galmada, iwm, iyo sidoo kale waxay gacan ka geystaan soo kabashada cudurrada daba-dheeraada. Ashwagandha sidoo kale waxaa loo aqoonsan yahay awooddeeda antioxidant ee muhiimka ah iyo sifooyinka kor u qaadista difaaca jirka.
Sida laga soo xigtay cilmi-baaris ay sameeyeen saynisyahano,ashwagandhasoosaarku wuxuu leeyahay saameyno badan oo isku mid ah sida ginseng, oo ay ku jiraan xoojinta, kicinta, iyo hagaajinta difaaca aadanaha. Soosaaray Ashwagandha waxaa lagu farsamayn karaa daawo loogu talagalay daaweynta cillad la'aanta kacsiga ragga ka dib markii lagu daro dhirta kale ee saameynta aphrodisiac (sida maca, cawska turner, guarana, xidid kava iyo epimedium Shiinaha, iwm.).
●Waa maxay Faa'iidooyinka Caafimaad ee ku jiraAshwagandha?
1.Ka hortagga kansarka
Waqtigan xaadirka ah, waxaa la xaqiijiyay in laga soosaaray Ashwagandha ay leedahay 5 habab oo lagu dilo unugyada kansarka, dhaqaajiso hidda-wadaha xakameynaya burada p53, kor u qaadista kicinta gumeysiga, kicinta dariiqa dhimashada unugyada kansarka, kicinta dariiqa apoptosis ee unugyada kansarka, iyo nidaaminta G2- M DNA waxyeelada;
2.Ilaalinta neerfaha
Soosaarka Ashwagandha wuxuu xakameyn karaa saameynta sunta ah ee scopolamine ee neerfaha iyo unugyada glial; kor u qaado shaqada antioxidant ee maskaxda; iyo in la yareeyo waxyeelada oksaydhka ee ay keento streptozotocin;
Tijaabada diiqada, waxa kale oo la ogaaday inAshwagandhasoosaarku wuxuu kor u qaadi karaa koritaanka axonal ee unugyada neuroblastoma bini'aadamka, kor u qaadista dib u soo kabashada iyo dib u soo kabashada axon iyo dendrites ee kiliyaha maskaxda iyadoo la saarayo borotiinka β-amyloid (marka lagu daro, borotiinka β-amyloid ayaa hadda loo arkaa inuu yahay molecule dhexe ee bilawga cudurka Alzheimers);
3.Mechanism ka-hortagga cudurka macaanka
Waqtigan xaadirka ah, waxay u muuqataa in saameynta hypoglycemic ee Ashwagandha ay ku dhowdahay in la barbardhigo daawooyinka hypoglycemic (glibenclamide). Ashwagandha waxay yarayn kartaa tusaha dareenka insulin ee jiirarka waxayna yaraynaysaa caabbinta insulinta. Waxay kor u qaadi kartaa qaadashada gulukooska iyada oo loo marayo tuubbooyinka muruqyada lafaha iyo adipocytes, taas oo hoos u dhigta sonkorta dhiigga.
4.Bakteeriyada
Ashwagandhasoosaarku wuxuu leeyahay saameyn weyn oo xakameynaya bakteeriyada Gram-positive, oo ay ku jiraan Staphylococcus iyo Enterococcus, Escherichia coli, Salmonella typhi, Proteus mirabilis, Citrobacter freundii, Pseudomonas aeruginosa, iyo Klebsiella pneumoniae. Intaa waxaa dheer, Ashwagandha ayaa sidoo kale lagu muujiyay in ay saameyn ku leedahay fangaska, oo ay ku jiraan Aspergillus flavus, Fusarium oxysporum, iyo Fusarium verticillium, iyada oo loo marayo biqilka spore iyo koritaanka hyphae. Markaa Ashwagandha waxay hadda u muuqataa inay iska caabin u leedahay bakteeriyada, fungi, iyo protozoa.
5.Ilaalinta Wadnaha
Ashwagandhasoosaarku wuxuu kicin karaa factor nukliyeerka erythroid-related factor 2 (Nrf2), firfircooni wejiga II enzymes detoxification, iyo baabi'inta apoptosis unugga ay sababtay Nrf2. Isla mar ahaantaana, Ashwagandha waxay sidoo kale hagaajin kartaa shaqada hematopoietic. Iyada oo loo marayo daawaynta ka-hortagga, waxay dib u bilaabi kartaa oxidation myocardial oxidation/antioxidation ee jidhka waxayna kor u qaadaysaa dheelitirka labada nidaam ee apoptosis-ka unugyada / apoptosis-ka-hortagga unugyada. Waxaa sidoo kale la ogaaday in ashwagandha ay sidoo kale nidaamin karto wadnaha wadnaha ee ay keento doxorubicin.
6.Dhiiri diiqada
Ashwagandha waxay yareyn kartaa unugyada T waxayna kor u qaadi kartaa cytokines Th1 ee ay keento walbahaarka. Tijaabooyinka kiliinikada ee bini'aadamka, ayaa la xaqiijiyay in ay yareyn karto hormoonnada cortisol iyada oo aan wax saameyn ah lahayn. Dhirta dhirta badan ee loo yaqaan EuMil (ay ku jirto ashwagandha) waxay wanaajin kartaa gudbiyeyaasha monoamine ee maskaxda. Waxa kale oo ay yarayn kartaa dulqaad la'aanta gulukooska iyo cillad la'aanta galmada ee ragga ee uu keeno walbahaarka.
7.Anti-bararka
Waxaa hadda la rumeysan yahay inashwagandhaXididka xididku wuxuu leeyahay saameyn toos ah oo xakameynaya calaamadaha caabuqa oo ay ku jiraan buro necrosis factor (TNF-α), nitric oxide (NO), noocyada oksijiinta falcelinta (ROS), nukliyeerka nukliyeerka (NFk-b), iyo interleukin (IL-8 & 1β). Isla mar ahaantaana, waxay daciifin kartaa kinase ERK-12, p38 borotiinka fosfooraska oo ay keentay phosphorylation phosphorylation (PMA), iyo C-Jun amino-terminal kinase.
8.Hagaajinta Shaqada Galmada Labka/Dumarka
Warqad lagu daabacay "BioMed research international" (IF3.411/Q3) ee 2015 ayaa daraasad ku samaysay saameynta ashwagandha ee shaqada galmada dumarka. Gabagabadu waxay taageertaa in laga soosaaray ashwagandha loo isticmaali karo in lagu daweeyo cillad la'aanta galmada ee dumarka, taas oo badbaado leh oo aan lahayn waxyeelo.
Ashwagandha waxay kordhin kartaa feejignaanta iyo dhaqdhaqaaqa shahwada labka ah, waxay kordhisaa testosterone, hormoonka luteining, hoormoonka kicinta follicle, waxayna saameyn togan ku leedahay calaamado kala duwan oo oksaydh ah iyo calaamadaha antioxidant.
●QABADKA CUSUBAshwagandhaSoo saar budada/kaabsulaha/ xabagta
Waqtiga boostada: Nov-08-2024
