N-Acetylneuraaminic acid budada soo saaraha Newgreen N-Acetylneuramine
Sharaxaada Alaabta
N-acetylneuraminic acid (NANA, Neu5Ac) waa qayb muhiim ah oo ka mid ah glycoconjugates, sida glycolipids, glycoproteins, iyo proteoglycans (sialoglycoproteins), kuwaas oo siinaya sifada xidhitaanka xulashada ee qaybaha glycosylated. Neu5Ac waxaa loo isticmaalaa in lagu barto biochemistry, dheef-shiid kiimikaad iyo qaadashada gudaha vivo iyo in vitro. Neu5Ac waxaa loo isticmaali karaa horumarinta nanocarriers.
COA
| Walxaha | Tilmaamaha | Natiijooyinka | |
| Muuqashada | budo cad | budo cad | |
| Qiimayn |
| Gudub | |
| ur | Midna | Midna | |
| Cufnaanta dabacsan (g/ml) | ≥0.2 | 0.26 | |
| Khasaare xagga qalajinta | ≤8.0% | 4.51% | |
| Hadhaaga dabka | ≤2.0% | 0.32% | |
| PH | 5.0-7.5 | 6.3 | |
| Celceliska miisaanka kelli | <1000 | 890 | |
| Biraha culus (Pb) | ≤1PPM | Gudub | |
| As | ≤0.5PPM | Gudub | |
| Hg | ≤1PPM | Gudub | |
| Tirada bakteeriyada | ≤1000cfu/g | Gudub | |
| Colon Bacillus | ≤30MPN/100g | Gudub | |
| Khamiirka & Caaryada | ≤50cfu/g | Gudub | |
| Bakteeriyada Pathogenic | xun | xun | |
| Gabagabo | U hoggaansamaan qeexitaanka | ||
| Nolosha shelf | 2 sano marka si fiican loo kaydiyo | ||
Shaqada
1. Hagaajinta garaadka iyo xusuusta ilmaha
N-Acetylneuraminic acid waa qayb muhiim ah oo ka mid ah dhismaha gangliosides ee maskaxda. Maaddada sialic acid ee xuubka unugyada dareemayaasha ayaa 20 jeer ka badan unugyada kale. Sababtoo ah gudbinta macluumaadka maskaxda iyo socodsiinta dareenka dareemayaasha waa in lagu gartaa synapses, iyo N-Acetylneuraminic acid waa nafaqo maskaxeed oo ka shaqeysa xuubabka unugyada maskaxda iyo synapses, sidaas darteed N-Acetylneuraminic acid waxay kor u qaadi kartaa horumarinta xusuusta iyo sirdoonka. Daraasaduhu waxay ogaadeen in kordhinta nuxurka N-Acetylneuraminic acid ee cuntada naasnuujinta ay kordhin doonto nuxurka N-Acetylneuraminic acid ee maskaxda ilmaha, heerka muujinta hidde-sidaha la xidhiidha waxbarashada ayaa sidoo kale kor u kacaya, taas oo kor u qaadeysa awoodeeda waxbarasho iyo xusuusta. Dhallaanka, waxa ku jira N-Acetylneuraminic acid waa 25% oo keliya waxa ku jira caanaha naaska.
2. Waallida ka hortagga waayeelka
N-Acetylneuraminic acid waxay leedahay difaac iyo saameyn xasilinta unugyada dareemayaasha. Ka dib markii borotiinka ku yaal dusha sare ee xuubka unugyada dareemayaasha lagu daro N-Acetylneuraminic acid, ma hoos u dhigi karo protease ka baxsan. Qaar ka mid ah cudurrada neerfaha, sida waallida hore ee waayeelka iyo schizophrenia, waxay yareyn doontaa nuxurka N-Acetylneuraminic acid ee dhiigga ama maskaxda, iyo ka dib markii laga soo kabsado daaweynta daroogada, N-Acetylneuraminic acid content wuxuu ku soo laaban doonaa si caadi ah, taas oo muujinaysa in N-Acetylneuraminic acid ay ka qayb qaadato. habka dheef-shiid kiimikaadka unugyada dareemayaasha.
3. Aqoonsi diid
Inta u dhaxaysa molecules iyo unugyada, inta u dhaxaysa unugyada iyo unugyada, iyo inta u dhaxaysa unugyada iyo dunida dibadda, N-Acetylneuraminic acid ee dhamaadka silsiladda sonkorta waxay u adeegi kartaa goobta aqoonsiga ama maaskaro goobta aqoonsiga. N-Acetylneuraminic acid ee ku xiran dhamaadka glycosides iyada oo loo marayo bonds glycosidic waxay si wax ku ool ah uga hortagi kartaa qaar ka mid ah goobaha antigenic ee muhiimka ah iyo calaamadaha aqoonsiga ee dusha unugyada, taas oo ka ilaalinaysa saccharides-ka in la aqoonsado oo hoos u dhigo habka difaaca ee ku xeeran.
Codsiyada
1. N-Acetylneuraminic acid waxaa loo isticmaalaa soo saarista neuraminidase inhibitors kala duwan, glycolipids iyo alaabta kale ee synthetically ka soo jeeda bioactive. Waxa loo isticmaali karaa kab nafaqo ahaan.
2. N-Acetylneuraminic acid waxa ay door muhiim ah ka ciyaartaa kabitaanka cuntada sida glyconutrient. Waxay nidaamisaa borotiinka dhiigga nuska nolosha, acidification, dhexdhexaadinta sunta kala duwan, adhesion unug iyo ilaalinta glycoprotein lysis. Waxa loo isticmaali karaa cunto lagu daro.
3. N-Acetylneuraminic acid waxaa loo isticmaali karaa sidii reagent bilow ah oo loogu talagalay isku-darka walxaha biochemical ee daawooyinka. Waxa loo isticmaali karaa sida qurxinta.
Xidhmada & Bixinta
