Itraconazole Pharmaceutical Darajada Traconazole Budada Antifungal Itraconazole Qiimaha
Sharaxaada Alaabta
Itraconazolewaa antifungal triazole oo af-firfircoon oo afka laga qaato oo lagu tilmaamay in loo isticmaalo daawaynta maqaarka maqaarka, siilka iyo nidaamka mycoses. Bukaanjiifka difaaca jirka iyo AIDS-ka, itraconazole ayaa la muujiyay in ay si weyn u yareyso dhacdooyinka soo noqoshada ee qoorgooyaha cryptococcal.
COA
| WAXYAABAHA | HEERKA | NATIIJADA IMTIXAANKA |
| Qiimayn | 99% Itraconazole | waafaqsan |
| Midabka | budo cad | Csoo bandhigo |
| ur | Ma jiro ur gaar ah | Csoo bandhigo |
| Cabbirka walxaha | 100% dhaaf 80mesh | Csoo bandhigo |
| Luminta qalajinta | ≤5.0% | 2.35% |
| Hadhaaga | ≤1.0% | waafaqsan |
| Bir culus | ≤10.0pm | 7ppm |
| As | ≤2.0pm | Csoo bandhigo |
| Pb | ≤2.0pm | Csoo bandhigo |
| Hadhaaga sunta cayayaanka | xun | xun |
| Wadarta tirada saxanka | ≤100cfu/g | waafaqsan |
| Khamiirka & Caaryada | ≤100cfu/g | waafaqsan |
| E.Coli | xun | xun |
| Salmonella | xun | xun |
| Gabagabo | Waafaqi sifada | |
| Kaydinta | Lagu kaydiyaa meel qabow & qallalan, ka fogow iftiinka xooggan iyo kulaylka | |
| Nolosha shelf | 2 sano marka si fiican loo kaydiyo | |
Shaqada
1) Itraconazole waxa uu leeyahay hawlo kala duwan oo ka balaadhan fluconazole (laakin maaha sida voriconazole ama posaconazole). Gaar ahaan, waxay ka hortagtaa Aspergillus oo aan fluconazole ahayn.
2) Waxa kale oo loo qoraa caabuqyada habdhiska, sida aspergillosis, candidiasis, iyo cryptococcosis.
3) Itraconazole ayaa sidoo kale dhawaan loo sahamiyay sidii wakiilka ka hortagga kansarka ee bukaanka qaba kansarka unugyada basal.
Codsiga
1.Itraconazole waa clotrimazole synthetic si dabiici ah, isagoo ah wakiilka antifungal synthetic ballaaran. Xakameynteeda antimicrobial spectrum iyo habka ka hortagga jeermiska bakteeriyada waxay la mid tahay clotrimazole, laakiin waxay leedahay firfircooni bakteeriyada lidka ku ah Aspergillus.
2.Itraconazole waxay fulisaa saameynteeda fangas-ka-hortagga iyada oo bedesha xuubka unugyada fangas-ka ee leh firfircoonida bakteeriyada lidka ku ah cudurada fangas ee dusha sare iyo qoto dheer. Bakteeriyadeeda bakteeriyada ayaa ka ballaadhan oo ka xoog badan ketoconazole, iyada oo awood u leh in ay joojiso isku-darka ergosterol ee xuubka unugyada fangas, sidaas darteed ciyaarta saamaynta antifungal.
3.Itraconazole waxay ku haboon tahay daaweynta Dermatophytes (Trichophyton, Microsporum, Flocculent Epidermophyton), khamiir [Cryptococcus neoformans, Pityrosporum, Candida (oo ay ku jiraan Candida albicans, Candida glabrata iyo candida krusei)], Aspergillus, Histoplasma, Brasilicdiocdiocsis, Brasilicdiocsis, Brasilicdiocsissis Hormodendrum, Cladosporium, Blastomyces dermatitis iyo noocyada kala duwan ee noocyada kale ee khamiirka iyo fungi. Itraconazole ma awoodo inay joojiso koritaanka Rhizopus iyo Mucor.
Alaabooyinka la xidhiidha
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Xidhmada & Bixinta
