Budada Benfotiamine ee Dabiiciga ah ee Tayada Sare leh Budada Benfotiamine
Sharaxaada Alaabta
Sifooyinka Kiimikada Lipophilic Si ka duwan fiitamiin B1 (thiamine) biyaha ku milma ee caadiga ah, benfotiam waa lipophilic sare. Tani waxay u oggolaaneysaa inay si fudud u gasho xuubabka noolaha sida xuubabka unugyada. Hantidani waxay ka timid kooxaha benzylic iyo phosphoryl ee qaab dhismeedka kiimikada, kuwaas oo beddela sifooyinka jireed iyo kiimikaad ee molecule-ka, kor u qaadaysa milmaheeda iyo qulqulka goobaha dufanka leh. Xasiloonida Benfotine waa mid deggan marka loo eego xaalado deegaan oo kala duwan. Waxay aad uga adkeysi badan tahay deegaanka acidic acid gastric acid marka loo eego thiamine caadiga ah, taas oo ka dhigaysa mid aad u degan mareenka, taas oo kor u qaadaysa nuugista iyo ka faa'iidaysiga jidhka. Xaaladaha kaydinta caadiga ah, sida jawiga qabow iyo qalalan, benfotiamine waxay sii hayn kartaa xasilloonideeda muddo dheer.
COA
| Walxaha | Tilmaamaha | Natiijooyinka |
| Muuqashada | budo cad | U hogaansama |
| Dalbo | Sifada | U hogaansama |
| Qiimayn | ≥99.0% | 99.5% |
| Dhadhamiya | Sifada | U hogaansama |
| Khasaare xagga qalajinta | 4-7 (%) | 4.12% |
| Wadarta Dambas | 8% ugu badnaan | 4.85% |
| Birta culus | ≤10 (ppm) | U hogaansama |
| Arsenic (As) | 0.5pm ugu badnaan | U hogaansama |
| Leedhka (Pb) | 1ppm ugu badnaan | U hogaansama |
| Meerkuri (Hg) | 0.1pm ugu badnaan | U hogaansama |
| Wadarta tirada saxanada | 10000cfu/g Max | 100cfu/g |
| Khamiirka & Caaryada | 100cfu/g Max | ＞20cfu/g |
| Salmonella | xun | U hogaansama |
| E.Coli. | xun | U hogaansama |
| Staphylococcus | xun | U hogaansama |
| Gabagabo | CoU dir USP 41 | |
| Kaydinta | Ku kaydi meel si fiican u xiran oo leh heerkul hoose oo joogto ah oo aan lahayn iftiin cadceed toos ah. | |
| Nolosha shelf | 2 sano marka si fiican loo kaydiyo | |
Shaqada
Isticmaalka iyo Codsiyada Kahortagga iyo daawaynta dhibaatooyinka sonkorowga: Benfotiamine waxaa ugu horayn loo isticmaalaa daawaynta si looga hortago loona yareeyo dhibaatooyinka macaanka. Deegaanka sonkorta badan ee bukaanka sonkorowga qaba waxay u horseedi kartaa taxane ah cillado dheef-shiid kiimikaad ah, soo saarista alaabada dhamaadka glycation sare ee xad dhaafka ah, taas oo dhaawici karta dareemayaasha, xididdada dhiigga, iyo unugyada kale. Benfotiamine waxay dhaqaajin kartaa transketolase, oo ah enzyme muhiim ah oo ku jira dariiqa pent phosphate, kaas oo yarayn kara wax soo saarka AGE-yada, si looga hortago loona daweeyo dhibaatooyinka sonkorowga sida sonkorowga neuropathy, retinopathy sonkorowga, iyo nefathy macaanka. Tusaale ahaan, cilmi-baaristu waxay muujisay in kabidda bukaanka macaanka ee benfotiamine ay hagaajin karto xawaaraha socodka dareemayaasha waxayna yareyn kartaa calaamadaha xanuunka neuropathy sida kabuubyada gacmaha iyo cagaha. Neuroprotection: Waxa kale oo ay leedahay saamaynta neuroprotective, iyo marka lagu daro codsigeeda neuropathy macaanka, waxaa laga yaabaa inay leedahay qiime daweyn oo suurtagal ah noocyada kale ee dhaawaca dareemayaasha ama cudurrada neurodegenerative. Tusaale ahaan, qaar ka mid ah moodooyinka tijaabada ah ee dhaawaca dareemaha durugsan, benfiamine waxay kor u qaadi kartaa dib-u-soo-nooleynta dareemayaasha iyo hagaajinta waxayna yareyn kartaa waxyeelada ay keento falcelinta bararka ee neerfaha.
Codsiga
Dhinaca garashada, benfiamine waxa laga yaabaa inay caawiso hagaajinta xusuusta iyo dareenka. Tan waxaa lagu gaari karaa habab kala duwan sida ilaalinta unugyada dareemayaasha iyo ilaalinta dheef-shiid kiimikaadka caadiga ah ee neurotransmitters. Daraasadaha hordhaca ah qaarkood waxay ogaadeen in dadka waayeelka ah, ku kabashada benfotiamine ay hagaajin karto calaamadaha cilladda garashada ilaa xad. Alaabooyinka Daryeelka Caafimaadka Kaabayaasha Nafaqada ee Goobta Sida qaab wax ku ool ah oo fitamiin B1 ah, benfotiamine waxaa loo isticmaali karaa kab nafaqo ahaan. Waa doorasho wanaagsan dadka laga yaabo inay nuugaan fiitamiin B1, sida kuwa qaba cudurrada caloosha iyo mindhicirka ama khudradda kuwaas oo halis ugu jira yaraanta fitamiin B1. Waxay bixisaa bioavailability ka sarreeya kaaga caadiga ah, si wax ku ool ah u kabto baahida jidhka ee fitamiin B1, ilaalinta dheef-shiid kiimikaadka tamarta caadiga ah, iyo taageeridda shaqada habdhiska dareenka. Tusaale ahaan, oo ay ku jiraan benfotine-ka qaar ka mid ah dheellitirka fiitamiinnada ee dhammaystiran waxay kor u qaadi kartaa waxtarka nafaqada guud ee alaabta.
Alaabooyinka la xidhiidha
Xidhmada & Bixinta
