Budada Baclofen ee Dabiiciga ah ee Tayada Sare leh ee Baclofen

Baclofen, oo sidoo kale loo yaqaan Becomphin, Becomphin, iyo Li Luxing, magaca dawadu waa chirosol, Liolexin, chloraminobutyric acid, waa nooc ka mid ah gamma-aminobutyric acid, daroogada spasmolytic, ee ficilka habka dhexe ee neerfayaasha maskaxda iyo laf-dhabarka laf-dhabarka. nasiyo murqaha, dejiye. Waxay joojin kartaa sii-deynta amino acids-ka firfircoon sida glutamic acid iyo aspartate iyadoo kicinaysa soo-dhoweeyaha, sidaas darteed waxay joojinaysaa gudbinta hal-abuurka synaptic iyo multi-synaptic reflex ee maskaxda iyo xudunta lafdhabarta ee habka dhexe ee neerfayaasha, si ay u ciyaaraan a doorka spasmotic. Kiliinik ahaan, waxa loo isticmaalay sidii diyaargarowga jinsiyadeed ee daawaynta muruqa Buugga Kiimikada ee baaba'a ilaa bartamihii 1960-meeyadii. Daraasadihii ugu dambeeyay ayaa sidoo kale lagu ogaaday in badeecadani ay si weyn u yareeyn karto dib-u-soo-celinta gastroesophageal iyo hagaajinta astaamaheeda, si wax ku ool ah u nafiso calaamadaha dystonia ee carruurta, iyo daaweynta cilladda kaadida ka dib dhaawaca laf-dhabarka dhexe ee lafdhabarta. Intaa waxaa dheer, codsiga kiliinikada ee daaweynta cirbadeynta intrathecal waxay sii wanaajin kartaa waxtarka bukaan-socodka iyo hagaajinta qiyaasta daawada wakhti kasta si loo dejiyo saameynta daaweynta. 10-kii sano ee la soo dhaafay, codsiga kiliinikada ee baclofen ee murqaha dhexe ee nasashada ayaa sameeyay horumar weyn, gaar ahaan daaweynta baxnaaninta dareemayaasha si loo yareeyo murqaha murqaha iyo xanuun joojinta.