Newgreen Supply High QualityBrown Algae Extract 98% Fucoidan Powder

Basa:

1. Inovandudza chirwere chemudumbu

Yakawanikwa kuti mhedzisiro yepolysaccharide pazvirwere zvegastric yainyanya kuratidzwa muzvikamu zvitatu zvinotevera: (1) Polysaccharide yakanga ine simba rekubvisa Helicobacter pylori, ichidzivisa kupararira kweHelicobacter pylori uye kudzivisa kusungirirwa kwayo negastric mucosa; (2) Iine mhedzisiro yekudzivirira gastric mucosa uye kurapa gastric ulcer, uye ine yakanaka yekuderedza mhedzisiro padoro uye zvinodhaka-induced gastric mucosal kukuvara uye chisingaperi gastric ulcer; (3) Fucoidan ine anti-gastric cancer effect, inogona kutadzisa kuwanda kwegastric cancer maseru, kuderedza mhedzisiro yechemotherapy, uye kuvandudza hupenyu hwevarwere.

2. Anticoagulant effect

Fucoidan ine akawanda biological mabasa, asi ayo anticoagulant basa ndiyo inonyanya kudzidzwa. Zvidzidzo zvakaratidza kuti mapolysaccharides anotorwa kubva kune akasiyana Marine brown algae ane madhigirii akasiyana eanticoagulant chiitiko. Semuyenzaniso, ari polysaccharides kubva uye akaratidza yakakwirira dhigirii anticoagulant basa, uye anticoagulant basa uye aiva hafu kuti yekare, asi anenge hapana anticoagulant basa.

3. Antithrombotic effect

Mumuenzaniso wekuyedza wemhuka mhenyu, iyo polysaccharide yefucoidan ine inhibitory mhedzisiro pane ese ari maviri venous thrombosis uye arterial thrombosis. Rocha et al. vakawana kuti polysaccharide yakanga isina anticoagulant basa mu vitro, asi yakaratidza pachena antithrombotic effect mumuenzaniso wemhuka wekugadzira venous thrombosis, uye mhedzisiro yacho yaienderana nenguva, inosvika pakakwirira mushure me8h yekutonga. Iyo anticoagulant chiitiko chepolysaccharide ingangove yakabatana nekukurudzira kugadzirwa kweheparin sulfate nemaseru endothelial.

4. Antiviral effect

Zvidzidzo zvakaratidza kuti sulfated polysaccharides (kusanganisira fucoidan polysaccharides) inoratidza antiviral chiitiko zvese mu vivo uye in vitro. Hayashi et al. akadzidza kudzivirira kwefucoidan paherpes simplex virus (HSV). Vakaona kuti fucoidan inogona kudzivirira mbeva kubva kuhutachiona hweHSV, uye yakataura kuti fucoidan inogona kudzivirira HSV kutapukira nekudzivisa zvakananga kudzokororwa kwehutachiona uye kuwedzera innate uye kuwana immune immune basa. Panguva imwecheteyo, yakawanikwa zvakare kuti iyo polysaccharide yakaratidza antiviral basa rinopesana neHSV-1 uye HSV-2. Hidari et al. yakashuma kuti fucoidan inogona kunyatso kuvharidzira hutachiona hwe dengue virus type 2 (DEN2), uye yakaratidza kuti fucoidan inosunga kuDEN2 particles uye inopindirana nekuputira kwayo glycoprotein. Iyo haina yakananga passivation maitiro pane virions, uye ayo antiviral maitiro ndeye kuvharidzira kuumbwa kwehutachiona cytiocytes nekudzivisa adsorption yehutachiona.

5. Anti-tumor effect

Fucoidan inoonekwa seyakasikwa anti-cancer agent, uye basa rayo rekurwisa bundu rave richitaurwa zvakanyanya uye zvakanyanya. Alekseyenko et al. akadzidza basa rekurwisa-bundu refucoidan pamakonzo anotambura kubva kuLewis lung adenocarcinoma, uye akadyisa fucoidan pachiyero che10mg/kg kumakonzo, zvichiita kuti pave nepakati anti-bundu basa uye anti-tumor metastasis effect. Zvimwe zvidzidzo zvakawanawo kuti bundu inhibition rate ye fucoidan pamhuka 5 dzine S180 sarcoma yaiva 30%, uye sarcoma yemhuka mbiri yakadzikira zvachose. Mundiro yepetri inenge 10,000 masero emukenza wekoloni akabatwa nealgae polysaccharides yakawanikwa kubva kukelp, makumi mashanu muzana emasero ekenza akafa mushure memaawa makumi maviri nemana, uye anenge ese masero ekenza akafa mushure memaawa makumi manomwe nemaviri. Hyun et al. vakawana kuti polysaccharide yedombo algae inogona kumisa zvakanyanya kukura kweHCT-15 colon cancer maseru. Mushure mekurapwa kweHCT-15 cell line nedombo algae polysaccharide, zviitiko zveapoptotic senge DNA breakage, chromosome aggregation, uye kuwedzera kwe subdiploid masero muG1 chikamu chakaonekwa.

6. Antioxidant madhara

Nhamba huru yezviyedzo zve in vitro zvakaratidza kuti iyo polysaccharide yedombo algae ine yakakosha antioxidant basa, imhando yemhando yeantioxidant, uye inogona kudzivirira zvinobudirira chirwere chinokonzerwa nemahara radicals. Costa et al. yakabudiswa sulfated polysaccharides kubva kune 11 marudzi emvura inopisa yegungwa, iyo yose yakanga ine antioxidant basa, kukwanisa kuumba ferrous chelates uye kuderedza simba, 5 iyo yakanga ine simba rekubvisa hydroxyl radicals, uye 6 yaive nekukwanisa kubvisa peroxy radicals. Micheline et al. yakashuma kuti polysaccharides kubva kune algae inogona kutadzisa kuumbwa kwehydroxyl radical uye superoxide radical.

7. Kuita kwekudzivirira muviri

Fucoidan ine mabasa akawanda ekudzivirira zvirwere, kusanganisira anti-complement chiitiko, anti-inflammatory response uye immunomodulatory effects. Tissot et al. yakasimbisa kuti polysaccharide ye fucoite inogona kuvharidzira puroteni inokwana muserum yevanhu, nokudaro ichidzivisa kuparara kwemakwai matsvuku eropa anokonzerwa nekushandiswa kwekuzadzisa, uye kudzivisa kushandiswa kwekugadzirisa nekudzivisa danho rekutanga renzira yekudzidzira (kusanganisira chikamu chekutanga chekuzadzisa, chikamu chechipiri uye chikamu chechina). Yang et al. akawana kuti fucoidan inogona kusarudza kurambidza kutaura kweinducible nitric oxide synthase mumasero anopisa uye ine anti-inflammatory activity. Mizuno et al. yakashandisa co-culture system ye intestinal epithelial Caco-2 masero uye macrophage RAW264.7 kuti iongorore maitiro ekurwisa-kupisa kwezvinhu zvekudya, uye zvigumisiro zvakaratidza kuti polysaccharide yeS. japonicum inogona kukurudzira kugadzirwa kwe tumor necrosis factor.α muRAW264.7, nokudaro ichidzivisa mRNA kutaura kwe interleukin muCaco-2 masero.

8. Kuvandudza urume hwemurume

Kutungamirirwa kwefucoidan kunogona kuvandudza sperm quality uye uwandu nekuvandudza ropa metabolites uye intestinal microbiota. Vatsvagiri vakawana kuti mushure mekupihwa negungwa repolysaccharides, iwo maratidziro emajini ane hukama nespermatogenesis akawedzera zvakanyanya muma testes emakonzo. Panguva imwecheteyo, pakanga paine kuwirirana kwakanaka pakati peintestinal microbiota uye metabolites yeropa. Nekugadzirisa izvo zviviri, iyo polysaccharide yefucoite yakavandudza metabolites ye testis, yakawedzera kuchengetedzwa kwe antioxidant, uye kumusoro-yakadzora danho rekutaura remajini ane hukama mumasero ehutachiona, nokudaro zvichibatsira kuspermatogenesis nekuvandudzwa kwemhando.