Newgreen Factory Supply Topotecan Hydrochloride High Quality 99% Topotecan Hydrochloride Powder
Product Description
Topotecan Hydrochloride mushonga wechemotherapy unoshandiswa kunyanya kurapa mamwe marudzi egomarara. Ndiyo hydrochloride fomu ye topotecan, topoisomerase inhibitor iyo inoshanda zvakanyanya nekudzivisa kuita kweDNA topoisomerase I.
Notes:
Paunenge uchishandisa Topotecan, varwere vanofanira kunge vari pasi pekutungamirirwa kwachiremba, kunyanya kune varwere vane chiropa uye itsvo kusagadzikana kana mamwe matambudziko ehutano. Kuongororwa ropa nguva dzose kunodiwa panguva yekurapa kutarisa zvinogona kuitika.
Mukupedzisa, Topotecan Hydrochloride yakakosha anticancer mushonga, unonyanya kushandiswa kurapa gomarara reovarian uye diki kenza yemapapu, uye ine yakakosha kukiriniki yekushandisa kukosha.
COA
| Items | Zvinotsanangurwa | Results |
| Chitarisiko | Kunze-chena kana chena poda | White Powder |
| HPLC Kuzivikanwa | Zvinoenderana nereferensi chinhu chikuru chepamusoro chekuchengetedza nguva | Conforms |
| Kutenderera chaiko | +20.0.-+22.0. | +21. |
| Heavy metals | ≤ 10ppm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Kurasikirwa pakuomeswa | ≤ 1.0% | 0.25% |
| Tungamira | ≤3ppm | Conforms |
| Arsenic | ≤1ppm | Conforms |
| Cadmium | ≤1ppm | Conforms |
| Mercury | ≤0. 1ppm | Conforms |
| Melting point | 250.0℃~265.0℃ | 254.7~255.8℃ |
| Residue pakubatidza | ≤0. 1% | 0.03% |
| Hydrazine | ≤2ppm | Conforms |
| Bulk density | / | 0.21g/ml |
| Tapped density | / | 0.45g/ml |
| Assay(Topotecan Hydrochloride） | 99.0%~ 101.0% | 99.65% |
| Total aerobes kuverenga | ≤1000CFU/g | <2CFU/g |
| Mold & Yeast | ≤100CFU/g | <2CFU/g |
| E.coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Storage | Chengetedza munzvimbo inotonhorera & yakaoma, chengetedza kure nechiedza chakasimba. | |
| Mhedziso | Qualified | |
Basa
Topotecan Hydrochloride mushonga wechemotherapy unoshandiswa kunyanya kurapa mamwe marudzi egomarara. Iyo topoisomerase inhibitor ine anotevera maitiro ekuita uye mabasa:
Basa:
1.Topoisomerase inhibition: Topotecan inokanganisa kudzokorora kweDNA uye kunyora nekudzivisa basa re topoisomerase I. Kudzivisa uku kunotungamirira pakuputsika kweketani dzeDNA, nokudaro kudzivirira kupararira kwekenza masero.
2.Antitumor basa: Topotecan inonyanya kushandiswa kurapa gomarara reovarian, kenza diki yemapapu uye mamwe marudzi e lymphoma. Inogona kushandiswa senzira yekurapa yekutanga kana sechipiri chekurapa mushure mekunge mamwe marapiro akundikana.
3.Cell cycle specificity: Mhedzisiro yeTopotecan pasero cycle inowanzoitika muchikamu cheS uye G2, iyo inoita kuti ive nekuuraya kwakasimba pamasero ekenza mune imwe nhanho yekuwedzera kwesero.
4.Combination therapy: Topotecan inogona kushandiswa pamwe chete nemamwe chemotherapy mishonga kuwedzera anti-bundu mhedzisiro uye kugadzirisa mhinduro yekurapa kwemurwere.
5.Relieve Zviratidzo: Mune zvimwe zviitiko, kushandiswa kweTopotecan kunogona kubatsira kubvisa zviratidzo zvine chokuita nekenza uye kuvandudza hupenyu hwemurwere.
Notes:
Topotecan inogona kukonzera mimwe migumisiro yechirwere, kusanganisira asi kwete kushungurudza, kurutsa, kuneta, leukopenia, etc. Paunenge uchishandisa mushonga uyu, varwere vanoda kuongororwa uye kutarisirwa pasi pekutungamirirwa kwachiremba.
Mukupedzisa, Topotecan Hydrochloride mushonga unoshanda weanticancer uyo unoshandisa antitumor mhedzisiro kunyanya kuburikidza nekuvharirwa kweDNA topoisomerase I.
Application
Topotecan Hydrochloride mushonga wechemotherapy unoshandiswa kunyanya kurapa mamwe marudzi egomarara. Izvi zvinotevera mashandisirwo ayo makuru:
1.Ovarian cancer: Topotecan inowanzoshandiswa kurapa kenza inowanzoitika, kunyanya kune varwere mushure mokunge mamwe marapirwo (akadai seplatinum-based chemotherapy) akundikana. Inogona kushandiswa sechinhu chimwe chete kana musanganiswa nemamwe madhiragi.
2.Small cell lung cancer: Mushonga uyu unoshandiswawo mukurapa kenza yemapapu diki, kazhinji senzira yechipiri yekurapa, kunyanya kana chirwere ichi chikadzokera mushure mekutanga chemotherapy.
3.Mamwe Magomarara: Kunyange zvazvo Topotecan inonyanya kushandiswa kwegomarara reovarian uye kenza yemapapu diki, iri kuongororwawo mune mamwe makiriniki ekuedzwa kune mamwe marudzi egomarara, akadai sekenza yechibereko, pancreatic cancer, uye mamwe marudzi e lymphoma.
4.Miedzo yekiriniki: Topotecan iri kuongororwawo mumakiriniki ekuyedzwa kwegomarara akasiyana siyana kuti adzidze kushanda kwayo uye kuchengetedzeka mune dzakasiyana nzira dzekurapa.
5.Combination Therapy: Mune zvimwe zviitiko, Topotecan inogona kushandiswa pamwe chete nemamwe madhiragi echemotherapy kana anonangwa kurapa mishonga yekuwedzera kurapa.
Notes:
Paunenge uchishandisa Topotecan, varwere vanofanira kunge vari pasi pekutungamirirwa kwachiremba, kunyanya kune varwere vane chiropa uye itsvo kusagadzikana kana mamwe matambudziko ehutano. Kuongororwa ropa nguva dzose kunodiwa panguva yekurapa kutarisa zvinogona kuitika.
Mukupedzisa, Topotecan Hydrochloride ine kukosha kwekushandisa mukurapwa kwegomarara, kunyanya mukutonga kwegomarara reovarian rinowanzoitika uye kenza diki yemapapu.
Package & Delivery
