Itraconazole Pharmaceutical Giredhi Traconazole Powder Antifungal Itraconazole Mutengo
Product Description
Itraconazoleis an orally-active triazole antifungal inoratidzwa kuti ishandiswe mukurapa dermal, vaginal uye systemic mycoses. Mune varwere vane immunocompromised uye AIDS, itraconazole yakaratidzwa kuderedza zvakanyanya chiitiko chekudzokazve kwe cryptococcal meningitis.
COA
| ZVINHU | STANDARD | TEST RESULT |
| Assay | 99% Itraconazole | Conforms |
| Color | Upfu chena | Conforms |
| Kunhuwa | Hapana kunhuhwirira kwakakosha | Conforms |
| Chikamu saizi | 100% inopfuura 80mesh | Conforms |
| Kurasikirwa pakuomeswa | ≤5.0% | 2.35% |
| Residue | ≤1.0% | Conforms |
| Heavy metal | ≤10.0ppm | 7ppm |
| As | ≤2.0ppm | Conforms |
| Pb | ≤2.0ppm | Conforms |
| Mushonga wezvipembenene wasara | Negative | Negative |
| Yese plate count | ≤100cfu/g | Conforms |
| Yeast & Mold | ≤100cfu/g | Conforms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Mhedziso | Ita zvinoenderana neSpecification | |
| Storage | Yakachengetwa munzvimbo Inotonhorera & Yakaoma, Ramba Kure Nechiedza Chakasimba uye Kupisa | |
| Sherufu hupenyu | 2 years pakachengetwa zvakanaka | |
Basa
1) Itraconazole ine huwandu hwakawanda hwekuita kupfuura fluconazole (asi kwete yakakura sevoriconazole kana posaconazole). Kunyanya, inoshanda kurwisa Aspergillus iyo fluconazole isiri.
2) Inonyorerwawo kune systemic zvirwere, senge aspergillosis, candidiasis, uye cryptococcosis.
3) Itraconazole zvakare ichangobva kuongororwa senge anticancer agent kune varwere vane basal cell carcinoma.
Application
1.Itraconazole is artificially synthetic clotrimazole, iri wide-spectrum synthetic antifungal agent. Iro antimicrobial spectrum uye antimicrobial mechanism yakafanana neclotrimazole, asi ine simba rinorwisa mabhakitiriya rinopesana neAspergillus.
2.Itraconazole ine anti-fungal mhedzisiro kuburikidza nekushandura fungal cell membrane permeability ine antibacterial chiitiko kupesana nepamusoro uye yakadzika fungal pathogens. Iro antibacterial spectrum yakafara uye yakasimba kudarika ketoconazole, ichikwanisa kuvharidzira ergosterol synthesis yefungal cell membrane, nokudaro kutamba antifungal effect.
3.Itraconazole inokodzera kurapa kweDermatophytes (Trichophyton, Microsporum, Flocculent Epidermophyton), Yeast [Cryptococcus neoformans, Pityrosporum, Candida (kusanganisira Candida albicans, Candida glabrata uye candida krusei)], Aspergillus, Paracoccus neoformans, Pityrosporum, Candida (kusanganisira Candida albicans, Candida glabrata uye candida krusei)], Aspergillus, Paracoccus neoformans. schenckii, Hormodendrum, Cladosporium, Blastomyces dermatitidis uye akasiyana marudzi emamwe marudzi embiriso uye fungi. Itraconazole haikwanisi kudzivisa kukura kweRhizopus uye Mucor.
Zvigadzirwa zvinoenderana
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