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Fa'amatalaga o oloa
Famotidine o le H2 receptor antagonist, e masani ona faʻaaogaina e togafitia ai faʻamaʻi e fesoʻotaʻi ma le gastric acid. E fa'agata ai fa'ama'i o le histamine H2 i totonu o sela o le gastric parietal cell, fa'aitiitia ai le fa'aliloina o le gatric acid, ma fa'amama ai fa'ailoga e mafua mai i le tele o le gastric acid. O loʻo taua i lalo se faʻamatalaga auiliili ile Famotidine:
Vaega Autu ma Galuega
1. Mechanism: Famotidine fa'agata le fa'aliloina o le gastric acid ma fa'aitiitia le ga'o i totonu o le manava e ala i le filifilia fa'afete'ena'i o le H2 receptors i luga o sela parietal gastric.
2. Fa'ailoga:
- Gastroesophageal Reflux Disease (GERD): Fa'aaogā e fa'amama ai fa'ailoga e mafua mai le su'esu'e o le suka, e pei o le mu o le fatu ma le toe fa'afo'i ga'o.
-Peptic ulcer: faʻaaogaina e togafitia ai le maʻi o le manava ma le maʻi o le duodenal ma faʻamalosia le faʻamaloloina o le maʻi.
- Puipuiga ole Gatric Acid-Related Disorders: I nisi tulaga, Famotidine e mafai ona faʻaaogaina e puipuia ai faʻafitauli faʻaletonu ole gatric acid e mafua mai i vailaʻau e pei ole NSAIDs.
3. Fomu fua:Famotidine e masani lava ona maua i le tuʻu gutu ma tui, ma e mafai e tagata gasegase ona ave e tusa ai ma le fautuaga a le fomaʻi.
4. Tali leaga:Famotidine e masani lava ona talia lelei, ae o nisi o aʻafiaga e mafai ona tupu, e pei o le ulu, niniva, manava manava poʻo le manava.
5. Puipuiga mo le faʻaaogaina:A fa'aogaina le Famotidine, e tatau i tagata gasegase ona logoina a latou foma'i pe a iai nisi fa'afitauli o le soifua maloloina po'o o lo'o inuina isi vaila'au e aloese ai mai le fa'aogaina o vaila'au.
Aotele
O le Famotidine ose fa'ama'i lelei H2, e masani ona fa'aaogaina e togafitia ai fa'ama'i e feso'ota'i ma le gastric acid, e pei o le gastroesophageal reflux ma'i ma'i peptic. E ala i le faʻaitiitia o le faʻamalo o le gatric acid, e mafai e le Famotidine ona faʻamalolo faʻamaoniga e fesoʻotaʻi ma faʻaleleia le faʻamalolo. A faʻaaogaina, e tatau ona e mulimuli i faʻatonuga a le fomaʻi ina ia mautinoa le saogalemu ma le aoga.
COA
| Aitema | Fa'amatalaga | I'uga |
| Fa'aaliga | Pa'epa'e pa'epa'e pe pa'epa'e pa'epa'e | Pa'u Pa'epa'e |
| Fa'ailoga HPLC | Ia ogatasi ma le faasinomaga taimi maualuga o le taofiga o mea | Fa'atasi |
| Ta'amilosaga fa'apitoa | +20.0.-+22.0. | +21. |
| Metala mamafa | ≤ 10ppm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Ma'imau ile fa'amago | ≤ 1.0% | 0.25% |
| Ta'ita'i | ≤3ppm | Fa'atasi |
| Arsenic | ≤1ppm | Fa'atasi |
| Cadmium | ≤1ppm | Fa'atasi |
| Mercury | ≤0. 1ppm | Fa'atasi |
| Liu liusuavai | 250.0℃~265.0℃ | 254.7~255.8 ℃ |
| Toega ile mu | ≤0. 1% | 0.03% |
| Hydrazine | ≤2ppm | Fa'atasi |
| Fa'atosina tele | / | 0.21g/ml |
| Tapped density | / | 0.45g/ml |
| Su'ega (Famotidine) | 99.0%~ 101.0% | 99.65% |
| Aofa'i atoa taulia | ≤1000CFU/g | <2CFU/g |
| Maliu & Faafefete | ≤100CFU/g | <2CFU/g |
| E.coli | Le lelei | Le lelei |
| Salmonella | Le lelei | Le lelei |
| Teuina | Teu i se nofoaga malulu & fa'agogo, fa'amama le malamalama malosi. | |
| Fa'ai'uga | Agavaa | |
Galuega
Famotidine o le H2 receptor antagonist, e masani ona faʻaaogaina e togafitia ai faʻamaʻi e fesoʻotaʻi ma le gastric acid. E galue e ala i le taofiofia o le histamine H2 receptors i sela parietal gastric, faʻaitiitia ai le faʻamalo ole gatric acid. O loʻo taua i lalo galuega autu a Famotidine:
1. Fa'aitiitia le fa'amalo ole gatric acid:Famotidine e matua fa'aitiitia ai le fa'aliloina o le gatric acid e ala i le fa'afefe H2 receptors, fesoasoani e fa'amama fa'ailoga e mafua mai i le tele o le gatric acid.
2. Togafitiga ole ma'i fa'ama'i fa'ama'i (GERD):Famotidine e mafai ona faʻaaogaina e togafitia ai le maʻi o le gastroesophageal reflux, faʻamalolo le manava ma le faʻalavelave e mafua mai i le gastric acid reflux.
3. Togafitiga ole ma'i ma'i peptic:Famotidine e faʻaaogaina e togafitia ai le maʻi o le manava ma le maʻi o le duodenal, faʻaleleia le faʻamalologa o le maʻi, ma faʻaitiitia le lamatiaga o le toe tupu.
4.Prevention o postoperative gastric acid secretion:A maeʻa nisi o taotoga, e mafai ona faʻaogaina le Famotidine e puipuia ai le tele o le gatric acid secretion ma faʻaitiitia ai le lamatiaga o faʻalavelave faʻafuaseʻi.
5. Fa'amama fa'ailoga e feso'ota'i ai le manava o le manava:E mafai e le Famotidine ona fesoasoani e fa'amama fa'ailoga e mafua mai i le manava o le manava, e pei o le tiga o le manava, le manava ma le fula.
Fa'aoga
Famotidine e masani lava ona maua ile tu'u gutu po'o tui, ma ole fua fa'apitoa ma taimi ole fa'aoga e tatau ona fetu'una'i ile fautuaga a lau foma'i.
Tali Leaga
Famotidine e masani lava ona talia lelei, ae o nisi o aʻafiaga e ono tupu, e pei o le ulu, niniva, manava manava, poʻo le maʻi.
I le faʻaiʻuga, o le Famotidine o se faʻamaʻi lelei o le H2 receptor antagonist, e masani ona faʻaaogaina e togafitia ai faʻamaʻi faʻamaʻi gaʻo, fesoasoani i tagata mamaʻi e faʻamalolo faʻailoga ma faʻaleleia le faʻamalolo. A faʻaaogaina, e tatau ona e mulimuli i faʻatonuga a le fomaʻi ina ia mautinoa le saogalemu ma le aoga.
Fa'aaogāga
O le faʻaaogaina o le Famotidine e masani ona taulaʻi i le togafitiga o faʻamaʻi e fesoʻotaʻi ma le gastric acid, e aofia ai vaega nei:
1. Gastroesophageal Reflux Disease (GERD):Famotidine e faʻaaogaina e faʻamalolo ai faʻamaoniga e mafua mai i le acid reflux, e pei o le manava, faʻamaʻi faʻamaʻi, ma le tiga o le fatafata. E fa'amama ai nei fa'ailoga e ala i le fa'aitiitia o le fa'alilo o le manava o le manava.
2. Ma'i papala:Famotidine e faʻaaogaina e togafitia ai le maʻi o le manava ma le maʻi o le duodenal, e fesoasoani i le faʻaleleia o le faʻamalologa o le maʻi ma faʻamalolo ai tiga ma faʻafitauli.
3.Prevention o faʻamaʻi e fesoʻotaʻi ma gastric acid:Famotidine e mafai ona fa'aoga e puipuia ai fa'ama'i fa'ama'i e a'afia i le ga'o e mafua mai i vaila'au e pei ole nonsteroidal anti-inflammatory drugs (NSAIDs), aemaise i gasegase e lamatia.
4. Ma'i Zollinger-Ellison:Famotidine e mafai foi ona faʻaaogaina e togafitia ai lenei faʻamaʻi e seasea ona tupu, lea e mafua ai le faʻafefe tele o le manava o le manava.
5. Postoperative gastric acid pulega:A maeʻa ni taotoga faʻapitoa, e mafai ona faʻaaoga Famotidine e pulea ai le gaʻo gaʻo ma faʻaitiitia ai le lamatiaga o faʻalavelave faʻafuaseʻi.
Fa'aoga
Famotidine e masani lava ona tuʻuina atu ile tuʻuga ole laulau. E tatau i tagata ma'i ona inu e tusa ai ma fautuaga a latou foma'i. Ole fua ole fa'aoga ma taimi ole fa'aoga ole a eseese ile tulaga fa'apitoa.
Fa'amatalaga
A fa'aaogaina le Famotidine, e tatau i tagata gasegase ona logoina a latou foma'i pe a iai nisi fa'afitauli o le soifua maloloina po'o o lo'o inuina isi vaila'au e aloese ai mai le fa'aogaina o vaila'au. E le gata i lea, e ui lava e mafai e le Famotidine ona pulea lelei le faʻamalo o le gatric acid, e tatau i tagata gasegase ona sailia togafitiga faafomaʻi pe a faʻaauau pea pe faʻaleagaina faʻaʻailoga.
I le faʻaiʻuga, o le Famotidine o se faʻamaʻi lelei o le H2 receptor antagonist lea e masani ona faʻaaogaina i le togafitiga o faʻamaʻi faʻamaʻi gaʻo, fesoasoani i tagata mamaʻi e faʻamalolo faʻamaoniga ma faʻaleleia le faʻamalolo. E tatau ona faʻaaogaina i lalo o le taʻitaʻiga a se fomaʻi e faʻamautinoa ai le saogalemu ma le aoga.
afifi & Tiliva
