Ifunguro Ryinshi Ibyiciro Byinshi Pranlukast Ifu nigiciro cyiza
Ibisobanuro ku bicuruzwa
Pranlukast ni imiti yo mu kanwa ikoreshwa cyane mu kuvura indwara za allergique, cyane cyane rhinite ya allergique na asima. Nibihitamo leukotriene reseptor antagonist ishobora guhagarika neza ingaruka za leukotriène, bityo bikagabanya ingaruka za allergique no gutwika.
Ibintu by'ingenzi n'imikorere
1. Uburyo bukoreshwa:Pranlukast ihitamo kurwanya reseptor ya CysLT1, ikabuza guhagarika umwuka, gusohora ururenda no kongera imiyoboro y'amaraso iterwa na leukotriène (nka cysteine leukotrienes), bityo bikagabanya ibimenyetso bya allergique na asima.
2. Ibyerekana:
- Indwara ya allergique:Ikoreshwa mugukuraho ibimenyetso nkizuru ryizuru, izuru ritemba, kuniha, nibindi biterwa nudukoko, imyanda, nibindi.
- Asima:Nkumuti wongeyeho kuvura asima, ifasha kugenzura ibimenyetso bya asima no kugabanya inshuro yibitero.
3. Ifishi ikoreshwa:Ubusanzwe Pranlukast iboneka muburyo bwibinini byo mu kanwa, abarwayi bashobora gufata nkuko inama za muganga zibiteganya.
Mu gusoza, Pranlukast ni imiti igabanya ubukana bwa allergique, ikoreshwa cyane mu kuvura indwara ya rinite ya allergique na asima, igabanya ingaruka ziterwa na allergique hamwe n’umuriro mu kurwanya imiti ya leukotriene. Mugihe uyikoresha, ugomba gukurikiza ubuyobozi bwa muganga kugirango umenye umutekano kandi neza.
COA
| Ibintu | Ibisobanuro | Ibisubizo |
| Kugaragara | Ifu yera cyangwa yera | Ifu yera |
| Kumenyekanisha HPLC | Bihuye nibisobanuro ibintu nyamukuru impinga yo kugumana igihe | Guhuza |
| Kuzenguruka byihariye | +20.0 。- + 22.0。 | +21。 |
| Ibyuma biremereye | ≤ 10ppm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Gutakaza kumisha | ≤ 1.0% | 0,25% |
| Kuyobora | ≤3ppm | Guhuza |
| Arsenic | ≤1ppm | Guhuza |
| Cadmium | ≤1ppm | Guhuza |
| Mercure | ≤0. 1ppm | Guhuza |
| Ingingo yo gushonga | 250.0 ℃ ~ 265.0 ℃ | 254.7 ~ 255.8 ℃ |
| Ibisigisigi byo gutwikwa | ≤0. 1% | 0.03% |
| Hydrazine | ≤2ppm | Guhuza |
| Ubucucike bwinshi | / | 0.21g / ml |
| Ubucucike | / | 0.45g / ml |
| Suzuma ran Pranlukast） | 99.0% ~ 101.0% | 99,62% |
| Indege zose zirabaze | 0001000CFU / g | <2CFU / g |
| Ibishushanyo & Umusemburo | ≤100CFU / g | <2CFU / g |
| E.coli | Ibibi | Ibibi |
| Salmonella | Ibibi | Ibibi |
| Ububiko | Ubike ahantu hakonje & humye, gumana urumuri rukomeye. | |
| Umwanzuro | Yujuje ibyangombwa | |
Imikorere
Pranlukast ni imiti yo mu kanwa ikoreshwa cyane mu kuvura asima na rinite ya allergique. Nibihitamo leukotriene reseptor antagonist ikumira neza ingaruka za leukotriène, bityo bikagabanya ibimenyetso bifitanye isano na allergie na asima. Ibikurikira nibikorwa byingenzi bya Pranlukast:
1. Ingaruka zo kurwanya inflammatory:Pranlukast ifasha kugenzura ibimenyetso bya asima muguhagarika ingaruka za leukotriène no kugabanya ingaruka ziterwa no guhumeka.
2. Kunoza imikorere yubuhumekero:Mugabanye kugabanuka no gutwika inzira zumuyaga, Pranlukast irashobora kunoza imikorere yubuhumekero bwabarwayi ba asima kandi bikagabanya kubaho kwishongora no guhumeka neza.
3. Kuraho ibimenyetso bya allergie:Pranlukast ikoreshwa kandi mu kuvura rinite ya allergique kandi irashobora kugabanya ibimenyetso bya allergie nko kunanuka kw'izuru, izuru ritemba, kuniha, n'ibindi.
4. Kwirinda indwara ya asima:Gukoresha igihe kirekire Pranlukast birashobora gufasha kwirinda ibitero bikaze bya asima, cyane cyane kubarwayi bafite asima iterwa na siporo.
5. Gukoresha hamwe nibindi biyobyabwenge:Pranlukast irashobora gukoreshwa ifatanije nindi miti irwanya asima (nka corticosteroide ihumeka) kugirango yongere imbaraga zo kuvura.
Muri make, umurimo wingenzi wa Pranlukast nugukuraho ibimenyetso bya asima na rhinite ya allergique no kuzamura imibereho yabarwayi mukurwanya reseptor ya leukotriene. Mugihe uyikoresha, ugomba gukurikiza ubuyobozi bwa muganga kugirango umenye umutekano kandi neza.
Gusaba
Ikoreshwa rya Pranlukast ryibanda cyane cyane ku kuvura indwara ziterwa na allergie, harimo n'ibi bikurikira:
1. Indwara ya allergique:Pranlukast ikoreshwa mu kugabanya ibimenyetso bya rinite ya allergique iterwa n'intanga, umukungugu, umukungugu w'inyamaswa, n'ibindi, nko kuzunguruka mu mazuru, izuru ritemba, kuniha no kwishongora mu mazuru. Igabanya ibisubizo byumuriro wizuru ryizuru mukurwanya ingaruka za leukotriène.
2. Asima:Pranlukast ikoreshwa nk'ubuvuzi bufatika bwa asima kugirango ifashe kugenzura ibimenyetso bya asima no kugabanya inshuro n'uburemere bwibitero bya asima. Irashobora gukoreshwa ifatanije nindi miti irwanya asima (nka corticosteroide ihumeka na bronchodilator) kugirango yongere imbaraga zo kuvura.
3. Imyitozo iterwa na Bronchoconstriction:Pranlukast irashobora kandi gukoreshwa mubihe bimwe na bimwe kugirango wirinde imyitozo iterwa na bronchoconstriction, ifasha abakinnyi hamwe nabantu bakora cyane kugenzura imyuka yabo mbere yimyitozo.
4. Indwara Zidakira Allergique:Pranlukast irashobora kandi gufatwa nkigice cyo kuvura mugucunga indwara zimwe na zimwe zidakira.
Ikoreshwa
Ubusanzwe Pranlukast iboneka muburyo bwibinini byo munwa, abarwayi bagomba gufata bakurikije inama za muganga, mubisanzwe rimwe kumunsi.
Inyandiko
Iyo ukoresheje Pranlukast, abarwayi bagomba kubwira muganga wabo niba bafite ibindi bibazo byubuzima cyangwa bafata indi miti kugirango birinde ibiyobyabwenge. Byongeye kandi, mugihe Pranlukast ishobora gufasha kugenzura ibimenyetso bya allergie na asima, ntabwo igamije kuvura indwara ya asima ikaze.
Mu gusoza, Pranlukast ni imiti igabanya ubukana bwa allergique, ikoreshwa cyane mu kuvura indwara ya allergique na asima, ifasha abarwayi kuzamura imibereho yabo. Mugihe uyikoresha, ugomba gukurikiza ubuyobozi bwa muganga kugirango umenye umutekano kandi neza.
Gupakira & Gutanga
