Terbinafine Hydrochloride Yera Yuzuye API Ibikoresho CAS 78628-80-5
Ibisobanuro ku bicuruzwa
Terbinafine Hydrochlorideni imiti igabanya ubukana ikoreshwa mu kuvura indwara zitandukanye. Mubisanzwe muburyo bwa tableti cyangwa cream. terbinafine hydrochloride ni imiti igabanya ubukana ikoreshwa mu kuvura indwara zitandukanye. Yaba ikemura ibirenge by'abakinnyi cyangwa indwara zifata imisumari, iyi miti ikora ibangamira umusaruro wa ergosterol kandi itanga uburyo bwo gukoresha no gukoresha umunwa muburyo bworoshye kandi bunoze.
COA
| INGINGO | STANDARD | IGISUBIZO CY'IKIZAMINI |
| Suzuma | 99% | Guhuza |
| Ibara | Ifu yera | Guhuza |
| Impumuro | Nta mpumuro idasanzwe | Guhuza |
| Ingano ya Particle | 100% batsinze 80mesh | Guhuza |
| Gutakaza kumisha | ≤5.0% | 2.35% |
| Ibisigisigi | ≤1.0% | Guhuza |
| Icyuma kiremereye | ≤10.0ppm | 7ppm |
| As | ≤2.0ppm | Guhuza |
| Pb | ≤2.0ppm | Guhuza |
| Ibisigisigi byica udukoko | Ibibi | Ibibi |
| Umubare wuzuye | ≤100cfu / g | Guhuza |
| Umusemburo & Mold | ≤100cfu / g | Guhuza |
| E.Coli | Ibibi | Ibibi |
| Salmonella | Ibibi | Ibibi |
| Umwanzuro | Guhuza nibisobanuro | |
| Ububiko | Bibitswe muri Cool & Ahantu humye, Komeza wirinde urumuri rukomeye nubushyuhe | |
| Ubuzima bwa Shelf | Imyaka 2 iyo ibitswe neza | |
Imikorere
1.Terbinafine hydrochloride sintetike ya allyla antifungal. Ni lipofilique cyane muri kamere kandi ikunda kwiyegeranya muruhu, imisumari, hamwe nuduce twinshi.
2.Terbinafine · HCl umunyamuryango wa allyl class ya antifungal, byagaragaye ko ari inzitizi yihariye ya synthesis ya ergosterol ikoresheje kubuza squalene epoxidase. Squalene epoxidase ni enzyme irekurwa na dermatophyte fungi kugirango isenye Squalene, ibangamira imikorere ya selile na synthesis.
3.Terbinafine hydrochloride igira ingaruka zifata ibihumyo byuruhu ningaruka zo kubuza Candida albicans. Irakwiriye kwandura uruhu n imisumari iterwa nibihumyo bitagaragara, nk'inzoka, inzoka zo mu mubiri, inzoka zo mu maguru, inzoka zo mu birenge, inzoka zo mu nzara na Candida albicans kwanduza uruhu rwatewe na Trichophyton rubrum, Microsporum canis epidermidis ya Flocculus.
Gusaba
Terbinafine hydrochloride ni ifu yera ya kristaline yera yoroha cyane muri metani na dichlorome, gushonga muri Ethanol, kandi bigashonga gato mumazi. Kimwe na allylamine, terbinafine ibuza synthesis ya ergosterol muguhagarika epoxidase ya squalene,
enzyme igizwe na fungal selile membrane synthesis inzira. Kuberako terbinafine irinda ihinduka rya squalene kuri lanosterol, ergosterole ntishobora guhuzwa. Ibi biratekerezwa guhindura selile membrane selile, bigatera lysis selile.
1. Terbinafine Hcl igira akamaro cyane mumatsinda ya dermatophyte yibihumyo.
2. Nka cream cyangwa ifu ya 1%, ikoreshwa cyane cyane kwandura uruhu rwimbere nka jock itch (tinea cruris),
ikirenge cyumukinnyi (tinea pedis), nubundi bwoko bwinzoka (tinea corporis). Amavuta ya Terbinafine akora mugihe cyigice gisabwa
nizindi antifungali.
3. Ibinini byo mu kanwa 250mg bikunze gutegekwa kuvura onychomycose, kwandura imisumari ya fungal, mubisanzwe na dermatophyte
cyangwa ubwoko bwa Candida. Indwara zifata imisumari ziri munsi yumusumari muri cicicle aho bivura cyane
ntibashobora gucengera muburyo buhagije. Ibinini birashobora, gake, gutera hepatotoxicity, abarwayi rero baburirwa ibi kandi
irashobora gukurikiranwa no gupima imikorere yumwijima. Ubundi buryo bwo kuyobora umunwa bwarigishijwe.
4. Terbinafine irashobora gutera cyangwa kwiyongera subacute cutaneous lupus erythematosus. Abantu bafite lupus erythematosus bagomba
banza uganire kubibazo bishoboka na muganga wabo mbere yo gutangira kuvura.
Ibicuruzwa bifitanye isano
Uruganda rushya kandi rutanga aside Amino kuburyo bukurikira:
Gupakira & Gutanga
