Ubushakashatsi bwerekana ko abantu bagera kuri miliyoni 537 bakuze ku isi bafite diyabete yo mu bwoko bwa 2, kandi iyo mibare iriyongera. Umubare munini w'isukari mu maraso uterwa na diyabete urashobora gutera indwara nyinshi, zirimo indwara z'umutima, kubura amaso, kunanirwa kw'impyiko, n'ibindi bibazo bikomeye by'ubuzima. Byose birashobora kwihuta cyane gusaza.
Tetrahydrocurcumin, ikomoka ku mizi ya turmeric, yerekanwe mu bushakashatsi bw’ubuvuzi kugira ngo ifashe kugabanya ibintu byinshi bishobora gutera diyabete yo mu bwoko bwa 2 no kugabanya isukari mu maraso ku bantu barwaye diyabete cyangwa diyabete. Kuvura diyabete yo mu bwoko bwa 2 birashobora kugora abarwayi n'abaganga. Mu gihe abaganga basaba indyo, imyitozo ngororamubiri, n'imiti yo kuvura abantu barwaye diyabete yo mu bwoko bwa 2, ubushakashatsi bwerekana kotetrahydrocurcuminirashobora gutanga infashanyo yinyongera.
• Kurwanya Insuline na Diyabete
Iyo turya, isukari yamaraso yacu irazamuka. Ibi byerekana pancreas kurekura imisemburo yitwa insuline, ifasha selile gukoresha glucose kubyara ingufu. Kubera iyo mpamvu, isukari mu maraso irongera igabanuka. Indwara ya diyabete yo mu bwoko bwa 2 iterwa no kurwanya insuline kuko selile zititabira bisanzwe imisemburo. Urwego rw'isukari mu maraso ruguma hejuru, indwara yitwa hyperglycemia. Isukari nyinshi mu maraso irashobora gutera ingorane zifatika, zirimo umutima, imiyoboro y'amaraso, impyiko, ijisho, hamwe na sisitemu y'imitsi, kandi byongera ibyago bya kanseri.
Gutwika bishobora kugira uruhare mu kurwanya insuline no gukomera kwa hyperglycemia ku bantu barwaye diyabete. [8,9] Isukari nyinshi mu maraso itera umuriro mwinshi, byihuta gusaza kandi byongera ibyago byindwara zidakira, nk'indwara z'umutima na kanseri. Glucose irenze kandi itera okiside itera imbaraga, ishobora kwangiza cyane ingirabuzimafatizo. Mubindi bibazo, guhagarika umutima birashobora kuganisha kuri:kugabanuka kwa glucose no gusohora insuline, proteyine na ADN byangiritse, no kongera imiyoboro y'amaraso.
• Ni izihe nyunguTetrahydrocurcuminMuri Diyabete?
Nkibintu bifatika muri turmeric,Tetrahydrocurcuminirashobora gufasha gukumira indwara ya diyabete n’ibyangiritse bishobora gutera muburyo butandukanye, harimo:
1. Gukora PPAR-γ, nigenzura rya metabolike ryongera insuline kandi ikagabanya kurwanya insuline.
2. Ingaruka zo kurwanya inflammatory, harimo no kubuza molekile zerekana ibimenyetso byongera umuriro.
3. Kunoza imikorere nubuzima bwingirabuzimafatizo ya insuline.
4. Kugabanya imiterere yibicuruzwa byanyuma bya glycation kandi bikumira ibyangiritse.
5. Igikorwa cya Antioxydeant, kigabanya guhagarika umutima.
6. Kunoza imyirondoro ya lipide no kugabanya ibimenyetso bimwe na bimwe byerekana imikorere mibi ya metabolike n'indwara z'umutima.
Mu byitegererezo by'inyamaswa,tetrahydrocurcuminyerekana amasezerano mu gufasha gukumira indwara ya diyabete no kugabanya kurwanya insuline.
• Ni izihe nyunguTetrahydrocurcuminMumutima?
Ubushakashatsi bwakozwe mu mwaka wa 2012 bwasohotse mu kinyamakuru mpuzamahanga cya farumasi bwasuzumye ingaruka zatetrahydrocurcuminku mbeba aortic impeta kugirango urebe niba ikomatanyirizo rifite imitima yumutima. Ubwa mbere, abashakashatsi baguye impeta ya aortic hamwe na karbachol, uruganda ruzwiho gutera vasodilation. Hanyuma, imbeba zatewe na homocysteine thiolactone (HTL) kugirango zibuze vasodilasiya. [16] Hanyuma, abashakashatsi bateye imbeba hamwe na 10 μM cyangwa 30 μM zatetrahydrocurcuminugasanga byateye vasodilasiya kurwego rusa na karbachol.
Nk’uko ubu bushakashatsi bubyerekana, HTL itanga vasoconstriction igabanya urugero rwa okiside ya nitric mu maraso kandi ikongera umusaruro wa radicals yubuntu. Kubwibyo,tetrahydrocurcuminigomba kugira ingaruka ku musaruro wa nitide na / cyangwa radicals yubusa kugirango ugarure vasodilation. Kuvatetrahydrocurcuminifite antioxydants ikomeye, irashobora gusiba radicals yubusa.
• Ni izihe nyunguTetrahydrocurcuminMuri hypertension?
Nubwo umuvuduko ukabije wamaraso ushobora kugira impamvu zitandukanye, mubisanzwe biterwa no kugabanuka gukabije kwimiyoboro yamaraso, bigatuma kugabanuka kwamaraso.
Mu bushakashatsi bwakozwe mu 2011, abashakashatsi batanzetetrahydrocurcuminimbeba kugirango urebe uko byagize ingaruka kumuvuduko wamaraso. Kugira ngo imitsi idakora neza, abashakashatsi bifashishije L-arginine methyl ester (L-IZINA). Imbeba zagabanyijwemo amatsinda atatu. Itsinda rya mbere ryakiriye L-IZINA, itsinda rya kabiri ryakiriye tetrahydrocurcumin (ibiro 50mg / kg ibiro byumubiri) na L-IZINA, naho itsinda rya gatatu ryakiratetrahydrocurcumin(100mg / kg uburemere bwumubiri) na L-IZINA.
Nyuma yibyumweru bitatu byo kunywa buri munsi ,.tetrahydrocurcuminitsinda ryagaragaje cyane umuvuduko wamaraso ugereranije nitsinda ryafashe L-IZINA gusa. Itsinda ryahawe dose yo hejuru ryagize ingaruka nziza kurenza itsinda ryahawe igipimo cyo hasi. Abashakashatsi bavuze ko ibisubizo byiza ari byotetrahydrocurcumin'ubushobozi bwo gutera vasodilation.
Igihe cyo kohereza: Ukwakira-10-2024
