NikiReveratrol?
Reveratrol ni uruziko rusanzwe ruboneka mubimera bimwe, imbuto, na vino itukura. Ni uw'itsinda ry'imiterere yitwa polyphenol, ikora nka antioxiday kandi izwiho inyungu zabo zubuzima. Reveveratrol ni nyinshi cyane kuruhu rwinzabibu zitukura kandi zabaye impage nyinshi zatewe ningaruka zishobora kubaho kubintu bitandukanye byubuzima.
Ubushakashatsi bumwe bwerekana ko reveratrol ishobora kuba ifite inyungu zishobora kuba ubuzima bwumutima, kuko ishobora gufasha gushyigikira imiyoboro y'amaraso neza no kuzenguruka. Byongeye kandi, byizwe kubushobozi bwayo bwo kurwanya umuriro-ifishi na Antioxident, bishobora kugira ingaruka kubikorwa byubuzima rusange no gusaza.
Ingabo zakozwe kandi iperereza ku ruhare rushobora gushyigikira gushyigikira ubuzima bw'ubwonko n'imikorere y'ubwonko, ndetse n'ingaruka zayo kuri metabolism n'inyungu zo gucunga ibiro.
Umubiri na shimi ya resveratrol
Reveratrol (3-4'-5-trihydroxystilbene) nicyorezo cya polyphenol kitari flaconol. Izina ryamabati ryayo ni 3,4 ', trihydroxy-1-1,2-Diphenyslene (3,4', trihydlesilbene), formulaire yayo ni c14h12o3, nuburemere bwayo ni 228.25.
Ubutegetsi bwera bugaragara nkumuzungu ifu yumuhondo, impumuro, ihungabanye mumazi, kandi byoroshye mumazi, na methanol, ethanol, na rotyl acetate. Ingingo yo gushonga ni 253-255 ° C, hamwe n'ubushyuhe bwo kugabura ni 261 ° c. Irashobora guhindura umutuku hamwe nigisubizo cya alkaline nkamazi ya amimoni, kandi irashobora kubyitwaramo na Ferric Chlorasiyani-Perrocyami. Uyu mutungo urashobora gukoreshwa mukumenya resveratrol.
Ubutegetsi Busanzwe bufite imiterere ebyiri, cis hanyuma uhindure. Birabaho cyane cyane muburyo bwo guhindura kamere. Inzego ebyiri zirashobora guhuzwa na glucose kugirango zikore cis kandi twohereze ibiruhuko glycosides. Cis- na trans-reveratrol glycoside irashobora kurekura lesveratrol munsi yigikorwa cya glycosidase mumira yira. Munsi ya ultraviolet, trans-reveratrol irashobora guhinduka muri Cis-isomers.
Uburyo bwo gutegura
Uburyo bwibintu bisanzwe byo gukuramo
Inzabibu, ipfundo hamwe n'ibishyimbo bikoreshwa nkibikoresho fatizo byo gukuramo no gutandukanya ubutegetsi, hanyuma uzeze. Ikoranabuhanga nyamukuru rikuramo ikoranabuhanga ririmo gukuramo kama, gukuramo alkaline no gukuramo enzyme. Uburyo bushya nka microwave-afashwa, CO2 Kureka Kureka no gukuramo ibishushanyo bya Ultrason-bikoreshwa nabyo. Intego yo kwezwa ahanini ni ugutandukanya na CIS- na Trans-isomers yo gusubira hamwe na reveratrol kuva kugaruka kwa bubi kugirango babone trans-reveratrol. Uburyo busanzwe bwo kweza burimo chromatography, Silica Gel Inkingi ya Chromatography, Thinato ya chromatografi, imikorere yinyuma ya chromatografiya, nibindi.
Uburyo bwa Synthesis
Kuva ibikubiye murireveratrolMubihingwa biri hasi cyane kandi igiciro cyo gukuramo ni kinini, gukoresha imiti, ubuhanga bwa genetique nubundi buryo kugirango ubone reveratrol byabaye uburyo bwingenzi mubikorwa byiterambere. Igitekerezo cya Perkin, Hech reaction, kandi imyifatire yahiye ni uburyo bukuze bukuze bwo guhuza ibisubizo, hamwe n'umusaruro wa 55.2%, 70%, na 35,7%. Ikoranabuhanga ryubwubatsinganiza rikoreshwa mugukemura cyangwa kunoza inzira ya biosynthesis ya resveratrol kugirango ibone imigenzo itangwa cyane; Uburyo nko gukoresha indaneSneis kugirango uhitemo imirongo ya selile ndende irashobora kongera umusaruro w'ikiruhuko kuri 1.5 ~ 3.000.
Ni izihe nyungu zaReveratrol?
Revetoatrol yabaye ubushakashatsi kubera inyungu zishoboka zubuzima. Zimwe mu nyungu zishobora kuba zirimo:
1.nting
Mu 2003, umwarimu wa kaminuza ya Harvard David Danclair maze ikipe ye yavumbuye ko abategetsi bashobora gukora acetylase kandi bongera ubuzima bw'umusemburo, bateje imbere igihe cyo kurwanya ubushakashatsi bwo kurwanya abasaza kuri resveratrol. Howitz et al. Habonetse ko reveratrol ishobora kuba umukinnyi ukomeye wamakuru acecetse amakuru arwanya 2 homolog1, arashobora kwigana igisubizo cyo kurwanya ya calorie (cr), no kwitabira amabwiriza yubuzima bwibinyabuzima. . CR ninducer ikomeye ya sirt1 kandi irashobora kongera imvugo ya sirt1 mu nzego n'ingingo nk'inkomoko, umutima, imitima, amara, imitsi n'ibinure. CR irashobora gutera impinduka za physiologiya itinda gusaza no kwagura ubuzima, nibyingenzi bishobora kongerwa na 50%. . Ubushakashatsi bwemeje ko reveratrol ishobora kwagura ubuzima bwumusemburo, nematoyo, isazi yimbuto n'amafi yo hepfo.
2.anti-ikibyimba, kurwanya kanseri
Ingabo zifite ingaruka zikomeye ku bisobanuro binyuranyije na selile zitandukanye nk'imbeba Hepatollilall Carcinoma, kanseri y'ibere, kanseri y'amabati, kanseri y'isi, na leukemia. Bamwe mu bahanga bemeje ko abajijwe bafite ingaruka zikomeye ku ndunduro ya melanoma binyuze mu buryo bwa MTT no kumeneka.
Hariho amakuru ko reveratrol ashobora kuzamura kanseri ya kanseri kandi akabuza neza ingaruka zinganda za kanseri. Ariko kugeza ubu, kubera uburyo bugoye bwo kurwanya ubutegetsi, abashakashatsi bataragera ku bwumvikane bwayo.
3. Kwigereranya no kuvura indwara z'umutima
Ubushakashatsi bwa Epidemiologique bwasanze "paradox yubufaransa" ni uko abafaransa bakoresha ibinure byinshi buri munsi, ariko abantu no gupfa kwanduza indwara z'umutima cyane birasa cyane n'ibihugu by'Uburayi. Iki kintu gishobora kuba gifitanye isano no gukoresha buri munsi vino nyinshi. , na reveratrol birashobora kuba ikintu nyamukuru gitekanye. Ubushakashatsi bwerekana ko reveratrol ishobora kugena urwego rwa Cholesterol ya Estrogen mu buryo bwa Estrogente mu mubiri w'abantu, bityo bikagabanya no guteza imbere indwara z'imitima, no guteza imbere indwara z'umutima mu mubiri w'umuntu. Ibyago byo gukomera indwara.
Inkunga ya 4.nantioxident:ReveratrolIbikorwa nka antioxydant, gufasha kurinda selile kuva kwangirika kwa okiside zatewe na radical yubusa. Ibi birashobora kugira ingaruka kubijyanye nubuzima rusange nubusaza.
6. Ubuzima bw'ubwonko: Ubushakashatsi bwarakoze uruhare rushobora kuvurwa mu gushyigikira ubuzima bw'ubwonko n'imikorere y'ubwonko, hamwe ninyigisho zimwe na rimwe zitanga umusaruro wa neuroppetective.
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Ni ubuhe buryo bwo gusabaReveratrol?
Reveveratrol ifite porogaramu zitandukanye kandi ikoreshwa mumirima itandukanye kubera inyungu zubuzima. Bimwe mubisabwa byo gusubirwamo birimo:
1. Ingendo zuzuzanya: Ubutegetsi bukunze gukoreshwa mumirire, akenshi byateguwe kubibazo byayo bya Antioxy na Kurwanya birwanya.
2. Ibicuruzwa byo mu ruhu
3. Ibiryo byimikorere n'ibinyobwa: Revevatrol yongeweho kugirango ikoreshwe mubiribwa n'ibinyobwa, ibinyobwa by'ibiryo by'ibiryo n'ibikoresho byibanda ku buzima, gutanga inyungu zubuzima.
4. Ubushakashatsi niterambere: Reveratrol akomeje kuba ibikorwa byubushakashatsi bwa siyansi, hamwe nubushakashatsi bukomeje bushakisha ibyifuzo byubuzima butandukanye ningaruka zayo ku gusaza, metabolism, no kubaho muri rusange.
Ni ubuhe buryo bwo gukora?
Mugihe resveratrol yizwe ku nyungu zubuzima, ni ngombwa gusuzuma uburyo bubi cyangwa imbogamizi zijyanye no kuyikoresha. Ibitekerezo bimwe bijyanye nibibi bya resveratrol birimo:
1. Ibinyabuzima bigarukira: Reveratrol ifite ibinyabuzima bike ugereranije, bivuze ko umubiri udashobora kugaragariza kandi ukayikoresha neza mugihe wafashwe kumunwa. Ibi birashobora guhindura imikorere yayo mugutanga ingaruka zubuzima.
2. Kubura ibipimo ngenderwaho: Ubwiza no kwibanda kunyongera byo kuruhuka birashobora gutandukana, kandi hariho kubura ibipimo ngenderwaho mugukora izi nyongera. Ibi birashobora gutuma bigora abaguzi kugirango bamenye dosage ikwiye nubwiza bwibicuruzwa.
3. Imikoranire ishobora: reveratrol irashobora gukorana nimiti cyangwa ubuzima bwubuzima. Ni ngombwa kugisha inama umwuga w'ubuzima mbere yo gukoresha ubutegetsi, cyane cyane niba ufata indi miti cyangwa ufite ibibazo byihariye byubuzima.
4. Imipaka igarukira: Mugihe ubushakashatsi bumwe bwerekanye ingaruka zizerera, hakenewe ubundi bushakashatsi kugirango dusobanukirwe neza ingaruka ndende, dosage nziza, hamwe ningaruka zijyanye ninyongera yo kuruhuka.
Nkibintu byose, ni byiza kwegera ikoreshwa ryimibano witonze kandi uyobowe numwuga wubuzima, cyane cyane niba ufite ibibazo byihariye byubuzima cyangwa bigafata indi miti.
Ibibazo bifitanye isano Urashobora Gushishikazwa:
Ninde ugomba kwirindareveratrol?
Abantu bamwe bagomba kwitonda cyangwa kwirinda gusubirwamo, cyane cyane muburyo bwo kwinjira. Nibyiza ko amatsinda akurikira azagisha inama inzobere mu buzima mbere yo gukoresha resveratrol:
1. Abagore batwite cyangwa bonsa
2. Abantu bafata amaraso yoroheje: Imbaraga zirashobora kugira imitungo yoroheje anticoagulant, abantu rero bafata imiti yoroheje yamaraso mbere yo gukoresha abahakanyi kugirango birinde imikoranire.
3. Abafite imisemburo-yoroheje: Ikaba yize ingaruka zishobora kuba kubyerekeranye n'amakuru ya Hormone, bityo abantu bafite imivugo yo mu misemburo cyangwa izo mvugo zirimo imivurungano zigomba gukoresha reveratrol no kwitonda no kugenzura ubuvuzi.
4. Abantu bafite umwijima: ubushakashatsi bumwe bwasabye ko inshuro nyinshi ziva ku butegetsi zishobora kugira ingaruka ku mwijima. Abantu bafite umwijima cyangwa abafata imiti bigira ingaruka ku mwijima bagomba gukoresha ivuye ku butegetsi no kwitonda no kugenzura ubuvuzi.
Kimwe ninyongera, ni ngombwa kugisha inama inzobere mu buzima mbere yo gukoresha ubutegetsi, cyane cyane niba ufite ibibazo byihariye byubuzima, ufata imiti, cyangwa ufite ubuzima bwiza.
Guhamuka gukora iki kuruhu?
Reveveratrol yizera ko atanga inyungu nyinshi ku ruhu, ikaba yarayinjije mu bicuruzwa. Zimwe mu ngaruka zo gusubirwamo kuruhu zishobora kubamo:
1. Kurinda Antioxident: ibikorwa by'imibavu nk'ikirere, gufasha kutesha agaciro radicals kubuntu no kugabanya imihangayiko ku ruhu. Ibi birashobora kurinda uruhu kwangirika ibidukikije, nkimirasire numwanda.
2. Anti-an-anting Producties: Resveratrol yatekerezaga ko irwanya abasaza, kuko ishobora gufasha kugabanya isura yimirongo myiza nuburyo bworoshye, kandi bifasha muri rusange ubuzima bwuruhu.
3. Ingaruka zirwanya inflammatory: Ingabo zimaze kwigwa kubushobozi bwayo bwo kurwanya induru, zishobora gufasha gutuza no gutuza uruhu, cyane cyane uruhu rwinshi cyangwa uruhu.
4.
Ni ibihe biryo biri hejuru muri resveratrol?
Ibiryo biri hejuru muri reveratrol birimo:
1. Inzabibu zitukura: Reveratrol ni nyinshi cyane muruhu rwinzabibu zitukura, bigatuma divayi itukura isoko ya reveratrol. Ariko, ni ngombwa kurya inzoga mu rugero, n'andi masoko ya reveratrol irashobora guhitamo kubatari abanywa.
2. Ibishyimbo: Ubwoko bumwe bwibishyimbo, cyane cyane uruhu rwibishyimbo, rurimo umubare wa resveratrol.
3. Ubururu: Ubururu buzwiho ingingo zabo, kandi zirimo kandi zirimo resveratrol, nubwo ziri mumafaranga mato ugereranije ninzabibu zitukura hamwe nibishyimbo.
4. Cranberries: Cranberries niyindi soko rya reseverol, zitanga ingano yoroheje.
5. Shokora yijimye: Ubwoko bumwe bwa shokora yijimye burimo gusiganwa, gutanga inzira nziza yo kwinjizamo iyi ngabo mumirire.
Nibyiza gufata reveratrol buri munsi?
Icyemezo cyo gufata urugo buri munsi kigomba gukorwa mugisha inama inzobere mu buzima, cyane cyane niba urebye inyongera yo kuruhuka. Mugihe resveratrol ifatwa nkimibereho iyo zikoreshwa muburyo busanzwe buboneka mubiribwa, umutekano ninyungu zishobora gutera abantu ku giti cye, ubuvuzi buriho, hamwe nindi miti ifatwa.
Uburozi bwuburozi bwumwijima?
Resveratrol yizwe ku ngaruka zishobora kugaragazwa numwijima, kandi mugihe muri rusange ifatwa nkumutekano iyo umaze gukoreshwa mubiryo, hari ibimenyetso byerekana ko imiserikiro yo hejuru ishobora kugira ingaruka ku mwijima. Ubushakashatsi bumwe bwerekanye ko dosiye yo hejuru ishobora kuganisha ku burozi bwumwijima mubihe bimwe.
Ni ngombwa kumenya ko ubushakashatsi kuriyi ngingo burakomeje, kandi amahirwe yo kubeshya uburozi bwumwijima burashobora gutwarwa nibintu nka dosage, igihe cyo gukoresha, nubuzima bwumuntu. Nkinyongera, ni byiza kugisha inama inzobere mu buzima mbere yo gukoresha ubutegetsi, cyane cyane niba ufite ibibazo byihariye byubuzima cyangwa bigafata indi miti ishobora kugira ingaruka kumiterere yumwijima.
Ubutegetsi bubi ni impyiko?
Hano haribimenyetso bike byerekana ko reveratrol ari mibi yimpyiko. Ariko, kimwe ninyongera, ni ngombwa kwegera ikoreshwa ryitondewe, cyane cyane niba ufite impyiko zihari cyangwa zifata imiti ishobora kugira ingaruka kumikorere yimpyiko. Nibyiza kugisha inama umunyamwuga wubuzima kugirango umenye niba inyongera yo gusiganwa ibijyanye nubuzima bwawe bwite, cyane cyane niba ufite impungenge zijyanye ningaruka zayo kubuzima bwimpyiko.
ICYO NTIBISHOBORA KUBONA NAWEreveratrol?
Mugihe usuzumye inyongera yo kuruhuka, ni ngombwa kumenya imikoranire ishobora kuba nibindi bintu. Ibitekerezo bimwe kubijyanye no kudavana na resveratrol harimo:
1. Imiti yoroheje yamaraso: Resveratrol irashobora kugira imitungo yoroheje ya anticoagulant, ni ngombwa rero gukoresha ubwitonzi mugihe ufashe reverall hamwe nimiti yoroshye yamaraso, kuko ishobora kongera ibyago byo kuva amaraso.
2. Andi Antioxident: Mugihe Antioxydants muri rusange ingirakamaro, ifata dosiye ndende yibisobanuro byinshi byinyongera icyarimwe Nibyiza kugisha inama umwuga wubuzima mbere yo guhuza reveveratrol hamwe nizindi nyongera yinyongera.
3. Imiti imwe n'imwe: Reveratrol irashobora gukorana n'imiti yihariye, harimo n'abo metabolize n'umwijima. Ni ngombwa kuganira ku mikoranire ishobora kuba ifite inzobere mu buzima, cyane niba ufata indi miti.
Nkinyongera, ni ngombwa gushaka ubuyobozi bwumwuga wubuzima bwo kumenya uburyo bukwiye bwo gukoresha resveratrol ukurikije ubuzima bwubuzima hamwe nibibazo bishobora kuba.
Nshobora gukoresha Vitamine C hamwe na resveratrol?
Nibyo, urashobora muri rusange ukoresheje vitamine C hamwe na reseverol. Mubyukuri, ubushakashatsi bwerekana ko guhuza reveratrol hamwe na vitamine C bishobora kuzamura ingaruka za Antioxident yo murwego rwibice byombi. Vitamine C ni antioxidant zizwi cyane zishobora kuzuza inyungu zishobora kuvurwa. Ariko, kimwe no guhuza inyongera, nibyiza kugisha inama inzobere mu buzima kugira ngo habeho guhuza ubuzima bwawe ndetse no kuganira ku mikoranire cyangwa ibishoboka byose.
Igihe cyohereza: Sep-09-2024
