• NikiLycopene ?
Lycopene ni karotenoide isanzwe, iboneka cyane mu mbuto n'imboga nk'inyanya. Imiterere yimiti irimo 11 ihuza inshuro ebyiri hamwe na 2 idahuza kabiri, kandi ifite ibikorwa bikomeye bya antioxydeant.
Lycopene irashobora kurinda intanga ngabo ROS, bityo igahindura umuvuduko wintanga, ikabuza hyperplasia ya prostate, kanseri ya prostate kanseri ya kanseri, kugabanya indwara zumwijima wamavuta, atherosklerozose nindwara z'umutima zifata umutima, kunoza ubudahangarwa bwabantu, no kugabanya kwangirika kwuruhu biterwa numucyo ultraviolet.
Umubiri wumuntu ntushobora guhuza lycopene yonyine, kandi ushobora kwinjizwa gusa mubiryo. Nyuma yo kwinjizwa, ibikwa cyane mu mwijima. Irashobora kuboneka muri plasma, seminal viticles, prostate nizindi ngingo.
• Ni izihe nyunguLycopeneKubitegura Gutwita Abagabo?
Nyuma yo gukora RAGE, irashobora gutera ingirabuzimafatizo kandi biganisha ku musaruro wa ROS, bityo bikagira ingaruka kumikorere yintanga. Nka antioxydants ikomeye, lycopene irashobora kuzimya ogisijeni imwe rukumbi, ikuraho ROS, kandi ikarinda lipoproteine yintanga na ADN kuba okiside. Ubushakashatsi bwerekanye ko lycopene ishobora kugabanya urwego rwakira ibicuruzwa biva mu mahanga (RAGE) mu masohoro y’abantu, bityo bikagenda neza.
Lycopene irimo byinshi mu ntangangabo z'abagabo bazima, ariko munsi y'abagabo batabyara. Ubuvuzi bwa Clinical bwerekanye ko lycopene ishobora kuzamura ubwiza bwintanga ngabo. Abagabo batabyara bafite imyaka 23 kugeza 45 basabwe gufata lycopene kumunwa kabiri kumunsi. Nyuma y'amezi atandatu, intanga zabo zibanze, ibikorwa n'imiterere byongeye kugenzurwa. Ibice bitatu bya kane byabagabo bari barahinduye cyane intanga ngabo na morphologie, kandi intanga ngabo zateye imbere cyane.
• Ni izihe nyunguLycopeneKuri Prostate Yabagabo?
1. Hyperplasia ya Prostatike
Indwara ya hyperplasia ya prostate ni indwara ikunze kugaragara ku bagabo, kandi mu myaka yashize, umubare w'abanduye wagabanutse cyane. Ibimenyetso byo mu nkari zo hasi (byihutirwa byinkari / inkari nyinshi / inkari zuzuye) ni byo bintu nyamukuru byerekana ivuriro, bigira ingaruka zikomeye ku mibereho y’abarwayi.
LycopeneIrashobora guhagarika ikwirakwizwa ry'uturemangingo twa prostate epithelia, igatera apoptose mu ngingo za prostate, igatera itumanaho hagati y’imyanya ndangagitsina kugirango irinde amacakubiri, kandi igabanye neza urwego rwibintu bitera umuriro nka interleukin IL-1, IL-6, IL-8 na necrosis yibibyimba. ibintu (TNF-α) kugirango bigire ingaruka zo kurwanya inflammatory.
Igeragezwa ry’amavuriro ryerekanye ko lycopene ishobora guteza imbere hyperplasia ya prostate hamwe n’uruhago rworoheje rwimitsi ya fibre fibre kubantu bafite umubyibuho ukabije kandi bikagabanya ibimenyetso byinkari zo hasi zumugabo. Lycopene igira ingaruka nziza zo kuvura no kunoza ibimenyetso byinkari zo hepfo yinkari zatewe na hypertrophy ya prostate na hyperplasia, ibyo bikaba bifitanye isano na antioxydeant na anti-inflammatory ingaruka za lycopene.
2. Kanseri ya prostate
Hano hari ibitabo byinshi byubuvuzi bishyigikira ibyolycopenemu mirire ya buri munsi igira uruhare runini mu gukumira kanseri ya prostate, kandi gufata lycopene bifitanye isano mbi n’ibyago bya kanseri ya prostate. Uburyo bwabwo bukekwa ko bufitanye isano no kugira ingaruka ku miterere ya gen na proteyine zifitanye isano n’ibibyimba, bikabuza ikwirakwizwa rya kanseri ya kanseri no gufatira hamwe, no kongera itumanaho hagati y’imitsi.
Ubushakashatsi ku ngaruka za lycopene ku kigero cyo kubaho kwa kanseri ya prostate ya muntu: Mu bushakashatsi bw’ubuvuzi, lycopene yakoreshejwe mu kuvura imirongo ya kanseri ya prostate DU-145 na LNCaP.
Ibisubizo byerekanye kolycopeneyagize ingaruka zikomeye zo guhagarika ikwirakwizwa rya selile DU-145, kandi ingaruka zo kubuza zagaragaye kuri 8μmol / L. Ingaruka yo kubuza lycopene kuri yo yari ifitanye isano neza nigipimo, kandi igipimo ntarengwa cyo kubuza gishobora kugera kuri 78%. Mugihe kimwe, irashobora kubuza cyane ikwirakwizwa rya LNCaP, kandi hariho isano igaragara. Igipimo ntarengwa cyo kubuza kurwego rwa 40μmol / L gishobora kugera kuri 90%.
Ibisubizo byerekana ko lycopene ishobora kubuza ikwirakwizwa rya selile ya prostate kandi bikagabanya ibyago byo kwandura kanseri ya prostate kuba kanseri.
Igihe cyo kohereza: Ugushyingo-20-2024
