Icyatsi gishya gitanga ubuziranenge Artemisia Annua Gukuramo Ifu ya Artemisinin 98%
Ibisobanuro ku bicuruzwa
Artemisinin ni ibikoresho bya farumasi byakuwe mu gihingwa cya Artemisia annua, kizwi kandi nka dihydroartemisinin. Ni imiti igabanya ubukana kandi ikoreshwa cyane mu kuvura malariya. Artemisinin igira ingaruka zikomeye zo kwica kuri Plasmodium, cyane cyane kuri gametocytes yumugore na schizonts ya Plasmodium. Artemisinin n'ibiyikomokaho byabaye umwe mu miti ikomeye yo kuvura malariya kandi ifite akamaro kanini mu kuvura malariya.
Mu myaka yashize, hamwe n’ubushakashatsi bwimbitse, artemisinin yasanze kandi ifite izindi ngaruka za farumasi, nka anti-tumor, kuvura hypertension yimpaha, anti-diyabete, uburozi bwa embryonic, anti-fungal, amabwiriza y’ubudahangarwa, virusi, anti-anti inflammatory, anti-pulmonary fibrosis, antibacterial, cardiovascular nizindi ngaruka za farumasi.
Artemisinin ni kirisiti ya acicular itagira ibara, ibora muri chloroform, acetone, Ethyl acetate na benzene, gushonga muri Ethanol, ether, gushonga gato muri peteroli ikonje, hafi ya yose idashonga mumazi. Kubera amatsinda yihariye ya peroxy, ntabwo ihindagurika cyane kandi irashobora kwangirika nubushuhe, ubushyuhe no kugabanya ibintu.
COA :
Izina ry'ibicuruzwa: | Artemisinin | Itariki y'Ikizamini: | 2024-05-16 |
Icyiciro Oya.: | NG24070501 | Itariki yo gukora: | 2024-05-15 |
Umubare: | 300kg | Itariki izarangiriraho: | 2026-05-14 |
INGINGO | STANDARD | IBISUBIZO |
Kugaragara | Cyera Powder | Hindura |
Impumuro | Ibiranga | Hindura |
Biryohe | Ibiranga | Hindura |
Suzuma | ≥98.0% | 98.89% |
Ibirimo ivu | ≤0.2% | 0.15% |
Ibyuma biremereye | ≤10ppm | Hindura |
As | ≤0.2ppm | <0.2 ppm |
Pb | ≤0.2ppm | <0.2 ppm |
Cd | ≤0.1ppm | <0.1 ppm |
Hg | ≤0.1ppm | <0.1 ppm |
Umubare wuzuye | , 000 1.000 CFU / g | <150 CFU / g |
Umubumbe & Umusemburo | ≤50 CFU / g | <10 CFU / g |
E. Kol | MP10 MPN / g | <10 MPN / g |
Salmonella | Ibibi | Ntibimenyekana |
Staphylococcus Aureus | Ibibi | Ntibimenyekana |
Umwanzuro | Hindura kubisobanuro bisabwa. | |
Ububiko | Ubike ahantu hakonje, humye kandi uhumeka. | |
Ubuzima bwa Shelf | Imyaka ibiri niba ifunze kandi ikabikwa kure yizuba ryinshi nubushuhe. |
Imikorere:
Artemisinin ni imiti igabanya ubukana ko:
1. Kwica Plasmodium: Artemisinin igira ingaruka zikomeye zo kwica kuri Plasmodium, cyane cyane kuri gametocytes yumugore na schizonts ya Plasmodium.
2. Kuraho vuba ibimenyetso: Artemisinin irashobora kugabanya vuba ibimenyetso nkumuriro, gukonja, kubabara umutwe nibindi bimenyetso kubarwayi ba malariya. Numuti wihuse kandi mwiza urwanya malariya.
3. Irinde ko malariya itazongera kubaho: Artemisinin irashobora kandi gukoreshwa kugirango wirinde ko malariya itazongera kubaho, cyane cyane mu turere tumwe na tumwe twanduye malariya. Gukoresha artemisinin birashobora gufasha kwirinda ikwirakwizwa rya malariya.
Gusaba:
Artemisinin niwo muti ufite akamaro kanini mu kuvura malariya, kandi ubuvuzi bwa artemisinin bushingiye ku buvuzi nabwo ni uburyo bwiza kandi bw’ingenzi bwo kuvura malariya muri iki gihe. Nyamara, hamwe n’ubushakashatsi bwimbitse mu myaka yashize, havumbuwe izindi ngaruka nyinshi za artemisinin, nko kurwanya ibibyimba, kuvura hypertension y’impyiko, kurwanya diyabete, uburozi bw’inda, antifungali, kugenzura indwara n’ibindi.
1. Kurwanya malariya
Malariya ni indwara yanduza udukoko, indwara yandura iterwa no kurumwa na parasite yanduye parasite, ishobora gutera umwijima no kwaguka nyuma y’ibitero byinshi igihe kirekire, kandi iherekejwe no kubura amaraso nibindi bimenyetso. Artemisinin yagize uruhare runini mu kugera ku rwego runaka rwo kuvura malariya.
2. Kurwanya ikibyimba
Ubushakashatsi bwa vitro bwerekana ko igipimo runaka cya artemisinine gishobora gutera apoptose ya kanseri yumwijima, kanseri yamabere, kanseri yinkondo y'umura nizindi selile, kandi bikabuza cyane gukura kwa kanseri.
3. Kuvura hypertension yimpyisi
Indwara ya hypertension (PAH) ni indwara ya pathophysiologique irangwa no kuvugurura imiyoboro y'amaraso no kuzamura umuvuduko w'amaraso ku gipimo runaka, gishobora kuba ingorabahizi cyangwa syndrome. Artemisinin ikoreshwa mu kuvura umuvuduko ukabije w'amaraso: igabanya umuvuduko w'amaraso kandi ikanagaragaza ibimenyetso ku barwayi barwaye PAH mu kwagura imiyoboro y'amaraso. Artemisinin igira ingaruka zo kurwanya inflammatory, artemisinin hamwe nintungamubiri zayo birashobora guhagarika ibintu bitandukanye bitera umuriro, kandi birashobora kubuza umusaruro wa aside nitide nabunzi batera umuriro. Artemisinin irashobora kubuza ikwirakwizwa ry'uturemangingo twa endoteliyale y'amaraso hamwe na selile yoroshye y'imitsi, bigira uruhare runini mu kuvura PAH. Artemisinin irashobora guhagarika ibikorwa bya matrix metalloproteinase bityo ikabuza kuvugurura imitsi yimitsi. Artemisinin irashobora guhagarika imvugo ya cytokine ijyanye na PAH, kandi ikarushaho kunoza ingaruka zo kuvugurura imitsi ya artemisinin.
4. Amategeko agenga ubudahangarwa
Byagaragaye ko igipimo cya artemisinin n'ibiyikomokaho bishobora kubuza T lymphocyte mitogen T idateye cytotoxicity, bityo bigatuma ikwirakwizwa rya lymphocytes yimbeba.
5. Kurwanya ibihumyo
Igikorwa cya antifungal ya artemisinin nayo ituma artemisinin yerekana ibikorwa bimwe na bimwe bya antibacterial. Ubushakashatsi bwemeje ko ifu y’ibisigazwa bya artemisinin hamwe n’amazi y’amazi yagize ibikorwa bikomeye bya antibacterial anti antacracis, Staphylococcus epidermidis, Coccus catarrhus na Bacillus diphtheriae, ndetse ikagira n'ibikorwa bimwe na bimwe bya antibacterial kurwanya Bacillus igituntu, Bacillus aeruginosa, Staphylocoa.
6. Kurwanya diyabete
Artemisinin irashobora kandi gukiza abantu barwaye diyabete. Abashakashatsi bo mu kigo cya CeMM gishinzwe ubuvuzi bwa Molecular mu Ishuri Rikuru ry’Ubumenyi rya Otirishiya hamwe n’ibindi bigo basanze artemisinin ishobora gutuma selile ya alpha ikora glucagon "ihinduka" mu ngirabuzimafatizo za beta zitanga insuline. Artemisinin ihuza poroteyine yitwa gephyrin. Gephyrin ikora reseptor ya GABA, inzira nyamukuru yo gutangaza ibimenyetso. Ibikurikira, reaction nyinshi yibinyabuzima irahinduka, biganisha ku gukora insuline.
7. Kuvura syndrome ya polycystic ovary
Ubushakashatsi bwerekanye ko ibikomoka kuri artemisinin bishobora kuvura PCOS no gusobanura uburyo bujyanye nabyo, bigatanga igitekerezo gishya cyo kuvura amavuriro ya PCOS n'indwara ziterwa no kuzamuka kwa androgene.