Uruganda rushya rutanga Topotecan Hydrochloride Yujuje ubuziranenge 99% Ifu ya Topotecan Hydrochloride
Ibisobanuro ku bicuruzwa
Topotecan Hydrochloride ni imiti ya chimiotherapie ikoreshwa cyane cyane mu kuvura ubwoko bumwe na bumwe bwa kanseri. Nuburyo bwa hydrochloride ya topotecan, inhibitor ya topoisomerase ikora cyane cyane muguhagarika ibikorwa bya ADN topoisomerase I.
Inyandiko:
Iyo ukoresheje Topotecan, abarwayi bagomba kuyoborwa na muganga, cyane cyane kubarwayi bafite umwijima nimpyiko cyangwa ibindi bibazo byubuzima. Kwipimisha amaraso buri gihe birasabwa mugihe cyo kuvura kugirango harebwe ingaruka zishobora kubaho.
Mu gusoza, Topotecan Hydrochloride ni umuti wingenzi wa anticancer, ukoreshwa cyane mu kuvura kanseri yintanga na kanseri ntoya yibihaha, kandi ufite agaciro gakomeye mubuvuzi.
COA
| Ibintu | Ibisobanuro | Ibisubizo |
| Kugaragara | Ifu yera cyangwa yera | Ifu yera |
| Kumenyekanisha HPLC | Bihuye nibisobanuro ibintu nyamukuru impinga yo kugumana igihe | Guhuza |
| Kuzenguruka byihariye | +20.0 。- + 22.0。 | +21。 |
| Ibyuma biremereye | ≤ 10ppm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Gutakaza kumisha | ≤ 1.0% | 0,25% |
| Kuyobora | ≤3ppm | Guhuza |
| Arsenic | ≤1ppm | Guhuza |
| Cadmium | ≤1ppm | Guhuza |
| Mercure | ≤0. 1ppm | Guhuza |
| Ingingo yo gushonga | 250.0℃~ 265.0℃ | 254.7 ~ 255.8℃ |
| Ibisigisigi byo gutwikwa | ≤0. 1% | 0.03% |
| Hydrazine | ≤2ppm | Guhuza |
| Ubucucike bwinshi | / | 0.21g / ml |
| Ubucucike | / | 0.45g / ml |
| Suzuma（Topotecan Hydrochloride） | 99.0% ~ 101.0% | 99.65% |
| Indege zose zirabaze | 0001000CFU / g | <2CFU / g |
| Ibishushanyo & Umusemburo | ≤100CFU / g | <2CFU / g |
| E.coli | Ibibi | Ibibi |
| Salmonella | Ibibi | Ibibi |
| Ububiko | Ubike ahantu hakonje & humye, gumana urumuri rukomeye. | |
| Umwanzuro | Yujuje ibyangombwa | |
Imikorere
Topotecan Hydrochloride ni imiti ya chimiotherapie ikoreshwa cyane cyane mu kuvura ubwoko bumwe na bumwe bwa kanseri. Nibikoresho bya topoisomerase hamwe nuburyo bukurikira bwibikorwa nibikorwa:
Igikorwa:
1. Kubuza Topisomerase.
2.Ibikorwa bya antitumor: Topotecan ikoreshwa cyane mu kuvura kanseri yintanga, kanseri ntoya yibihaha hamwe nubwoko bumwe na bumwe bwa lymphoma. Irashobora gukoreshwa nkumurongo wambere cyangwa nkumurongo wa kabiri nyuma yubuvuzi bwananiranye.
3.Hamagara umuzenguruko wihariye: Ingaruka ya Topotecan kumuzunguruko igaragara cyane cyane mugice cya S na G2, bigatuma igira ingaruka zikomeye zo kwica kanseri ya kanseri mugihe cyihariye cyo gukwirakwiza selile.
4.Ubuvuzi: Topotecan irashobora gukoreshwa hamwe nindi miti ya chimiotherapie kugirango igabanye ingaruka zo kurwanya ibibyimba no kunoza uburyo bwo kuvura umurwayi.
5.Kuraho ibimenyetso: Rimwe na rimwe, gukoresha Topotecan birashobora gufasha kugabanya ibimenyetso biterwa na kanseri no kuzamura imibereho yumurwayi.
Inyandiko:
Topotecan irashobora gutera ingaruka zimwe, zirimo ariko ntizigarukira gusa ku isesemi, kuruka, umunaniro, leukopenia, nibindi. Iyo ukoresheje uyu muti, abarwayi bakeneye gukurikiranwa no gucungwa bayobowe na muganga.
Mu gusoza, Topotecan Hydrochloride ni imiti igabanya ubukana ikora antitumor cyane cyane binyuze mu kubuza ADN topoisomerase I.
Gusaba
Topotecan Hydrochloride ni imiti ya chimiotherapie ikoreshwa cyane cyane mu kuvura ubwoko bumwe na bumwe bwa kanseri. Ibikurikira nuburyo bukoreshwa byingenzi:
1. Kanseri y'intanga: Topotecan isanzwe ikoreshwa mu kuvura kanseri yintanga ikunze kugaragara, cyane cyane kubarwayi nyuma yandi miti (nka chimiotherapie ishingiye kuri platine) yananiwe. Irashobora gukoreshwa nkumukozi umwe cyangwa ifatanije nibindi biyobyabwenge.
Kanseri y'ibihaha ntoya: Uyu muti urakoreshwa no mu kuvura kanseri y'ibihaha ntoya, ubusanzwe nk'uburyo bwa kabiri bwo kuvura, cyane cyane iyo indwara isubiye nyuma ya chimiotherapie ya mbere.
3.Indi Kanseri.
4. Ibigeragezo: Topotecan nayo irasuzumwa mugupima kwa kanseri zitandukanye kugirango yige imikorere yayo numutekano muburyo butandukanye bwo kuvura.
5.Ubuvuzi: Rimwe na rimwe, Topotecan irashobora gukoreshwa hamwe nindi miti ya chimiotherapie cyangwa imiti igamije kuvura kugirango yongere imbaraga zo kuvura.
Inyandiko:
Iyo ukoresheje Topotecan, abarwayi bagomba kuyoborwa na muganga, cyane cyane kubarwayi bafite umwijima nimpyiko cyangwa ibindi bibazo byubuzima. Kwipimisha amaraso buri gihe birasabwa mugihe cyo kuvura kugirango harebwe ingaruka zishobora kubaho.
Mu gusoza, Topotecan Hydrochloride ifite akamaro gakomeye mu kuvura kanseri, cyane cyane mu micungire ya kanseri yintanga ngore na kanseri y'ibihaha nto.
Gupakira & Gutanga
