Uruganda rushya rutanga Rimonabant Yujuje ubuziranenge 99% Ifu ya Rimonabant
Ibisobanuro ku bicuruzwa
Rimonabant ni imiti ikoreshwa cyane cyane mu kuvura umubyibuho ukabije n'indwara ziterwa na metabolike. Ibikurikira nintangiriro ya Rimonabant:
1. Urwego rwibiyobyabwenge
Rimonabant ni urumogi rwatoranijwe rwo mu bwoko bwa 1 (CB1) reseptor antagonist kandi ni mubyiciro bishya byibiyobyabwenge birwanya umubyibuho ukabije.
2. Intego nyamukuru
Gutakaza ibiro: Rimonabant irategurwa kugirango ifashe abarwayi bafite umubyibuho ukabije guta ibiro, cyane cyane abafite syndrome de metabolike.
Itezimbere Ubuzima bwa Metabolic: Usibye kugabanya ibiro, Rimonabant yizera kandi ko izamura ibibazo bya metabolike bijyanye n'umubyibuho ukabije, nk'isukari nyinshi mu maraso, cholesterol nyinshi n'umuvuduko ukabije w'amaraso.
Mu gusoza, Rimonabant ni ikiyobyabwenge cyumubyibuho ukabije hamwe na syndrome de metabolike hamwe nuburyo bwihariye bwibikorwa ndetse ningaruka zishobora kubaho, ariko ikoreshwa ryayo ni rito cyane kubera ingaruka ziterwa n'ingaruka. Igomba gukoreshwa iyobowe na muganga kandi ikurikiranwa neza.
COA
| Ibintu | Ibisobanuro | Ibisubizo |
| Kugaragara | Hanze-ifu yera cyangwa yera | Ifu yera |
| Kumenyekanisha HPLC | Bihuye nibisobanuro ibintu nyamukuru impinga yo kugumana igihe | Guhuza |
| Kuzenguruka byihariye | + 20.0。 + 22.0。 | +21。 |
| Ibyuma biremereye | ≤ 10ppm | <10ppm |
| PH | 7.58.5 | 8.0 |
| Gutakaza kumisha | ≤ 1.0% | 0,25% |
| Kuyobora | ≤3ppm | Guhuza |
| Arsenic | ≤1ppm | Guhuza |
| Cadmium | ≤1ppm | Guhuza |
| Mercure | ≤0. 1ppm | Guhuza |
| Ingingo yo gushonga | 250.0℃~ 265.0℃ | 254.7 ~ 255.8℃ |
| Ibisigisigi byo gutwikwa | ≤0. 1% | 0.03% |
| Hydrazine | ≤2ppm | Guhuza |
| Ubucucike bwinshi | / | 0.21g / ml |
| Ubucucike | / | 0.45g / ml |
| Suzuma （Rimonabant） | 99.0% ~ 101.0% | 99.55% |
| Indege zose zirabaze | 0001000CFU / g | <2CFU / g |
| Ibishushanyo & Umusemburo | ≤100CFU / g | <2CFU / g |
| E.coli | Ibibi | Ibibi |
| Salmonella | Ibibi | Ibibi |
| Ububiko | Ubike ahantu hakonje & humye, gumana urumuri rukomeye. | |
| Umwanzuro | Yujuje ibyangombwa | |
Imikorere
Rimonabant ni umuti ukoreshwa cyane cyane mu gucunga ibiro no kuvura syndrome de metabolike ijyanye n'umubyibuho ukabije. Ibikurikira nintangiriro yimikorere ya Rimonabant:
1. Kurwanya ubushake bwo kurya
Rimonabant ni urumogi rwatoranijwe rwa 1 (CB1) rwakira antagonist ifasha gucunga ibiro muguhagarika ibikorwa byakira urumogi, kugabanya ubushake bwo kurya.
2. Kugabanya ibiro
Rimonabant ikoreshwa mu gufasha abarwayi bafite umubyibuho ukabije guta ibiro, cyane cyane abafite syndrome de metabolike (nk'umuvuduko ukabije w'amaraso, isukari nyinshi mu maraso, na cholesterol nyinshi).
3. Kunoza ibipimo bya metabolike
Gukoresha Rimonabant birashobora kunoza ibimenyetso bifitanye isano n'umubyibuho ukabije, urugero nko kugabanya ibinure byumubiri, kunoza insuline, no kugabanya isukari mu maraso.
4. Ingaruka ku buzima bwo mu mutwe
Ubushakashatsi bumwe bwerekana ko rimonabant ishobora kugira ingaruka nziza mu kuzamura ubuzima bwo mu mutwe, cyane cyane mu kugabanya ibimenyetso byo kwiheba bijyana n'umubyibuho ukabije.
5. Ingaruka Zuruhande
Nubwo rimonabant yerekanye ubushobozi mu gucunga ibiro, imikoreshereze yayo nayo ifitanye isano n'ingaruka zimwe na zimwe, nko guhangayika, kwiheba, isesemi no kubabara umutwe. Kubera iyo mpamvu, gukoresha rimonabant byarabujijwe cyangwa bivanwa mu bihugu byinshi.
Muri make, umurimo wingenzi wa Rimonabant nugufasha abarwayi bafite umubyibuho ukabije kugabanya ibiro muguhashya ubushake no kunoza ibipimo bya metabolike. Ariko, kubera ingaruka zabyo, igomba gukoreshwa ubwitonzi kandi iyobowe na muganga.
Gusaba
Ikoreshwa rya Rimonabant ryibanze cyane cyane mubice bikurikira:
1. Kuvura umubyibuho ukabije:
Rimonabant yabanje gukorwa kugirango ivure umubyibuho ukabije, cyane cyane ku barwayi bafite ibiro byinshi kandi bafite syndrome de metabolike (nk'isukari nyinshi mu maraso, lipide nyinshi n'umuvuduko ukabije w'amaraso). Ifasha abarwayi guta ibiro mugukumira ubushake bwo kurya no guteza imbere metabolism.
2. Indwara ya metabolike:
Rimonabant iri kwigwa kugirango itezimbere ibimenyetso bifitanye isano na syndrome de metabolike, ifasha kugabanya ibiro byumubiri, kunoza insuline no kugabanya urugero rwa lipide yamaraso.
3. Gucunga diyabete:
Mu bushakashatsi bumwe na bumwe, ribonabant yerekanye inyungu zishobora kuba ku bantu barwaye diyabete yo mu bwoko bwa 2, bikaba bishoboka ko ifasha kugenzura urugero rw'isukari mu maraso mu kunoza imiterere ya metabolike no gucunga ibiro.
4. Ubuzima bw'umutima n'imitsi:
Bitewe n'ingaruka zabyo ku buzima bwa metabolike, Rimonabant nayo irimo kwigwa hagamijwe kuzamura ubuzima bw'umutima n'imitsi no kugabanya ibyago byo kurwara umutima.
Inyandiko
Nubwo rimonabant yerekanye ubushobozi mu kuvura umubyibuho ukabije na syndrome de metabolike, icyemezo cy’isoko cyakuweho mu bihugu byinshi kubera ingaruka zacyo zijyanye n'ubuzima bwo mu mutwe, nko kwiheba no guhangayika. Kubwibyo, rimonabant igomba gukoreshwa ubwitonzi kandi igakurikiza ubuyobozi bwa muganga.
Muri make, uburyo nyamukuru bwa rimonabant ni ukuvura umubyibuho ukabije na syndrome de metabolike, ariko ikoreshwa ryayo ni rito kubera ibibazo byumutekano.
Gupakira & Gutanga
