Metformin Yera Yuzuye CAS 657-24-9 Uruganda rukora Metformin
ibisobanuro ku bicuruzwa
Metformin: Umuti ukomeye wo kuvura diyabete
1. Metformin ni iki?
Biguanide iboneka mu byatsi by'ihene (Galega Officinalis), igihingwa kimaze imyaka amagana gikoreshwa mu buvuzi bwa rubanda. Igikorwa cya farumasi yikimera ubwacyo giterwa nihene (Isoamylene guanidine). Phenformin, Buformin, na metformin byose bihujwe na chimique kandi bigizwe na molekile ebyiri za guanidine. Metformin ni imiti yo mu kanwa ikoreshwa cyane mu kuvura diyabete yo mu bwoko bwa 2. Ni mubyiciro byibiyobyabwenge byitwa biguanide kandi bifatwa nkumuti wambere wo kuvura diyabete.
2.Ni gute metformin ikora?
Igikorwa nyamukuru cya Metformin nukugabanya isukari ikorwa numwijima no gutuma ingirabuzimafatizo z'umubiri zumva insuline. Igabanya neza isukari mu maraso kandi ifasha kugenzura uko umubiri wakira insuline.
Metformin igenga isukari mu maraso cyane cyane mu guhagarika isukari y'umwijima. Metformin ahanini yishingikiriza ku bwikorezi bwa cationic transport 1 (OCT 1) kugirango yinjire muri hepatocytes, hanyuma ibuza igice igice cyimyanya myanya yubuhumekero ya mitochondial 1, bigatuma ATP igabanuka no kwiyongera kurwego rwa AMP. Twese tuzi ko kugabanuka kwa ATP no kwiyongera kwa AMP mu ngirabuzimafatizo bizahagarika gluconeogenezi kandi bigabanye ihinduka rya glycerol na glucose.
Umubare wiyongereye wa AMP / ATP uterwa na metformin unakora inzira ya signal ya AMPK yerekana inzira, ibuza synthesis ibinure kandi ikongerera umubiri insuline.
3.Ni izihe nyungu za metformin?
Metformin itanga inyungu nyinshi kubantu barwaye diyabete:
1) Kugenzura isukari mu maraso: Mugabanye umusaruro wisukari mwumwijima no kunoza insuline, metformin ifasha kugenzura isukari yamaraso no kubarinda kujya hejuru cyangwa hasi cyane.
2) Gucunga ibiro: Ubusanzwe Metformin itera kugabanuka kurwego ruto kubantu barwaye diyabete. Irabikora mukugabanya ubushake bwo kurya, kongera ibyiyumvo byuzuye, no gufasha kwishora mububiko bwa glucose nibinure byingufu.
3) Kurinda umutima-mitsi: Ubushakashatsi bwerekana ko metformine ishobora kugabanya ibyago byindwara zifata umutima, nkindwara z'umutima na stroke, kubantu barwaye diyabete.
4) Indwara ya polycystic ovary syndrome (PCOS): Usibye kuvura diyabete, metformin ikoreshwa mu kuvura PCOS, indwara ya hormone yibasira abagore. Ifasha kugenga ukwezi, kugabanya kurwanya insuline, no gufasha muburumbuke.
4.Ni hehe metformin ishobora gukoreshwa?
Metformin ikoreshwa cyane mu kuvura diyabete yo mu bwoko bwa 2. Irashobora gukoreshwa wenyine cyangwa ifatanije nindi miti igabanya ubukana bwo mu kanwa cyangwa ifatanije nubuvuzi bwa insuline, bitewe nibyifuzo bya buri muntu. Metformin yerekanwa kugirango ikoreshwe kubantu bashya basuzumwe no mubantu bafite igihe kirekire cyo kurwanya diyabete. Muri make, metformin numuti ukomeye ukoreshwa cyane mukuvura diyabete yo mu bwoko bwa 2 na PCOS. Ifite inyungu nko kugenzura isukari mu maraso, gucunga ibiro, kurinda umutima n'imitsi, no kugabanya ibimenyetso bya PCOS. Bitewe nuburyo bukoreshwa kandi bukoreshwa cyane, metformin yabaye igikoresho cyingenzi mugufasha abantu kubaho neza mugihe bacunga neza imiterere yabo.
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Newgreen ni uruganda ruyoboye mubyongeweho ibiryo, rwashinzwe mu 1996, rufite uburambe bwimyaka 23 yo kohereza hanze. Hamwe n’ikoranabuhanga ryo mu rwego rwa mbere n’amahugurwa yigenga yigenga, isosiyete yafashije iterambere ry’ubukungu bw’ibihugu byinshi. Uyu munsi, Newgreen yishimiye kwerekana udushya twayo - ubwoko bushya bwinyongera bwibiryo bukoresha ikoranabuhanga rihanitse mu kuzamura ubwiza bwibiribwa.
Kuri Newgreen, guhanga udushya nimbaraga zitera ibyo dukora byose. Itsinda ryinzobere ryacu rihora riharanira iterambere ryibicuruzwa bishya kandi binonosoye kugirango tunoze ubuziranenge bwibiribwa mugihe tubungabunga umutekano nubuzima. Twizera ko guhanga udushya bishobora kudufasha gutsinda imbogamizi z’isi yihuta cyane muri iki gihe no kuzamura imibereho y’abantu ku isi. Urwego rushya rwinyongera rwijejwe kuzuza amahame yo mu rwego rwo hejuru mpuzamahanga, ruha abakiriya amahoro yo mumutima.Twihatira kubaka ubucuruzi burambye kandi bwunguka butazana iterambere gusa kubakozi bacu ndetse nabanyamigabane, ahubwo binagira uruhare mwisi nziza kuri bose.
Newgreen yishimiye kwerekana udushya tw’ikoranabuhanga rigezweho - umurongo mushya w’inyongeramusaruro uzamura ireme ry’ibiribwa ku isi. Isosiyete imaze igihe kinini yiyemeje guhanga udushya, ubunyangamugayo, gutsindira inyungu, no gukorera ubuzima bw’abantu, kandi ni umufatanyabikorwa wizewe mu nganda z’ibiribwa. Urebye ahazaza, twishimiye ibishoboka biranga ikoranabuhanga kandi twizera ko itsinda ryacu ryinzobere ryitondewe rizakomeza guha abakiriya bacu ibicuruzwa na serivisi bigezweho.
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