Pimecrolimus Newgreen Supply High Quality APIs 99% Pimecrolimus Powder
Product Description
Pimecrolimus is a topical immunomodulator, mainly used to treat atopic dermatitis (eczema). It belongs to the class of calmodulin-dependent protein phosphatase inhibitors, which can reduce the inflammatory response of the skin by inhibiting the activation of T cells and the release of inflammatory mediators.
Main Mechanics
l Immunomodulation:
Pimecrolimus reduces inflammation and itching of the skin by inhibiting the activation of T cells and other immune cells and reducing the release of inflammatory mediators.
l Local effect:
As a topical medication, Pimecrolimus acts directly on the affected area of skin, reducing the risk of systemic side effects.
Indications
l Atopic dermatitis:
For the treatment of mild to moderate atopic dermatitis, especially in patients who have not responded adequately to conventional treatments such as steroids.
l Other skin diseases:
In certain cases, Pimecrolimus may also be used for other types of skin inflammation.
COA
Items | Specifications | Results |
Appearance | White powder | Complies |
Order | Characteristic | Complies |
Assay | ≥99.0% | 99.8% |
Tasted | Characteristic | Complies |
Loss on Drying | 4-7(%) | 4.12% |
Total Ash | 8% Max | 4.85% |
Heavy Metal | ≤10(ppm) | Complies |
Arsenic(As) | 0.5ppm Max | Complies |
Lead(Pb) | 1ppm Max | Complies |
Mercury(Hg) | 0.1ppm Max | Complies |
Total Plate Count | 10000cfu/g Max. | 100cfu/g |
Yeast & Mould | 100cfu/g Max. | >20cfu/g |
Salmonella | Negative | Complies |
E.Coli. | Negative | Complies |
Staphylococcus | Negative | Complies |
Conclusion | Qualified | |
Storage | Store in a well-closed place with constant low temperature and no direct sun light. | |
Shelf life | 2 years when properly stored |
Side Effect
Pimecrolimus is generally well tolerated, but some side effects may occur, including:
Local reactions: such as burning, itching, redness, swelling or dryness.
Risk of infection: Due to immunomodulatory effects, the risk of local infection may be increased.
Allergic Reactions: In rare cases, allergic reactions may occur.
Notes
Directions: Use as directed by your physician, usually on clean skin.
Avoid sun exposure: When using Pimecrolimus, avoid direct sunlight and use sun protection measures if necessary.
Long-term use: Long-term use requires regular evaluation of efficacy and side effects.