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Mafotokozedwe Akatundu
Ticagrelor ndi mankhwala a antiplatelet, a P2Y12 receptor antagonist, omwe amagwiritsidwa ntchito makamaka pofuna kupewa zochitika zamtima, makamaka kwa odwala omwe ali ndi matenda oopsa kwambiri (ACS). Amachepetsa chiopsezo cha thrombosis poletsa kuphatikizika kwa mapulateleti.
Main Mechanics
Kuletsa kuphatikizika kwa mapulateleti:
Ticagrelor mosinthika amamangiriza ku cholandilira cha P2Y12 pamtunda wa platelet, kuletsa kutsegulira kwa mapulateleti ndi kuphatikizika komwe kumachitika chifukwa cha adenosine diphosphate (ADP), motero kumachepetsa mapangidwe a thrombus.
Zizindikiro
Ticagrelor imagwiritsidwa ntchito makamaka pazifukwa izi:
Acute Coronary Syndrome:Kuphatikizapo odwala ndi wosakhazikika angina ndi m`mnyewa wamtima infarction, kawirikawiri ntchito osakaniza aspirin kuchepetsa chiopsezo cha mtima zochitika.
Kupewa kwachiwiri kwa zochitika zamtima:Kwa odwala omwe kale anali ndi zochitika zamtima kuti ateteze wina.
COA
Zinthu | Zofotokozera | Zotsatira |
Maonekedwe | White ufa | Zimagwirizana |
Order | Khalidwe | Zimagwirizana |
Kuyesa | ≥99.0% | 99.8% |
Kulawa | Khalidwe | Zimagwirizana |
Kutaya pa Kuyanika | 4-7(%) | 4.12% |
Zonse Ash | 8% Max | 4.85% |
Chitsulo Cholemera | ≤10(ppm) | Zimagwirizana |
Arsenic (As) | 0.5ppm Max | Zimagwirizana |
Kutsogolera (Pb) | 1 ppm pa | Zimagwirizana |
Mercury (Hg) | 0.1ppm Max | Zimagwirizana |
Total Plate Count | 10000cfu/g Max. | 100cfu/g |
Yisiti & Mold | 100cfu/g Max. | >20cfu/g |
Salmonella | Zoipa | Zimagwirizana |
E.Coli. | Zoipa | Zimagwirizana |
Staphylococcus | Zoipa | Zimagwirizana |
Mapeto | Woyenerera | |
Kusungirako | Sungani pamalo otsekedwa bwino ndi kutentha pang'ono nthawi zonse komanso popanda kuwala kwa dzuwa. | |
Alumali moyo | 2 years atasungidwa bwino |
Mbali Zotsatira
Ticagrelor kawirikawiri amalekerera bwino, koma zotsatira zina zikhoza kuchitika, kuphatikizapo:
Kutuluka Magazi:Zotsatira zofala kwambiri, zomwe zingayambitse kutulutsa magazi pang'ono kapena koopsa.
Kuvuta kupuma:Odwala ena amavutika kupuma kapena kutsokomola.
Zomwe zimachitika m'mimba:monga nseru, kupweteka m'mimba kapena kusadya bwino.
Zolemba
Kuopsa kwa Magazi:Kuopsa kwa magazi kuyenera kuyang'aniridwa nthawi zonse mukamagwiritsa ntchito Ticagrelor, makamaka pamene mukugwiritsidwa ntchito limodzi ndi mankhwala ena oletsa magazi.
Ntchito ya Hepatic:Gwiritsani ntchito mosamala odwala omwe ali ndi vuto la chiwindi; Kusintha kwa mlingo kungakhale kofunikira.
Kuyanjana ndi Mankhwala:Ticagrelor akhoza kuyanjana ndi mankhwala ena. Muyenera kuuza dokotala za mankhwala onse omwe mukumwa musanagwiritse ntchito.