Terbinafine Hydrochloride High Purity API Zinthu CAS 78628-80-5
Mafotokozedwe Akatundu
Terbinafine Hydrochloridendi antifungal mankhwala omwe amagwiritsidwa ntchito pochiza matenda osiyanasiyana. Nthawi zambiri amakhala ngati mapiritsi kapena zonona. terbinafine hydrochloride ndi mankhwala othandiza antifungal omwe amagwiritsidwa ntchito pochiza matenda osiyanasiyana a mafangasi. Kaya akuthana ndi matenda a phazi kapena mafangasi a misomali, mankhwalawa amagwira ntchito polepheretsa kupanga ergosterol ndipo amapereka njira zapakamwa komanso zam'kamwa kuti zikhale zosavuta komanso zogwira mtima.
COA
| ZINTHU | ZOYENERA | ZOTSATIRA ZAKE |
| Kuyesa | 99% | Zimagwirizana |
| Mtundu | White ufa | Zimagwirizana |
| Kununkhira | Palibe fungo lapadera | Zimagwirizana |
| Tinthu kukula | 100% yadutsa 80mesh | Zimagwirizana |
| Kutaya pakuyanika | ≤5.0% | 2.35% |
| Zotsalira | ≤1.0% | Zimagwirizana |
| Chitsulo cholemera | ≤10.0ppm | 7 ppm |
| As | ≤2.0ppm | Zimagwirizana |
| Pb | ≤2.0ppm | Zimagwirizana |
| Zotsalira za mankhwala | Zoipa | Zoipa |
| Chiwerengero chonse cha mbale | ≤100cfu/g | Zimagwirizana |
| Yisiti & Mold | ≤100cfu/g | Zimagwirizana |
| E.Coli | Zoipa | Zoipa |
| Salmonella | Zoipa | Zoipa |
| Mapeto | Gwirizanani ndi Specification | |
| Kusungirako | Kusungidwa Pamalo Ozizira & Owuma, Khalani Kutali Ndi Kuwala Kwamphamvu Ndi Kutentha | |
| Alumali moyo | 2 years atasungidwa bwino | |
Ntchito
1.Terbinafine hydrochloride ndi mankhwala a allyla antifungal. Ili ndi lipophilic kwambiri ndipo imakonda kudziunjikira pakhungu, misomali, ndi minofu yamafuta.
2.Terbinafine · HCl membala wa allyl class of antifungals, wapezeka kuti ndi inhibitor yeniyeni ya ergosterol synthesis kudzera mu squalene epoxidase inhibition. Squalene epoxidase ndi puloteni yomwe imatulutsidwa ndi bowa wa dermatophyte kuti iwononge squalene, yomwe imasokoneza ntchito ya nembanemba ya ma cell ndi kaphatikizidwe ka khoma.
3.Terbinafine hydrochloride imakhala ndi fungicidal pakhungu bowa komanso inhibitory effect pa Candida albicans. Ndizoyenera pakhungu ndi misomali matenda omwe amayamba chifukwa cha bowa wowoneka bwino, monga zipere, zipere, zipere, zipere kumapazi, mphutsi ya msomali ndi Candida albicans matenda akhungu omwe amayamba chifukwa cha Trichophyton rubrum, Microsporum canis. ndi Flocculus epidermidis.
Kugwiritsa ntchito
Terbinafine hydrochloride ndi ufa woyera wa crystalline womwe umasungunuka momasuka mu methan ndi dichlorome, sungunuka mu Mowa, ndi kusungunuka pang'ono m'madzi. Monga ma allylamines ena, terbinafine imalepheretsa kaphatikizidwe ka ergosterol mwa kuletsa squalene epoxidase,
enzyme yomwe ili gawo la fungal cell membrane synthesis pathway. Chifukwa terbinafine imalepheretsa kutembenuka kwa squalene kukhala lanosterol, ergosterol singapangidwe. Izi zimaganiziridwa kuti zisintha ma cell membrane permeability, kupangitsa fungal cell lysis.
1. Terbinafine Hcl imagwira ntchito makamaka pa gulu la dermatophyte la bowa.
2. Monga kirimu kapena ufa wokwana 1%, amagwiritsidwa ntchito pamutu pa matenda akhungu monga jock itch (tinea cruris),
phazi la othamanga (tinea pedis), ndi mitundu ina ya zipere (tinea corporis). Zonona za Terbinafine zimagwira ntchito pafupifupi theka la nthawi yofunikira
ndi antifungal ena.
3. Oral 250mg mapiritsi nthawi zambiri zotchulidwa kuchiza onychomycosis, mafangasi msomali matenda, makamaka ndi dermatophyte.
kapena mitundu ya Candida. Matenda a misomali ya fungal amapezeka pansi pa msomali mu cuticle momwe mankhwala amagwiritsira ntchito pamutu
osatha kulowa mu ndalama zokwanira. Mapiritsi amatha, kawirikawiri, amayambitsa hepatotoxicity, kotero odwala amachenjezedwa za izi ndi
akhoza kuyang'aniridwa ndi kuyesa ntchito ya chiwindi. Njira zina zogwiritsira ntchito pakamwa zaphunziridwa.
4. Terbinafine angapangitse kapena kukulitsa lupus erythematosus. Anthu omwe ali ndi lupus erythematosus ayenera
kambiranani kaye za zoopsa zomwe zingachitike ndi dokotala musanayambe kulandira chithandizo.
Zogwirizana nazo
Newgreen fakitale imaperekanso ma amino acid motere:
Phukusi & Kutumiza
