• KodiTUDCA(Taurodeoxycholic Acid)
Kapangidwe:TUDCA ndi chidule cha taurodeoxycholic acid.
Gwero:TUDCA ndi mankhwala achilengedwe omwe amachotsedwa mu ndulu ya ng'ombe.
Kachitidwe Kachitidwe:TUDCA ndi bile acid yomwe imachulukitsa kuchuluka kwa bile acid m'matumbo, motero imathandiza kuti bile acid alowe m'matumbo. Kuphatikiza apo, TUDCA imathanso kuchepetsa kuyamwanso kwa bile acid m'matumbo, potero kumawonjezera kufalikira kwake mthupi.
Ntchito: TUDCAamagwiritsidwa ntchito makamaka pochiza matenda oyamba a biliary cholangitis (PBC) ndi matenda osamwa mowa a chiwindi + (NAFLD).
• Kodi UDCA (Ursodeoxycholic Acid) ndi chiyani?
Kapangidwe:UDCA ndi chidule cha ursodeoxycholic acid.
Gwero:UDCA ndi mankhwala achilengedwe omwe amachotsedwa ku bile.
Njira yochitira:UDCA ndi yofanana m'mapangidwe ake a bile acid mthupi, kotero imatha kusintha kapena kuwonjezera bile acid yomwe thupi lilibe. UDCA ili ndi zotsatira zambiri m'matumbo, kuphatikizapo kuteteza chiwindi, anti-inflammatory, ndi anti-oxidation.
Ntchito:UDCA imagwiritsidwa ntchito kwambiri pochiza matenda a biliary cholangitis (PBC), miyala ya cholesterol +, cirrhosis, matenda a chiwindi amafuta osamwa mowa (NAFLD) ndi matenda ena.
• Kodi pali kusiyana kotani pakati pa?TUDCAndi UDCA pakuchita bwino?
Ngakhale kuti TUDCA ndi UDCA zonse zili ndi zotsatira zoteteza chiwindi, njira zawo zingakhale zosiyana. TUDCA imagwira ntchito makamaka powonjezera kuchuluka kwa bile acid m'matumbo, pomwe UDCA imafanana ndi kapangidwe kake ka bile acid ndipo imatha kusintha kapena kuwonjezera bile acid yomwe thupi lilibe.
Zonsezi zingagwiritsidwe ntchito pochiza matenda osiyanasiyana a chiwindi, koma akhoza kusonyeza zotsatira zosiyana kapena ubwino pochiza matenda ena. Mwachitsanzo, TUDCA ikhoza kukhala yothandiza kwambiri pochiza matenda a biliary cholangitis (PBC).
Mwachidule, onse a TUDCA ndi UDCA ndi mankhwala othandiza, koma pali kusiyana pakati pa magwero awo, njira zogwirira ntchito, ndi kuchuluka kwa ntchito. Ngati mukuganiza kugwiritsa ntchito mankhwalawa, ndi bwino kukaonana ndi dokotala kuti mudziwe zambiri za malangizo ndi malangizo.
NgakhaleTUDCAndi UDCA onse ndi bile acid, mapangidwe awo a maselo ndi osiyana pang'ono. Mwachindunji, TUDCA imapangidwa ndi molekyulu ya bile acid ndi molekyulu ya taurine yolumikizidwa ndi chomangira cha amide, pomwe UDCA ndi molekyulu yosavuta ya bile acid.
Chifukwa cha kusiyana kwa maselo, TUDCA ndi UDCA zimakhalanso ndi zotsatira zosiyana m'thupi la munthu. TUDCA ndiyothandiza kwambiri kuposa UDCA pakuwongolera kayendedwe ka aimpso, kuteteza chiwindi, ndi kulimbikitsa impso. Kuphatikiza apo, TUDCA imakhalanso ndi zotsatira za antioxidant ndipo imakhala ndi zotsatira zingapo zama pharmacological monga sedation, antianxiety, and antibacterial effect.
TUDCA(taurodeoxycholic acid) ndi UDCA (ursoxycholic acid) onse ndi mitundu ya bile acid, ndipo onse ndi zinthu zachilengedwe zotengedwa m'chiwindi.
UDCA ndiye chigawo chachikulu cha bile. Imawonjezera ntchito ya chiwindi powonjezera katulutsidwe ka bile acid, potero imachepetsa kuchuluka kwa bile acid. Ntchito yake yayikulu ndikuchiza matenda a cholestatic monga cirrhosis, cholelithiasis, etc. Kuphatikiza apo, zimathandizanso kuchepetsa mafuta m'thupi.
TUDCAndi kuphatikiza kwa taurine ndi bile acid. Ikhozanso kupititsa patsogolo ntchito ya chiwindi, koma machitidwe ake ndi osiyana ndi a UDCA. Itha kupititsa patsogolo mphamvu ya antioxidant ya chiwindi ndikuteteza chiwindi kuti zisawonongeke ndi zowonongeka. Kuphatikiza apo, zimathandizira kukulitsa chidwi cha insulin, kuchepetsa shuga wamagazi, komanso kukhala ndi anti-chotupa.
Kawirikawiri, UDCA ndi TUDCA onse ndi oteteza chiwindi abwino, koma njira zawo zogwirira ntchito ndizosiyana ndipo ndizoyenera matenda osiyanasiyana ndi anthu. Ngati muyenera kugwiritsa ntchito mankhwalawa awiriwa, ndi bwino kuwagwiritsa ntchito motsogozedwa ndi dokotala kuti mupewe zovuta.
Nthawi yotumiza: Dec-09-2024
