Pachitukuko chodabwitsa, asayansi apeza kuthekera kwa matrine, gulu lachilengedwe lochokera ku muzu wa chomera cha Sophora flavescens, polimbana ndi khansa. Kupezeka kumeneku kukuwonetsa kupita patsogolo kwakukulu pankhani ya oncology ndipo kumatha kusintha chithandizo cha khansa.
Ndi chiyaniMatrine?
Matrine akhala akugwiritsidwa ntchito ngati mankhwala achi China chifukwa cha anti-inflammatory and anti-cancer. Komabe, njira zake zenizeni zogwirira ntchito sizinapezekebe mpaka pano. Ochita kafukufuku posachedwapa achita kafukufuku wambiri kuti athetse njira za maselo zomwe matrine amachitira zotsutsana ndi khansa.
Kupyolera mu kafukufuku wawo, asayansi apeza kuti matrine ali ndi mphamvu zotsutsana ndi proliferative ndi pro-apoptotic, kutanthauza kuti akhoza kulepheretsa kukula kwa maselo a khansa ndikupangitsa kuti maselo awo afa. Kuchita kwapawiri kumeneku kumapangitsa matrine kukhala munthu wodalirika pakupanga mankhwala atsopano a khansa.
Komanso, kafukufuku wasonyeza zimenezomatrineimatha kulepheretsa kusamuka komanso kuwukira kwa ma cell a khansa, omwe ndi njira yofunika kwambiri pakufalikira kwa khansa. Izi zikuwonetsa kuti matrine sangakhale othandiza pochiza zotupa zoyambirira komanso kupewa metastasis, vuto lalikulu pakuwongolera khansa.
Kuphatikiza pa zotsatira zake zachindunji pama cell a khansa, matrine apezeka kuti amasintha chotupa cha microenvironment, kupondereza mapangidwe a mitsempha yatsopano yamagazi yomwe ili yofunikira pakukula kwa chotupa. Katunduyu wotsutsa-angiogenic amathandiziranso kuthekera kwa matrine ngati mankhwala oletsa khansa.
Kupezeka kwa mphamvu yolimbana ndi khansa ya matrine kwadzetsa chisangalalo pakati pa asayansi, ndipo ochita kafukufuku tsopano akuyang'ana kwambiri kufufuza ntchito zake zochizira. Mayesero azachipatala ali mkati kuti awunike chitetezo ndi mphamvu ya chithandizo cha matrine kwa odwala khansa, kupereka chiyembekezo cha chitukuko cha mankhwala atsopano ndi opambana a khansa.
Pomaliza, vumbulutso laza matrineAnti-cancer properties ndi gawo lofunika kwambiri pankhondo yolimbana ndi khansa. Ndi njira zake zambiri zogwirira ntchito komanso zotsatira zabwino zachipatala, matrine ali ndi lonjezo lalikulu ngati chida chamtsogolo polimbana ndi matendawa. Pamene kafukufuku m'derali akupitilirabe, kuthekera kwa matrine pakusintha chithandizo cha khansa sikungatheke.
Nthawi yotumiza: Sep-02-2024
