• Kodi N'chiyani?Lycopene ?
Lycopene ndi carotenoid yachilengedwe, yomwe imapezeka mu zipatso ndi ndiwo zamasamba monga tomato. Kapangidwe kake ka mankhwala kumakhala ndi 11 conjugated ma bond awiri ndi 2 non-conjugated ma bond awiri, ndipo ali ndi antioxidant ntchito yolimba.
Lycopene imatha kuteteza umuna ku ROS, potero kumapangitsa kuti umuna ukhale wabwino, kuletsa prostate hyperplasia, khansa ya prostate cell carcinogenesis, kuchepetsa kuchuluka kwa chiwindi chamafuta, atherosulinosis ndi matenda amtima, kukonza chitetezo chamunthu, ndikuchepetsa kuwonongeka kwa khungu chifukwa cha kuwala kwa ultraviolet.
Thupi la munthu silingathe kupanga lycopene palokha, ndipo limatha kulowetsedwa kudzera mu chakudya. Pambuyo mayamwidwe, izo makamaka kusungidwa mu chiwindi. Itha kuwoneka mu plasma, ma seminal vesicles, prostate ndi minofu ina.
• Ubwino Wake Ndi Chiyani?LycopeneKwa Kukonzekera Kwa Mimba Yamamuna?
Pambuyo pa RAGE activation, imatha kuyambitsa ma cell ndikupangitsa kupanga ROS, potero kumakhudza ntchito ya umuna. Monga antioxidant wamphamvu, lycopene imatha kuzimitsa mpweya wa singlet, kuchotsa ROS, ndikuletsa ma lipoprotein a umuna ndi DNA kukhala oxidized. Kafukufuku wawonetsa kuti lycopene imatha kuchepetsa kuchuluka kwa cholandilira cha advanced glycation end products (RAGE) mu umuna wamunthu, potero kumapangitsa kuyenda kwa umuna.
Mankhwala a Lycopene ali ndi machende ambiri a amuna athanzi, koma otsika mwa amuna osabereka. Kafukufuku wazachipatala apeza kuti lycopene imatha kupititsa patsogolo umuna wa amuna. Amuna osabereka azaka zapakati pa 23 mpaka 45 adafunsidwa kuti amwe lycopene pakamwa kawiri pa tsiku. Miyezi isanu ndi umodzi pambuyo pake, ndende ya umuna, ntchito ndi mawonekedwe awo adayang'aniridwanso. Amuna atatu mwa magawo atatu aliwonse anali atasintha kwambiri kuyenda kwa umuna ndi morphology, ndipo umuna umakhala wabwino kwambiri.
• Ubwino Wake Ndi Chiyani?LycopeneKwa Male Prostate?
1. Prostatic Hyperplasia
Prostatic hyperplasia ndi matenda ofala mwa amuna, ndipo m'zaka zaposachedwa, chiwerengero cha anthu chikuchepa kwambiri. Zizindikiro zotsika za mkodzo (kuthamanga kwa mkodzo / kukodza pafupipafupi / kusakwanira) ndizizindikiro zazikulu zachipatala, zomwe zimakhudza kwambiri moyo wa odwala.
Lycopeneimatha kuletsa kuchuluka kwa maselo a prostate epithelial, kulimbikitsa apoptosis mu minofu ya prostate, kulimbikitsa kulumikizana kwapakati kuti mupewe kugawanika kwa maselo, komanso kuchepetsa kuchuluka kwa zinthu zotupa monga interleukin IL-1, IL-6, IL-8 ndi chotupa necrosis. factor (TNF-α) kuti ikhale ndi zotsatira zotsutsa-kutupa.
Mayesero azachipatala apeza kuti lycopene imatha kusintha prostate hyperplasia komanso mawonekedwe osalala a minofu ya chikhodzodzo mwa anthu onenepa ndikuchepetsa zizindikiro za mkodzo wam'munsi mwa amuna. Lycopene ili ndi chithandizo chabwino komanso chowongolera pazizindikiro zam'munsi zamkodzo za amuna zomwe zimayambitsidwa ndi prostate hypertrophy ndi hyperplasia, zomwe zimagwirizana ndi antioxidant wamphamvu komanso anti-yotupa zotsatira za lycopene.
2. Khansa ya Prostate
Pali mabuku ambiri azachipatala ochirikiza zimenezolycopenemuzakudya za tsiku ndi tsiku zimathandizira kwambiri popewa khansa ya prostate, ndipo kumwa lycopene kumayenderana moyipa ndi chiopsezo cha khansa ya prostate. Njira yake imakhulupirira kuti ikugwirizana ndi kukhudza mawonekedwe a majini ndi mapuloteni okhudzana ndi chotupa, kuletsa kuchulukana kwa maselo a khansa ndi kumamatira, komanso kulimbikitsa kulumikizana kwapakati.
Kuyesa zotsatira za lycopene pa kuchuluka kwa kupulumuka kwa maselo a khansa ya prostate: M'mayesero azachipatala, lycopene idagwiritsidwa ntchito pochiza ma cell a khansa ya prostate DU-145 ndi LNCaP.
Zotsatira zinasonyeza zimenezolycopeneanali ndi cholepheretsa kwambiri pakukula kwa ma cell a DU-145, ndipo zolepheretsa zidawoneka pa 8μmol/L. Zotsatira zoletsa za lycopene pa izo zinali zogwirizana ndi mlingo, ndipo chiwerengero chapamwamba choletsa chikhoza kufika 78%. Panthawi imodzimodziyo, ikhoza kulepheretsa kwambiri kufalikira kwa LNCaP, ndipo pali mgwirizano woonekeratu wa mlingo. Pazipita zopinga mlingo pa mlingo wa 40μmol/L akhoza kufika 90%.
Zotsatira zikuwonetsa kuti lycopene imatha kuletsa kuchuluka kwa maselo a prostate ndikuchepetsa chiopsezo cha khansa ya prostate kukhala khansa.
Nthawi yotumiza: Nov-20-2024
