Epimedium (Horny Goat But) Tizilomboka

URELLIALIal Carcinoma ndi amodzi mwa khansa yodziwika bwino kwambiri, yokhala ndi chotupa chotupa komanso metastasis kukhala zazikulu zazikuluzikulu. Mu 2023, pafupifupi 168,560 milandu ya khansa yamikodzo idzapezeka ku United States, pafupifupi pafupifupi 32,590 kufa; Pafupifupi 50% ya milandu iyi ndi uripolial carcinoma. Ngakhale kupezeka kwa njira zatsopano zothandizira chithandizo, monga pdteumpy-ndunanti ya pd1 antibinumy-pochokera mkati mwa immuluthepy, oposa theka la odwala a Urcinoma sakuyankha mankhwalawa. Chifukwa chake, pali kufunika kofufuza mankhwala atsopano a njira zatsopano za matenda a urtinoma a carcinoma odwala.

Icariin. Tinatenga, Ita imapangidwa ku ICRARINT (ICT), yomwe imabweretsa zotsatirapo zake. Ica ili ndi zochitika zingapo zachilengedwe, kuphatikizapo reformity kupewa matenda, kukhala ndi antioxidantant katundu, ndikulepheretsa kupanduka. Mu 2022, makapisozi a Icaritin ali ndi ICT monga chopangira chachikulu adavomerezedwa ndi mayina a China National Zakudya makonzedwe oyambira hepatocellum carcinoma. Kuphatikiza apo, zinawonetsa kukhala kothandiza pakupitiliza kupulumuka kwa odwala omwe ali ndi Hepatocellular carcinoma. ICT sichimangopha zotupa popanga apopetosis ndi autophagy, komanso imayang'aniranso chimbudzi chambiri komanso kulimbikitsa kuyankha kwa anti-taborm. Komabe, makina apadera omwe ilot amayang'anira tme, makamaka mu urtinoma carcinoma, sichimamveke bwino.

Posachedwa, ofufuza ku Dipatimenti ya Urology, yunivesite ya Hudan inafalitsa nkhani ya urfil Exticler Church B. Phunziro lidawululira kutiicariinKuchepetsa chotupa ndikupita patsogolo poletsa kulowa kwa neutrophil ndi kapangidwe kake, kuwonetsa kuti little akhoza kukhala maukonde atsopano oletsa carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinoma carcinomar carcinoma.

Chotupa chotupa ndi metastasis ndizazikulu zoyambitsa imfa ku Urcinoma carcinoma. Mu chotupa chambiri, ma molectureory owongolera ndi ma cell angapo amthupi a cell cell cell celly termicity. Kutupa kwa microenmicence, kumalumikizidwa ndi misampha ya neutrophil ndi neutrophil misampha (maukonde), amalimbikitsa chotupa cha metastasis. Komabe, palibe mankhwala osokoneza bongo omwe amalepheretsa neutrophils ndi maukonde.

Mu kafukufukuyu, ofufuzawo adawonetsa koyamba kutiicariin, Chithandizo choyambirira cha chakudya chapamwamba komanso chosachiritsika cha hepatocelar carcinoma, chimatha kuchepetsa maukonde oyambitsidwa ndi neicidal netisisis ndikuletsa kulowetsedwa kwa neutrophil mu chotupa mu chotupa chambiri. Kanema, itc imamangiriza ndikuletsa kulongosoka za Padi2 mu neutrophils, potero akulepheretsa Paii2-yemwe anali ndi mbiri yakale. Kuphatikiza apo, it Ict imalepheretsa mibadwo ya Ros, imalepheretsa njira yolowera ma mapu a Mapk, ndikuletsa zotupa za metastasis.

Nthawi yomweyo, Lict Pearobing Panali Patal Pail Pailand, potero potengera zomwe zidalembedwazo za neuthophil recruirments zobiriwira monga GMF ndi Il-6. Kutembenuka, kutsika kwa IS-6 kumapangitsa kuti malo oyendetsedwa ndi jak2 / Stat3 / Il-6 Axis. Mwa kuphunzira zitsanzo zamankhwala, ofufuzawo adapeza kulumikizana pakati pa neutrophils, maukonde, Uca Kuphatikizidwa ndi innictiogoioctoor kumatha kukhala ndi vuto la syrnergist.

Mwachidule, kafukufukuyu adapezaicariinKuchepetsa chotupa ndikupita patsogolo ndikulepheretsa kugonjetsedwa kwa neutrophil ndi spyesis ndi ma neutrophils ndi ma neutrophils ndi maukonde olakwika mu matenda a Trucninor Carcinoma. Kuphatikiza apo, ICC yophatikizidwa ndi anti-pd1 Immunothepy imakhala ndi njira yothandizira, ndikuwonetsa njira yomwe ingachitire odwala omwe ali ndi Uripor Carcinoma