Newgreen Supply Pharmaceutical 99% Purity Metallothionein Powder Material Metallothionein Mt Rabbit Chiwindi Zinc Metallothionein
Mafotokozedwe Akatundu
Metallothionein ndi puloteni yotsika kwambiri yamamolekyu yokhala ndi kuthekera komangiriza zitsulo komanso mawonekedwe apamwamba kwambiri. [1] Ma peptides amfupi olemera mu cysteine ogwirizana kwambiri ndi zitsulo zolemera zosiyanasiyana. Ndi puloteni yomwe ili ndi kulemera kochepa kwa maselo ndipo imakhala ndi zotsalira za cysteine ndi zitsulo. Zitsulo zophatikizidwa makamaka ndi cadmium, mkuwa ndi zinki, zomwe zimapezeka kwambiri muzamoyo zosiyanasiyana kuchokera ku tizilombo toyambitsa matenda kupita kwa anthu, ndipo kapangidwe kake kamakhala kotetezedwa kwambiri.
COA
ZINTHU | ZOYENERA | ZOTSATIRA ZAKE |
Kuyesa | 98% mphindi Metallothionein | Zimagwirizana |
Mtundu | Ufa Woyera | Zimagwirizana |
Kununkhira | Palibe fungo lapadera | Zimagwirizana |
Tinthu kukula | 100% yadutsa 80mesh | Zimagwirizana |
Kutaya pakuyanika | ≤5.0% | 2.35% |
Zotsalira | ≤1.0% | Zimagwirizana |
Chitsulo cholemera | ≤10.0ppm | 7 ppm |
As | ≤2.0ppm | Zimagwirizana |
Pb | ≤2.0ppm | Zimagwirizana |
Zotsalira za mankhwala | Zoipa | Zoipa |
Chiwerengero chonse cha mbale | ≤100cfu/g | Zimagwirizana |
Yisiti & Mold | ≤100cfu/g | Zimagwirizana |
E.Coli | Zoipa | Zoipa |
Salmonella | Zoipa | Zoipa |
Mapeto | Gwirizanani ndi Specification | |
Kusungirako | Kusungidwa Pamalo Ozizira & Owuma, Khalani Kutali Ndi Kuwala Kwamphamvu Ndi Kutentha | |
Alumali moyo | 2 years atasungidwa bwino |
Ntchito
MT ndi puloteni yomanga zitsulo yokhala ndi cysteine. Gulu lake la sulfhydryl limatha kukhetsa mwamphamvu zitsulo zapoizoni ndikuzitulutsa m'thupi, potero zimakwaniritsa kuchotseratu poizoni. [4] MT imagwirizana ndi kagayidwe ka zitsulo. M'magulu onse a mammalian, MT-1 ndi MT-2 amawonetsedwa mogwirizana. MT-3 ndi membala wapadera wa ubongo m'banja lino. Ikhoza kumanga zinki ndi mkuwa ndipo imakhala ndi ntchito zofunika kwambiri za neurophysiological ndi neuromodulation. Kafukufuku wokhudza zamoyo zambiri zam'madzi awonetsa kuti MT imagwira ntchito yofunika kwambiri pakuwongolera zinthu zoyambira zitsulo, ndipo imakhala ndi zoletsa komanso zowononga zinthu zomwe sizili zachitsulo. MT imatha kuchepetsa kawopsedwe ka zitsulo zolemera kwambiri m'thupi pophatikiza ndi zitsulo zolemera, ndipo pakadali pano ndiye njira yabwino kwambiri yothanirana ndi tizilombo toyambitsa matenda.
Chitetezo cha chilengedwe
Pogwiritsa ntchito zizindikiro za kuphatikiza kwa MT ndi zitsulo, ndizotheka kuswana kapena kugwiritsa ntchito majini kuti akhazikitse dongosolo lapamwamba la MT kuti athetse kuwonongeka kwazitsulo zolemera. Malinga ndi malipoti, fodya wopatsirana ndi yisiti MT gene amatha kukulitsa kwambiri kuyamwa kwa cu2 mu dothi loipitsidwa, ndipo njirayi ingagwiritsidwe ntchito pochiza madera omwe ali ndi zitsulo zolemera.
MT ndi kukana kwa radiation
Ma radiation a ionizing amatha kupanga ma free radicals ambiri, omwe amatha kuwononga zamoyo mwachindunji kapena mwanjira ina. Kafukufuku wasonyeza kuti kuwongolera pakamwa kwa MT kumatha kutalikitsa nthawi yopulumuka ya mbewa zomwe zimawonetsedwa ndi radiation yanthawi imodzi ya ionizing, ndikuchepetsa kuwonongeka kwa chitetezo chamthupi chomwe chimayambitsidwa ndi ma radiation a nthawi imodzi komanso angapo otsika kwambiri. . Oral MT imatha kuyamwa ma Cys ambiri omwe amalowa m'thupi. Amapereka zipangizo zokonzera zomangira za disulfide zosweka ndi ma radiation m'thupi.
MT ndi Parkison (PD) matenda
Zoyesera zambiri zatsimikizira kuti MT ili ndi mphamvu yoteteza dongosolo lamanjenje. Kuyesera kwawonetsa kuti mu mbewa za transgenic, MT-1 overexpression imatha kusintha zizindikiro za encephalitis ndikulimbikitsa kukonza ubongo. Ndi chinthu choteteza m'maselo a mitsempha. Kupyolera mu phunziro la chitsanzo chobaya makoswe ndi chitsanzo cha ischemia, apeza kuti MT-3 ikukhudzidwa ndi kukonzanso kuwonongeka kwa dongosolo la mitsempha. Matenda a PD amayamba chifukwa cha kulowetsedwa kwa ma radicals aulere ndi 6-hydroxydopamine, ndi zina zoyambitsa MT isoforms mu ubongo, monga kupsinjika kwa okosijeni, ma cytokines ndi njira zotupa, zimatha kuteteza neurotoxicity iyi, yomwe ilibe ku MT clearance Base yokhudzana.
Mapulogalamu
Metallothionein (MT) ndi mtundu wa mapuloteni ochepa omwe amakhala ndi cysteine ndi zitsulo. Chifukwa cha kuthekera kwake kumangiriza ma ion ambiri achitsulo ndi ntchito yake yapadera ya thupi, idaperekedwa chidwi kwambiri pazachilengedwe. Mbiri ya kafukufuku wa MT yakhala zaka zoposa 40, ndipo kafukufuku wokhudza mapangidwe ake, makhalidwe ake, kayendetsedwe ka majini ndi ntchito zamoyo wakhala akuzama mozama. Chiyembekezo chogwiritsa ntchito MT ndichambiri, kuphatikiza koma osalekezera ku:
1. Medical field : MT imagwiritsidwa ntchito makamaka m'matenda amtima ndi cerebrovascular ndi zotupa, koma sizinagwiritsidwe ntchito pa khunyu.
2. Thanzi lazakudya komanso zowonjezera zodzikongoletsera : MT itha kugwiritsidwa ntchito ngati chowonjezera muzakudya, zowonjezera zaumoyo ndi zodzoladzola kuti mupereke zina zowonjezera zaumoyo.
3. Genetic engineering reagent : Mu genetic engineering, MT imagwiritsidwa ntchito ngati chothandizira kulimbikitsa kafukufuku ndi kugwiritsa ntchito majini.
4. Chemical and Environmental Protection : MT imagwiritsidwanso ntchito m'malo oteteza mankhwala ndi chilengedwe, mwachitsanzo kuchotsa zitsulo zovulaza.
Zolemba za labotale yazaulimi : MT itha kugwiritsidwa ntchito ngati nkhani yoyesera pazoyeserera zaulimi, makamaka pophunzira za kuipitsidwa kwa zitsulo zolemera komanso kulolerana ndi zitsulo zolemera.
5. Kuonjezera apo, MT imakhalanso ndi ntchito yogwira nawo ntchito yosungiramo zinthu zosungirako, zoyendetsa ndi kagayidwe kake ka trace elements zinc ndi mkuwa, detoxification ya heavy metal elements cadmium, mercury ndi lead, kutsutsa ma radiation a ionizing ndi kuchotsa magulu aulere a hydroxyl. Majini achilengedwe a MT adapangidwa kukhala fodya, petunia ndi zomera zina ndi genetic engineering, ndipo zomera za transgenic zimasonyeza kukana kwambiri kuipitsidwa kwa cadmium. Ngati jini ya MT imasamutsidwa ku clover ndi duckweed ndikubzalidwa m'nthaka kapena madzi oipitsidwa ndi cadmium ndi mercury, imatha kuyamwa zitsulo zambiri zapoizoni m'nthaka ndi m'madzi, ndikuthandizira kuchotsa zitsulo zovulaza.
Zogwirizana nazo:
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